• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    Reinforcing Omega-3 Supply Networks

    A Clearer Path to Weight Management: The Ozempic Factor

    Under Pressure: Stress and Mental Health Have Taken Center Stage

    Sustainable Business Development: Principles and Strategies for Progress

    Beauty IO MarketWatch: L’Oréal to Define the Next Era of Beauty Tech in CES 2024 Keynote
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Glossary
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    D2C Supplement Brand Launches Blood Sugar Support Supplement, Gluco-Control

    Natrol Launches First Non-Melatonin Sleep Supplement

    Metagenics Releases Consumer Survey on Menopausal Support Supplement

    Culturelle Probiotics Launches Women’s Health Awareness Campaign

    Women's Health Brand O Positiv Launches Essentials Line of Supplements
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    D2C Supplement Brand Launches Blood Sugar Support Supplement, Gluco-Control

    Natrol Launches First Non-Melatonin Sleep Supplement

    Metagenics Releases Consumer Survey on Menopausal Support Supplement

    Women's Health Brand O Positiv Launches Essentials Line of Supplements

    Growing Mushrooms At Home With Mistercap, Wiz Khalifa
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    D2C Supplement Brand Launches Blood Sugar Support Supplement, Gluco-Control

    Natrol Launches First Non-Melatonin Sleep Supplement

    Metagenics Releases Consumer Survey on Menopausal Support Supplement

    Culturelle Probiotics Launches Women’s Health Awareness Campaign

    Women's Health Brand O Positiv Launches Essentials Line of Supplements
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    D2C Supplement Brand Launches Blood Sugar Support Supplement, Gluco-Control

    Natrol Launches First Non-Melatonin Sleep Supplement

    Metagenics Releases Consumer Survey on Menopausal Support Supplement

    Culturelle Probiotics Launches Women’s Health Awareness Campaign

    Women's Health Brand O Positiv Launches Essentials Line of Supplements
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    Xsto Solutions

    Sabinsa Corporation

    CoQ10 Association

    Bioenergy Life Science, Inc. (BLS)

    Applied Food Sciences, Inc.
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    Xsto Solutions

    Sabinsa Corporation

    CoQ10 Association

    Bioenergy Life Science, Inc. (BLS)

    Applied Food Sciences, Inc.
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Online Exclusives

    Cognitive Health Benefits Found for Older Adults with Multivitamin/Mineral Supplementation

    Review of COSMOS data suggested that three years of MVM supplementation reduced cognitive aging by 1.8 years compared to baseline.

    Cognitive Health Benefits Found for Older Adults with Multivitamin/Mineral Supplementation
    By Mike Montemarano, Associate Editor09.19.22
    According to ancillary study of data from the COSMOS (Cocoa Supplement and Multivitamin Outcomes) Study, called COSMOS-Mind, daily supplementation with a multivitamin/mineral supplement may lead to benefits in cognition in older adults. This study, conducted by Wake Forest University School of Medicine in collaboration with Brigham and Women’s Hospital, was published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association.

    COSMOS is a large-scale, longitudinal study involving 10,719 participants, which assessed primary outcomes related to cardiovascular disease and cardiovascular mortality in relation to the use of a multivitamin/mineral supplement, Centrum Silver, and a cocoa extract standardized to 500 mg/day of flavanols, similar to Mars’ branded supplement CocoaVia Cardio Health. Groups were randomized to receive either a placebo, a cocoa extract, a multivitamin/mineral supplement, or both a cocoa extract and multivitamin/mineral.

    In the present study, which tracked data from 2,262 participants with a mean age of 73 years old, participants took part in standardized tests including the Telephone Interview of Cognitive Status, World List and Story Recall, Oral Trail-making, Verbal Fluency, Number Span, and Digit Ordering tests.

    “Identifying a safe, affordable, and accessible intervention to protect cognitive function against decline in older adults is a pressing public health priority,” the authors wrote. A subclass of flavonoids called flavanols, which are found in cocoa, are thought to have the potential to slow cognitive decline through improved cerebral vasodilation, blood flow, perfusion, and angiogenesis. Recent research reviews suggest that memory and executive function tend to benefit the most from high daily doses of cocoa flavanols.

    “Individual micronutrients and minerals target multiple biologic pathways that support normal body and brain function, and deficiencies in older adults may increase the risk for cognitive decline and dementia,” the authors continued. “Longer-term daily intake of a multivitamin-mineral alone or with other dietary supplements to enhance global cognitive function in older adults has been examined in just one large randomized controlled trial, which included only male physicians. Further study is needed given their widespread use in the general population.”

    Daily multivitamin/mineral supplementation resulted in statistically significant benefits on global cognition, episodic memory, and executive function in older adults compared to placebo, but cocoa extract supplementation did not have any significant interaction with any of the cognitive domains tested.

    Notably, multivitamin/minerals were linked to the greatest cognitive benefit in adults with cardiovascular disease. To estimate the clinical significance of the findings, the researchers modeled treatment-related protection against cognitive aging, and concluded that compared to placebo, 3 years of multivitamin/mineral supplementation slowed cognitive aging by 60%, or by 1.8 years, compared to baseline.

    The only other long-term multivitamin/mineral randomized controlled trial conducted prior to COSMOS was the 12-year Physician’s Health Study II (PHS-II) of older U.S. male physicians that tested whether a daily multivitamin/mineral supplement prevented risk of major cardiovascular disease and cancer, the authors noted; in a cognitive substudy of PHS-II, there were no significant effects on global cognition composite.

    “There are several differences between COSMOS-Mind and PHS-II worth highlighting,” the authors wrote, such as that the cohorts differed on key baseline characteristics. COSMOS was a much more ethnically diverse cohort, compared to PHS-II, which was predominantly white and non-Hispanic male physicians.

    COSMOS-Mind also administered additional tests of executive function and more challenging episodic memory tests than PHS-II. Further, initial cognitive testing didn’t begin until 2.5 years into the intervention period, nearly at the final follow-up assessment time for COSMOS-Mind. “Our data suggest that MVM treatment effects increased from baseline in the first two years and then remained stable between years two and three,” they wrote. “As a result, any early cognitive benefits of MVM in PHS-II would likely have been missed because of their assessment schedule […]”

    Components of the supplements used in each study also differed. COSMOS added lutein and lycopene, and the amounts of vitamins D and K were higher, with lower amounts of vitamin A, iron, magnesium, and copper.

    Realizing the Full Potential of Multivitamins

    This study holds a great deal of promise for a relatively under-examined health role of multivitamins, according to Andrea Wong, senior vice president of scientific and regulatory affairs at the Council for Responsible Nutrition (CRN), and the full potential of multivitamin supplementation has yet to be realized.

    “Research has already established that multivitamins can help to fill nutrient gaps. Beyond this, the Physician’s Health Study II, a large-scale clinical trial, showed an 8% reduction in overall cancer risk in older male physicians who took a daily multivitamin as well as a significant decrease in cataract risk. The COSMOS-Mind study provides evidence that daily multivitamin consumption may benefit cognitive function in older men and women. With further research, the full potential for multivitamins in protecting and enhancing health could be realized.”

    Duffy MacKay, senior vice president of dietary supplements at the Consumer Healthcare Products Association (CHPA) expressed similar enthusiasm about the findings.

    “The promising results of this clinical trial, showing improved global cognition, episodic memory, and executive function in older adults after three years of daily multivitamin-mineral use, provides first-time evidence that dietary supplementation can be effective in helping older consumers protect and improve cognition.”

    Mark Espeland, principal investigator on the COSMOS-Mind trial, is scheduled to speak at CHPA’s Regulatory, Scientific, and Quality Conference Sep. 20-21.

    “While there is no proven prevention or treatment for cognitive decline, we know that science grows in increments,” said MacKay, “and this study is one step toward reinforcing the beneficial role of a safe, accessible, and affordable dietary supplement that can be used to optimize health through self-care.”

    Still, studies with even greater diversity and scope are still needed to draw any conclusions, said Laura Baker, co-principal investigator of the trial. “It’s too early to recommend daily multivitamin supplementation to prevent cognitive decline,” Baker said. “While these preliminary findings are promising, additional research is needed in a larger and more diverse group of people. Also, we still have work to do to better understand why the multivitamin might benefit cognition in older adults.”
    Related Searches
    • Healthy Aging
    • Research
    • Vitamins
    • Cognitive Function
    Related Knowledge Center
    • Vitamins
    • Research
    • Minerals
    • Healthy Aging
    • Cognitive Function
    • Cardiovascular Health
    Suggested For You
    Metagenics Releases Consumer Survey on Menopausal Support Supplement Metagenics Releases Consumer Survey on Menopausal Support Supplement
     Culturelle Probiotics Launches Women’s Health Awareness Campaign Culturelle Probiotics Launches Women’s Health Awareness Campaign
    Women Women's Health Brand O Positiv Launches Essentials Line of Supplements
    Addressing Brain Health and Stress with CognoLipid Addressing Brain Health and Stress with CognoLipid
    SGS SGS
    Prescription Probiotics and Microbiome Modulation Prescription Probiotics and Microbiome Modulation
    dsm-firmenich to Showcase Essential, Desirable, and Sustainable Solutions at SSW dsm-firmenich to Showcase Essential, Desirable, and Sustainable Solutions at SSW
    Supplyside West Event Info Supplyside West Event Info
    Dyna-Tabs, LLC Dyna-Tabs, LLC
    Women of all ages are getting more proactive about their health Women of all ages are getting more proactive about their health
    Video: Natural Products Expo East 2023 in Pictures Video: Natural Products Expo East 2023 in Pictures
    Women in Nutraceuticals Launches Pilot Mentorship Program Women in Nutraceuticals Launches Pilot Mentorship Program
    Probiotix Health Launches New Heart Health Supplement CholBiome Probiotix Health Launches New Heart Health Supplement CholBiome
    Ashwagandha Extract Linked to Mood and Cognitive Benefits in Several New Studies Ashwagandha Extract Linked to Mood and Cognitive Benefits in Several New Studies
    Clinical Trial Shows Long-Term Joint Health Benefits of PLT’s Boswellia Serrata Extract Clinical Trial Shows Long-Term Joint Health Benefits of PLT’s Boswellia Serrata Extract

    Related Breaking News

    • Breaking News | Dietary Supplements | Herbs & Botanicals | Products | Women's Health
      Metagenics Releases Consumer Survey on Menopausal Support Supplement

      Metagenics Releases Consumer Survey on Menopausal Support Supplement

      Hundreds of women reported that Estrovera, a non-hormonal rhubarb extract, improved hot flashes, sleep disturbances, and symptom severity.
      09.29.23

    • Breaking News | Dietary Supplements | Healthcare Trends | Industry & Market News | Women's Health
       Culturelle Probiotics Launches Women’s Health Awareness Campaign

      Culturelle Probiotics Launches Women’s Health Awareness Campaign

      The Close the Gap campaign will feature three physicians who will promote health literacy, policy changes, and advocacy in the medical community.
      09.29.23

    • Breaking News | Dietary Supplements | Herbs & Botanicals | Products | Vitamins | Women's Health
      Women

      Women's Health Brand O Positiv Launches Essentials Line of Supplements

      The new line includes formulations of iron and vitamin C, milk thistle, L theanine, and a mushroom super blend.
      09.29.23


    • Cognitive Function | Dietary Supplements | Fatty Acids | Healthcare Trends | Healthy Aging | Research
      Addressing Brain Health and Stress with CognoLipid

      Addressing Brain Health and Stress with CognoLipid

      Ilan Perry from Lipogen discusses research and formulation for nourishing the brain and enhancing wellbeing.
      By Sheldon Baker 09.29.23

    • SGS

      SGS

      ...
      Michelle Lee, Marketing Analyst 09.28.23

    Loading, Please Wait..
    Trending
    • Soviets Took Probiotics To The Next Level
    • Todd Spear Joins Protein Research As VP Of Sales And Marketing
    • Growing Mushrooms At Home With Mistercap, Wiz Khalifa
    • New Technology Converts Sugar In Juice To Fiber
    Breaking News
    • D2C Supplement Brand Launches Blood Sugar Support Supplement, Gluco-Control
    • Natrol Launches First Non-Melatonin Sleep Supplement
    • Metagenics Releases Consumer Survey on Menopausal Support Supplement
    • Culturelle Probiotics Launches Women’s Health Awareness Campaign
    • Women's Health Brand O Positiv Launches Essentials Line of Supplements
    View Breaking News >
    CURRENT ISSUE

    September 2023

    • A Clearer Path to Weight Management: The Ozempic Factor
    • Under Pressure: Stress and Mental Health Have Taken Center Stage
    • Sustainable Business Development: Principles and Strategies for Progress
    • BIOHM Health Targets ‘Digestive Plaque’ with Probiotic, Fungus, and Enzyme Formula
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    D2C Supplement Brand Launches Blood Sugar Support Supplement, Gluco-Control
    Natrol Launches First Non-Melatonin Sleep Supplement
    Metagenics Releases Consumer Survey on Menopausal Support Supplement
    Coatings World

    Latest Breaking News From Coatings World

    BASF Donates $5,000 to High School STEAM Education Programs in Chattanooga Area
    Coating Additives Market Worth $10.5B by 2028: MarketsandMarkets
    California Sports Surfaces Celebrates 70 Years
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    MPO's Most-Read Stories This Week—Sept. 30
    Dentsply Sirona Names Former NuVasive CEO Lucier as Chairman
    SeaStar Medical Gets Breakthrough Nod for Selective Cytopheretic Device
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Univercells Expands into the U.S. With New Offices in Andover, MA
    Evecxia Therapeutics, Quotient Sciences Complete Clinical Milestone for Depression Treatment
    Ionis, Roche Partner on RNA-targeted Programs for AD and HD
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    ScentAir Debuts Room Sprays & More
    African Pride Launches On-Campus Activations
    Sharper Image Debuts Revel Hair Tools
    Happi

    Latest Breaking News From Happi

    Hair Searches in the US Change ‘Coarse’ with Growing Demand for Textured Hair Solutions
    Boss Bottled Celebrates 25th Anniversary
    In the Case of Efficacious Cosmetic Buys, Cost is Not A Factor Says Mintel
    Ink World

    Latest Breaking News From Ink World

    W+D to Premiere i-Jet 3 Inkjet at Printing United
    MicroDynamics, All Printing Resources Partner to Represent Veritas
    Weekly Recap: Wikoff Color, BASF, Latin America Top This Week’s Stories
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    TLMI's LLT grows, Labelexpo Europe details big numbers and more
    SABIC and partners launch bio-based IML solution for food packaging
    tesa completes expansion of Michigan manufacturing facility
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Weekly Recap: Thomas Receives INDA Lifetime Technical Service Award, ExxonMobil Works with JL Goor
    Greentech Introduces Air Filter with Advanced Odor Elimination
    Ontex Divests Pakistan Operations to ASAIA Holding
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    ODT's Most-Read Stories This Week—Sept. 30
    Lazurite Adds Benchmark Medical as a Distributor for its ArthroFree Wireless Camera System
    ChitogenX Granted New U.S., Canadian ORTHO-R Patent
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Weekly Recap: Mergers and Acquisitions, First Solar Top This Week’s Stories
    Jabil Posts Fourth Quarter, Fiscal Year 2023 Results
    Ink-Borne ‘Chiplets’ Could Lead to Printable Displays, Electronics and More

    Copyright © 2023 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login