In the three decades since landmark legislation framed the marketplace, dietary supplements have proliferated, offering consumers an expanding menu of products.
The voluntary set of industry guidelines calls for the immediate disposal of “irreparably defective” botanical raw materials, ingredients, or products.
The court entered judgment against JT Best Deals LLC for trademark infringement and tortious interference of existing contracts and business relationships.
Gateway Health Sciences’ Dichrostachys glomerata extract was associated with greater weight loss, reduced food cravings, and improved mood compared to placebo.
PhytoGaia has been honored with the prestigious NutraIngredients-Asia 'Start-Up' Award, becoming the first-ever Malaysian company to win this accolade!
Brands have runway to build on traditional, familiar ingredients like protein and probiotics to support modern health issues like digestion, mood, sleep, etc.
By Julian Mellentin, New Nutrition Business10.07.24
Without more resources, FDA can’t conduct enough inspections to get an accurate picture of the marketplace, highlighting the importance of self-regulation.
The acquisition includes dsm-firmenich’s fish oil business for foods, beverages, supplements, and pharmaceuticals, and the MEG-3 brand and its facilities.
The global retailer launched a new house brand, and partnered with several pet care brands to offer products designed to support the health of dogs and cats.
Private label brand PharmaLinea’s vitamin and nucleotide complex appeared to offer greater benefit than placebo in a population undergoing physical therapy.
The yeast-derived, human-equivalent lactoferrin ingredient is formulated to digest similarly to human lactoferrin, compared to a bovine-sourced counterpart.
The cannabinoid was found to improve sleep quality with no side effects in 1,000 people, at levels more significant than standard-dose melatonin supplements.
The new probiotic products, Pathways Support and Mood Support, were studied in people with autism spectrum disorder by Arizona State University researchers.
This versatile ingredient has been clinically studied for safety, quality, and stability, offering manufacturers an efficacious product with reliable supply.
At the 12th annual Legal, Regulatory, and Compliance Forum on Dietary Supplements, FDA and FTC officials, and lawyers discussed a grab bag of hot topics.
The former Walmart lead e-commerce counsel specialized in helping clients create user experiences that meet advertising, marketing, and privacy requirements.
The blend of rosemary, olive leaves, lemon verbena, and Japanese pagoda tree was linked to improved physiological measures of scalp health after 12 weeks.
During smoking cessation, supplementing with IFF’s Neuravena was associated with better self-reported mood, sleep, and overall well-being over eight weeks.
The brief continued to argue that a preliminary injunction should prevent New York’s supplement age restriction from going into effect until the lawsuit ends.
The company’s herbal ingredients, such as BacoMind Bacopa monnieri, are being cultivated under a new model which combines ancient and modern methodologies.
Collagen, pet nutrition, sports nutrition, beauty-from-within, and biotics products will see the biggest shake-ups in the coming year, the company projects.
The live strains and their postbiotic forms are clinically evidenced to support an oral microbiome balance, measures of dental health, and fresh breath.
The initiative will focus on PLT’s lineup of disruptive, experiential product development concepts, which meet stringent quality and efficacy standards.
Learn about HMB’s benefits for muscle strength, market insights, and supplement formulation. This leucine metabolite is key for muscle health and performance.
The new test kit, available to healthcare practitioners, utilizes dried blood spot assay technology, which Chromadex reports is most suitable for accuracy.
While the studies await publication, new findings examined aged garlic extract in cystic fibrosis, aerobic fitness, cognition, circulation, and oral health.
The U.S. Chamber of Commerce, Consumer Healthcare Products Association, Food Marketplace Inc., and the National Association of Chain Drug Stores voiced support.
Proprietary supplement brands The Vitamin Shoppe, Vthrive The Vitamin Shoppe, BodyTech, and BodyTech Elite, are now available in over 180 countries via iHerb.
The appeal challenges interpretations which led to the recent U.S. District Court decision to let the law go into effect ahead of the lawsuit’s conclusion.
Quality of life for consumers is not just about living longer; it’s about shifting focus to how later years can be enjoyed just as much as our younger ones.
The new products are designed to support common side effects like digestive issues, loss of muscle mass and skin elasticity, and changes in blood sugar levels.
The range of symptoms and health needs experienced by women at this life stage represents one of the most important white spaces in today’s marketplace.
Diverse cultivation techniques, standardized testing methods, and unified labeling standards will help strengthen product integrity in a maturing market.
By Julie Daoust, PhD, Chief Scientific Officer, M2 Ingredients / Om Mushroom Superfood06.03.24
The nonprofit group works with over 1,200 local organizations and governments to reach more than 72 million women and children in 65 countries each year.
Treatment with NuLiv Science’s Verbasnol was associated with significant improvements in Global Acne Grading System scores in a small group of young women.
Those who consumed more than 7 g/d of olive oil had 28% lower risk of dying from dementia compared with participants who never or rarely consumed olive oil.
Our most-viewed stories in April included coverage of Amazon's new policy for dietary supplement sellers, Goli's acquisition, the beauty market, and more.
Can the agency better ensure product quality and safety without adding costs, stifling innovation, and constraining access to potentially beneficial products?
The recognition of women’s unique health needs and the concerted efforts to address them mark a significant shift in both culture and scientific endeavors.
By Melanie Bush, VP of Science & Research, Artemis International05.09.24
Probiotics customized to the individual’s gut microbiome and diet appeared to have efficacy in moderately improving cognitive and gastrointestinal problems.
The certificate audits the supply chain from seed to oil, for environmental protection, waste and energy management, social responsibility, and compliance.
A new House bill would amend the Food, Drug, and Cosmetic Act to grant FDA more authority against products that don't meet the definition of dietary supplement.
Givaudan’s ThinkBlue was found to support cognitive function greater than placebo in two separate studies involving a total of 72 healthy older adults.
In addition to stricter testing requirements, all certificates of authenticity must come directly from third-party companies partnered with the retailer.
The latest of what will be several guidance documents on the NDI process provides updates on the agency’s proposed method to handle proprietary information.
Karallief’s KaraShield botanical blend was associated with reduced frequency and severity of URT symptoms, greater serum IgG, and lower markers of inflammation.
For elite athletes, active lifestylers, and those in the golden years, the supplement market offers compelling options to support strength and mobility.
Move Nutrition Network survey of dietitians, nutritionists, and trainers reveals opportunity for suppliers and brands to reach a growing consumer base.
Liposomal encapsulation is a nascent technology in the supplements space, and proving liposomes were created requires a battery of technical, expensive tests.
It’s common for third-party labs to leave out inorganic bromide and dithiocarbamates in supplement testing, despite being required by USP <561> standards.
Taking the complex of Sphaeranthus indicus and Mangifera indica extracts led to significant improvements in functional measures of strength in a clinical study.
Foods, drinks, and supplements fortified with phytonutrients can help address the side effects of hustle culture, screen addiction, and sedentary living.
By Melanie Bush, VP of Science & Research, Artemis International02.12.24
High fish and vegetable intake and low amounts of sugary beverages, starting at one year old, had a significant impact on IBD risk in over 80,000 people.
Our most-viewed stories in January included Amazon's warning letter from FDA, economically-motivated adulteration in botanicals, and supplement trends to watch.
The agency issued a warning about “Neptune’s Fix” supplements, and all others containing the substance, which can serious, potentially lethal side effects.
An analysis co-authored by STRIPED's director estimated the prevalence of “diet pill,” laxative, and diuretic use across adolescent populations in 90 studies.
The agency found that several “tejocote” supplements were adulterated with the toxic botanical, following a similar investigation in September of last year.
Based on how chlorella and spirulina support muscle remodeling in young, healthy adults, these algae serve as a sustainable alternative to animal protein.
Qualia Senolytic, a nine-ingredient formula designed to support the body in eliminating senescent cells, improved self-reported joint function within six months
Despite initial negative findings, a secondary analysis of the large-scale study found cocoa extract improved cognition for those with poor diet at baseline.
While the study didn't include calcium supplementation, it was nonetheless "striking" that vitamin D alone made no difference, according to the authors.
The European Commission approved of 3-fucosyllactose as a novel food ingredient, marking a milestone for improving market access of a broader range of HMOs.
The Spilanthes acmella extract was associated with significant increases in mean testosterone levels, muscle mass, and self-reported sexual satisfaction.
The first-of-its-kind state bill, which bans the sale of “weight loss” and “muscle building” supplements to minors, is slated to go into effect in April 2024.
The coalition of CBD stakeholders plans to advocate for CBD to be regulated as a dietary ingredient with a set of unique testing and labeling standards.
Consumers are focused on wellness throughout their lives, aiming to proactively address concerns related to joint health/mobility, blood sugar, and more.
Careful consideration must be paid to ingredient form, how it was processed, level of bioactives, and whether it has been scientifically substantiated.
By Melanie Bush, VP of Science and Research, Artemis International, Inc.11.20.23
There’s plenty of research in the field of nutritional neuroscience to support structure-function claims, according to researcher Douglas Kalman, PhD, RD.
Due to “competing priorities,” the agency provided no clarification on how it interprets the provision of DSHEA which defines drugs versus dietary ingredients.
The study conducted by MDbio in partnership with Radicle Science found improvements in measure of sleep, stress, and anxiety in a population of 620 adults.
Sleeproot, a standardized extract by OmniActive Health Technologies, improved sleep latency, duration and efficiency, as well as self-reported anxiety.
Young people in particular are hungry for health benefits from food. As nutrition ‘rules’ change and need-states evolve, new business opportunities emerge.
By Julian Mellentin, New Nutrition Business11.01.23
The ingredient, standardized to thymoquinone and low free fatty acid content, is classified as a novel food to be sold in dietary supplements in the country.
The collaboration aims to bring products to market that combine and enhance the effectiveness of botanical extracts and ingredients from both companies.
During fermentation, microorganisms engage with the berry substrate, resulting in diverse chemical transformation that yields heightened polyphenol content.
The turmeric extract, standardized to 95% curcuminoids, is fully water dispersible, and three times more potent than competing extracts, the company reports.
FDA’s expanded enforcement authority, combined with new statutory and regulatory requirements, will lead to added scrutiny of cosmetics ingredients and claims.
By Todd Harrison and Melanie English, Venable LLP10.16.23
With Expert’Biome, the company will offer further product development services, including strain R&D, bioprocess scaling, drug manufacturing, and other steps.
In addition to a long list of ingredients to learn about, representatives will be on hand to discuss the history of commitment toward environmental stewardship.
The company’s Biotis Fermentis, which combines protein, prebiotics, and probiotics, can help address digestive health challenges connected to heavy training.
USP’s dietary ingredient verification program consists of extensive GMP facility audits, quality control and manufacturing evaluations, and lab testing.
Convenient product formats like gummies and beverages offer broad appeal, while multifunctional dietary supplement formulas offer value for varied need states.
Vitaquest International's new facility comes with fluidized bed process technologies enabling particle and powder engineering for foods and dietary supplements.
The new multi-ingredient product by Touchstone Essentials contains a plant-based enzyme evidenced to convert glucose molecules from food into resistant starch.
The guidance, issued this year is a departure from common marketing practice of dietary supplements and food, and misrepresents the state of the law, CRN said.
The trade organization said the notices issued earlier this year were inconsistent with regulatory practice, and unenforceable because they violate due process.
The formulation contains Lactobacillus plantarum LPLDL, K2Vital Delta from Kappa Bioscience, and thiamine, a form of vitamin B1 with an EFSA heart health claim.
Allaume, who has spent a 24-year tenure in the nutraceuticals industry, will be responsible for brand visibility and stimulating further growth in the region.
Those who supplemented with Probiotical’s Bifizen had improved moods sustained through a washout period, as well as increases in circulating serotonin.
The prebiotic fiber received approval for eight claims in total, and unrestricted use in dietary supplements regulated by the Therapeutic Goods Administration.
Supplementation with a strain called L. plantarum HEAL9 by Probi resulted in improved test performance in 129 healthy individuals with self-reported stress.
Our most-viewed stories in July included a proposed bill to cover supplement costs under HSAs/FSA, FDA inaction on NMN, the herbal supplements market and more.
NXT USA’s TamaFlex improved joint comfort, function, aerobic capacity, and lower body strength of participants significantly, with biomarkers suggesting change.
Following an update from the agency, the trade association characterized the agency’s plan as ‘pulling back’ on its responsibility to regulate supplements.
The ingredients on display can help improve the textures and shelf lives of meat, poultry, seafood, tortillas, bakery products, snack foods, sauces, and more.
Evidence mounts for the health benefits of PACs, and future innovations in quality and testing will improve efficacy while revealing other health benefits.
The gaming industry has swelled to exorbitant numbers generating more revenue than digital music, film, video streaming, the NFL and the Olympics combined.
As a global player in oleochemicals and phytonutrients, KLK OLEO/ Davos Life Science offers an array of high quality, natural and sustainable products.
The Founder & Executive Director of the American Botanical Council reflects on nearly 50 years of industry experience and the advancement of ABC's mission.
Learn about the need for more eye health solutions, the science supporting EYEMUSE™, opportunities for its application in dietary supplements, and more.
While variety in food patterns implies diverse nutrient needs, few of hundreds of prenatal supplements assessed were suitable for 90% of pregnant participants.
MoCRA expands FDA’s authority over cosmetics with requirements for safety substantiation, adverse event reporting, facility registration, and product listing.
By Evelina J. Norwinski, Elizabeth Trentacost, and Ryan D. White, Arnold & Porter04.13.23
A bill which offered a slate of protections for people with eating disorders was amended in order to remove dietary supplement restrictions from the equation.
Those with higher blood erythritol levels were shown to have elevated risk of experiencing a major adverse cardiac event such as heart attack, stroke or death.
In over 110,000 subjects, those in the highest quintile for DHA status were 26% less likely to be hospitalized compared to those with the lowest DHA status.
In a group of 100 patients, a quercetin ingredient marketed by Indena was linked to milder symptoms and faster conversion from positive to negative tests.
The site will focus on pharmaceutical and nutraceutical trials on cardiovascular disease, hypertension, dyslipidemia, diabetes, IBS, and weight management.
Compared to a standard caffeine supplement, Nutriventia’s CaffXtend resulted in a longer peak time, and significant improvements in self-reported effects.
Guidance includes recommendations on how to analyze hazards, evaluate a supplier’s performance and risk, and conduct appropriate verification activities.
Biotech company Marinova Pty Ltd is undertaking a $4.6 million expansion of its extraction facility in Australia, tripling its fucoidan production capacity.
Customization of formulas for men and women, based on evidence supporting unique health benefits, will take center stage and advance a growing marketplace.
RFI’s proprietary FermaPro solution can ferment any dry material—grains, grasses, seeds, botanicals, vegetables, and fruits—using bacterial or yeast cultures.
One 300 mg sustained-release capsule of Prolanza for 90 days improved memory recall, psychological wellbeing and sleep quality while reducing stress levels.
Soluble prebiotic carrot fiber known as RG-I (Rhamnogalacturonan-I) has a dual mode of action to help minimize the impact of everyday health challenges.
President and CEO of the Council of Responsible Nutrition discussed the industry’s need to strengthen communications, self-regulation, and transparency.
The study on CBD, and combinations containing CBD and other rare cannabinoids was history’s largest IRB-approved clinical trial on cannabis extracts to date.
Prinova is a one-stop-shop for 2,000+ ingredients, premixes, and flavors; and it has boots on the ground to maneuver around today’s supply chain pitfalls.
GABA, Apocynum venetum, and glycine have different mechanisms of action, which is important when creating a formula that addresses multiple sleep issues.
By Gene Bruno, MS, MHS, RH(AHG), VP, Scientific and Regulatory Affairs, NutraScience Labs09.20.22
Morus alba has a long history of safe use in TCM, and the evidence implicating this herb with the death of a Congressman’s wife is inconclusive at best.
Low Dog is an expert in dietary supplements, integrative medicine, and women’s health, and has been in the field of natural medicine for over 30 years.
Proposed legislation aims to create a new agency that would assume responsibilities for the regulation of food and dietary supplements currently held by FDA.
By Michael McGuffin, President, American Herbal Products Association (AHPA)09.13.22
Company operates according to current Good Manufacturing Practices under 21 CFR part 111 and part 117, with an FDA-compliant fulfillment facility in Reno, NV.
According to product recall reports, just a portion of products containing illegal ingredients were recalled following the issuance of warning letters.
With consumers prioritizing clean label appeal, producers are met with new opportunities to provide products that promote closer-to-nature ingredients.
New facility will be most sustainable PepsiCo Beverages North America plant in U.S. and create 250 new jobs for Denver-area residents, the company said.
Over 1,600 people with pain were randomized to take one of six cannabinoid formulations containing CBD and some combination of rare cannabinoids from OBX.
A review of 71 studies found a dose-dependent relationship between omega-3s and blood pressure reductions, most significant for those with hypertension.
The purchase of the organic, cold-pressed juice brand will help Bolthouse Farms expand its beverage portfolio to complement its lineup of juices and smoothies.
If a claim describes the substantiated role a nutrient or dietary ingredient plays in the body, plaintiffs cannot survive a motion for summary judgment.
By Todd Harrison, Partner; Richard Starr, Associate; and Olisa Onyiuke, Associate, Venable06.02.22
With fewer recalls than conventional foods, drugs, animal products and medical devices, supplements could be considered the safest class of goods FDA regulates.
By Michael McGuffin, President, American Herbal Products Association (AHPA)06.02.22
Amnesty for late NDI notifications is intended to encourage manufacturers and distributors to correct past failures while collecting safety data, FDA said.
The American College of Lifestyle Medicine, with multi-organizational support, said that plant-predominant diets can achieve remission ahead of other treatment.
The new Master’s degree program will equip working professionals with regulatory compliance and nutrition guidelines relevant to the supplements industry.
Gummies, beverages, stick packs, and snack-like products are on-trend, but brands have a lot to consider in terms of formulation and regulatory compliance.
Industry should view both proposed legislation and arguments against it with a critical eye, but let’s address legitimate concerns while dismissing strawmen.
By Steve Mister, President & CEO, Council for Responsible Nutrition04.26.22
Sen. Dick Durbin (D-IL) and Sen. Mike Braun (R-IN) introduced a bill that would require dietary supplement manufacturers to file product information with FDA.
Utah’s longest-serving Senator was known for working across the aisle, authoring or coauthoring some of the most consequential laws of the past half century.
Plaintiffs are monitoring whether a company abides by all relevant FDA regulations, so it’s important to understand requirements and confirm disclaimers.
By Todd Harrison, Partner; Kristen Klesh, Counsel; Olisa Onyiuke, Associate; and Melanie English, Associate Venable04.14.22
Technology that can track a sequence of transactions helps build trust among stakeholders along the supply chain, as well as between consumers and brands.
By Robert Galaza, CEO, TruTrace Technologies04.14.22
The U.S. Food and Drug Administration is prioritizing multiple ways to regulate the dietary supplements industry in its request for an $8.4 billion budget.
Adding CBD, a naturally anti-inflammatory ingredient, to the base 0.2% retinol solution, maintains the anti-aging properties, but with reduced side effects.
By Julius Few, MD; Michael Lee, MD; Alec Semersky; Emily Mariscal, LE; and Ginny Vachon, PhD04.07.22
The independent safety review of seven probiotic strains demonstrates to consumers that the probiotics were vetted through studies and expert panel consensus.
At Expo West, research experts from ChildLife Essentials discussed the role of nutraceuticals in the interplay between the gut, cognition, and immunity.
The patent-pending technology allows for sugar and sugar-free options, both compliant with USDA organic standards and international organic requirements.
With the tagline 'Illuminate the Science,' the database debuted at the GOED Exchange, featuring an abstract search section and an advanced search tool.
Most audits have been conducted on the harvests of other Boswellia species, leading to some confusion about the species used in dietary supplements and foods.
The FDA ruling on claims that cranberry can reduce UTI incidence will be used by the company as a launchpad for delivery system innovation, the supplier said.
Supplementing with NXT USA’s TamaFlex resulted in short-term improvement in self-reported pain scores and inflammatory markers at both high and low doses.
With B. subtilis DE111 for gut and immune support, bolstered by vitamins C or D, the kids' and adults' varieties are TruBiotics' first foray into gummies.
Based on NHANES data collected from cancer survivors, the authors of a review found that the use of supplements was linked to long-term, cost-effective benefit.
Following a review of the evidence, FDA now supports three types of claims on the research, which it still considers to be “inconsistent and inconclusive.”
A new animal study provides additional primary evidence for a whitepaper by Nature’s Crops, the makers of the omega-3-rich botanical ingredient Ahiflower.
In a study on 351 women, diets in early pregnancy characterized by fruits, vegetables, fiber, and lower fat content significantly reduced rates of GDM.
After issuing warning letters to companies claiming that NAC is excluded as a dietary ingredient, the agency's response to citizen petitions is still tentative.
A 16-day regimen of beneficial Lactobacillus strains improved nausea and vomiting, both commonplace issues pregnant women deal with in early pregnancy.
Hikaru Asari is a senior executive for Tokyo, Japan-based J-Oil Mills, Inc., brands and marketing, overseeing the company’s global fine materials products unit.
Pre-clinical studies conducted by researchers at the University of Tsukuba showed that astaxanthin and exercise improved signs of cognitive function in mice.
The two new isolates are designed to overcome taste challenges to meet consumers’ high expectations for taste, texture, and performance, the companies said.
What we’ve created is truly a unique product built specifically for the supplement industry and the challenges they face when formulating and labeling products.
The range of three products features hobamine, a novel ingredient tied to DNA protection and antioxidant activity, alongside several other emerging ingredients.
Compelling increases in online searches and social media discussions, especially among younger crowds, suggest people want more than just plant-based products.
SimPure offers similar viscosity, bulking functionality, and sensory profiles compared to maltodextrin, enabling 1-to-1 replacement in a range of applications.
Maizinol is derived from Zea mays corn leaf extract; UP360 is comprised of polysaccharide and polyphenol standardized extracts from aloe, poria, and rosemary.
Company specializes in analytical chemistry and microbiology testing for pharma, nutraceutical, dietary supplement, cosmetic, and cannabis/CBD industries.
The role pets play in U.S. households has been redefined, and more people are buying products designed to support a long and healthy life for their furry pals.
By Kevin Owen, PhD, Global Business Development, Companion Animals Lonza Consumer Health & Nutrition09.09.19
A total of 14 staff members are specifically trained in implementing the 21 CFR part 117 regulations, covering all of the company’s manufacturing facilities.
Peter Wojewnik is director of business development at Dicentra, a leading scientific and regulatory consulting firm based in Toronto with specialized expertise in the areas of natural health products, dietary supplements, OTCs, foods and cosmetics.