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    Live From Shows

    Unigen Presenting New Botanical Ingredients for Immune Health and Sleep/Stress

    Maizinol is derived from Zea mays corn leaf extract; UP360 is comprised of polysaccharide and polyphenol standardized extracts from aloe, poria, and rosemary.

    Unigen Presenting New Botanical Ingredients for Immune Health and Sleep/Stress
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    10.19.21
    Unigen will introduce two new botanical ingredients for sleep/stress and immune health at this SupplySide West’s Presentation Theater and Booth 2957.
     
    Maizinol is a patented ingredient derived from Zea mays corn leaf extract and is a natural alternative to melatonin. UP360 is comprised of polysaccharide and polyphenol standardized extracts from Aloe, Poria, and Rosemary for maintaining immune homeostasis.
     
    Both presentations are scheduled in the early afternoon of Oct. 27 at the Supplier Presentation Theater and will be replayed online after the event on SSW 365 digital platform and www.unigen.net.
     
    Maizinol
    Unigen’s Director of Pre-Clinical Development Dr. Mesfin Yimam, DVM, MS, will present the detailed clinical results on Maizinol, including mechanism of action, preclinical efficacy, and safety profile.
     
    In the double-blind placebo-controlled clinical trial of healthy subjects on sleep quality and overall well-being, a statistically significant and dose-correlated increase of approximately 30% deep sleep time, improvement of sleep quality, and reduction of salivary cortisol were observed.
     
    According to Dr. Qi Jia, Unigen CEO and CSO, “These collective health benefits give Maizinol a competitive edge in the market, to meet the needs from consumers who have experienced stress and lack of restful sleep under the rampage of the pandemic.”
     
    Another human clinical trial of Maizinol is in development with a larger cohort. Jia added that Maizinol has a long history of safe human usage, once a-day dosing, lower cost per serving, and its high compatibility in formulating with other ingredients denotes its relative competitiveness to other similar ingredients on the market.
     
    UP360
    Jia will present pre-clinical and clinical data on Unigen’s immune health ingredient, UP360. The UP360 composition is comprised of polysaccharide and polyphenol standardized extracts from Aloe, Poria, and Rosemary that were formulated by evaluating the synergistic effects in protection of hyperoxia stressed macrophages.
     
    In an accelerated aging model, UP360 increased key innate and acquired immunity while protecting immune organs. Unigen also conducted a triple-blind placebo-controlled human clinical trial with influenza vaccine-immunized healthy subjects. UP360 resulted in a statistically significant increase of gamma delta T-cells, suggesting its benefits on enhanced immune surveillance in mucosal membranes.
     
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