04.23.24
A prebiotic fiber sourced from upcycled carrot pomace marketed by NutriLeads as Benicaros was evidenced to promote the growth of beneficial, short-chain fatty acid-producing gut bacteria in a new study published in Biomedicine & Pharmacotherapy.
The research shows that daily servings of 300 mg of the fiber, known as rhamnogalacturonan-I (RG-I), increases the relative abundance of common beneficial bacteria, including Bifidobacterium, mainly B. adolescentis and B. longum., independent of variety in baseline gut microbiota composition.
“Benicaros consistently and predictably modulates the composition of the gut microbiota, despite the natural differences between individual gut microbiomes,” said Joana Carneiro, PhD, NutriLeads CEO. “The complex molecular structure of this prebiotic fiber selectively nourishes beneficial bacteria prevalent in most people. Remarkably, these beneficial effects were evident with daily servings of Benicaros as low as 300 mg.”
The present study is the third publication resulting from a randomized, placebo-controlled study of 146 healthy people. The participants were randomized to receive either a placebo, 300 mg, or 1500 mg of Benicaros daily for 8 weeks.
Previous findings supported the prebiotic fiber’s role in improving markers of immunity in subjects challenged with the common cold virus, by reducing the severity and duration of symptoms, which correlated with improved self-reported quality of life scores.
The new study specifically broke down changes observed in the gut microbiota of participants. Like the improvements to markers of immune function, changes in gut microbiota composition were also dose-dependent.
“The increase in abundance of other beneficial bacterial species known for their short chain fatty acid production indicates that Benicaros increases the metabolic capacity of the gut microbiota,” said study co-author Willem M. de Vos, PhD, professor of the human microbiome at the University of Helsinki and emeritus distinguished professor at Wageningen University. “This suggests that Benicaros contributes to a healthy gut environment thereby supporting overall health.”
The research shows that daily servings of 300 mg of the fiber, known as rhamnogalacturonan-I (RG-I), increases the relative abundance of common beneficial bacteria, including Bifidobacterium, mainly B. adolescentis and B. longum., independent of variety in baseline gut microbiota composition.
“Benicaros consistently and predictably modulates the composition of the gut microbiota, despite the natural differences between individual gut microbiomes,” said Joana Carneiro, PhD, NutriLeads CEO. “The complex molecular structure of this prebiotic fiber selectively nourishes beneficial bacteria prevalent in most people. Remarkably, these beneficial effects were evident with daily servings of Benicaros as low as 300 mg.”
The present study is the third publication resulting from a randomized, placebo-controlled study of 146 healthy people. The participants were randomized to receive either a placebo, 300 mg, or 1500 mg of Benicaros daily for 8 weeks.
Previous findings supported the prebiotic fiber’s role in improving markers of immunity in subjects challenged with the common cold virus, by reducing the severity and duration of symptoms, which correlated with improved self-reported quality of life scores.
The new study specifically broke down changes observed in the gut microbiota of participants. Like the improvements to markers of immune function, changes in gut microbiota composition were also dose-dependent.
“The increase in abundance of other beneficial bacterial species known for their short chain fatty acid production indicates that Benicaros increases the metabolic capacity of the gut microbiota,” said study co-author Willem M. de Vos, PhD, professor of the human microbiome at the University of Helsinki and emeritus distinguished professor at Wageningen University. “This suggests that Benicaros contributes to a healthy gut environment thereby supporting overall health.”
