In the three decades since landmark legislation framed the marketplace, dietary supplements have proliferated, offering consumers an expanding menu of products.
After a treatment period, dogs which received the probiotic had improved short-chain fatty acid content, microbiome composition, and functional metagenome.
ZenGut, sourced from a unique strain of microalgae, was evidenced in a recent study to improve GI comfort, mood, mental well-being, and microbiota composition.
Gateway Health Sciences’ Dichrostachys glomerata extract was associated with greater weight loss, reduced food cravings, and improved mood compared to placebo.
Brands have runway to build on traditional, familiar ingredients like protein and probiotics to support modern health issues like digestion, mood, sleep, etc.
By Julian Mellentin, New Nutrition Business10.07.24
Without more resources, FDA can’t conduct enough inspections to get an accurate picture of the marketplace, highlighting the importance of self-regulation.
Two patented botanical extracts were associated with significant increases in GLP-1 blood levels and significant weight loss in 90 overweight/obese subjects.
The global retailer launched a new house brand, and partnered with several pet care brands to offer products designed to support the health of dogs and cats.
The yeast-derived, human-equivalent lactoferrin ingredient is formulated to digest similarly to human lactoferrin, compared to a bovine-sourced counterpart.
The new probiotic products, Pathways Support and Mood Support, were studied in people with autism spectrum disorder by Arizona State University researchers.
The review addresses clinical studies on the botanical formulas’ effects on gut motility, microbioal balance, inflammation, and overall digestive well-being.
This versatile ingredient has been clinically studied for safety, quality, and stability, offering manufacturers an efficacious product with reliable supply.
At the 12th annual Legal, Regulatory, and Compliance Forum on Dietary Supplements, FDA and FTC officials, and lawyers discussed a grab bag of hot topics.
The former Walmart lead e-commerce counsel specialized in helping clients create user experiences that meet advertising, marketing, and privacy requirements.
The blend of rosemary, olive leaves, lemon verbena, and Japanese pagoda tree was linked to improved physiological measures of scalp health after 12 weeks.
The brief continued to argue that a preliminary injunction should prevent New York’s supplement age restriction from going into effect until the lawsuit ends.
Collagen, pet nutrition, sports nutrition, beauty-from-within, and biotics products will see the biggest shake-ups in the coming year, the company projects.
The initiative will focus on PLT’s lineup of disruptive, experiential product development concepts, which meet stringent quality and efficacy standards.
The blend of vitamins, minerals, and botanicals was associated with a 30-50% faster rate of eliminating alcohol from the body, according to the company.
Learn about HMB’s benefits for muscle strength, market insights, and supplement formulation. This leucine metabolite is key for muscle health and performance.
While the studies await publication, new findings examined aged garlic extract in cystic fibrosis, aerobic fitness, cognition, circulation, and oral health.
The U.S. Chamber of Commerce, Consumer Healthcare Products Association, Food Marketplace Inc., and the National Association of Chain Drug Stores voiced support.
The appeal challenges interpretations which led to the recent U.S. District Court decision to let the law go into effect ahead of the lawsuit’s conclusion.
The new products are designed to support common side effects like digestive issues, loss of muscle mass and skin elasticity, and changes in blood sugar levels.
Our most-viewed stories in April included coverage of Amazon's new policy for dietary supplement sellers, Goli's acquisition, the beauty market, and more.
Can the agency better ensure product quality and safety without adding costs, stifling innovation, and constraining access to potentially beneficial products?
The recognition of women’s unique health needs and the concerted efforts to address them mark a significant shift in both culture and scientific endeavors.
By Melanie Bush, VP of Science & Research, Artemis International05.09.24
Probiotics customized to the individual’s gut microbiome and diet appeared to have efficacy in moderately improving cognitive and gastrointestinal problems.
A new House bill would amend the Food, Drug, and Cosmetic Act to grant FDA more authority against products that don't meet the definition of dietary supplement.
In addition to stricter testing requirements, all certificates of authenticity must come directly from third-party companies partnered with the retailer.
The latest of what will be several guidance documents on the NDI process provides updates on the agency’s proposed method to handle proprietary information.
The upcycled prebiotic fiber’s complex structure led to consistent fermentation characteristics and the production of short-chain fatty acids like propionate.
Karallief’s KaraShield botanical blend was associated with reduced frequency and severity of URT symptoms, greater serum IgG, and lower markers of inflammation.
The product license allows finished products to be marketed with claims relevant to liver, cardiovascular, and gut health, as well as blood glucose and stress.
For elite athletes, active lifestylers, and those in the golden years, the supplement market offers compelling options to support strength and mobility.
Move Nutrition Network survey of dietitians, nutritionists, and trainers reveals opportunity for suppliers and brands to reach a growing consumer base.
Liposomal encapsulation is a nascent technology in the supplements space, and proving liposomes were created requires a battery of technical, expensive tests.
Taking the complex of Sphaeranthus indicus and Mangifera indica extracts led to significant improvements in functional measures of strength in a clinical study.
The company plans to expand its carbon-neutral range of ingredients, offset emissions with sequestration projects, and engage in social impact projects.
Foods, drinks, and supplements fortified with phytonutrients can help address the side effects of hustle culture, screen addiction, and sedentary living.
By Melanie Bush, VP of Science & Research, Artemis International02.12.24
Our most-viewed stories in January included Amazon's warning letter from FDA, economically-motivated adulteration in botanicals, and supplement trends to watch.
The agency issued a warning about “Neptune’s Fix” supplements, and all others containing the substance, which can serious, potentially lethal side effects.
An analysis co-authored by STRIPED's director estimated the prevalence of “diet pill,” laxative, and diuretic use across adolescent populations in 90 studies.
The agency found that several “tejocote” supplements were adulterated with the toxic botanical, following a similar investigation in September of last year.
The European Commission approved of 3-fucosyllactose as a novel food ingredient, marking a milestone for improving market access of a broader range of HMOs.
The first-of-its-kind state bill, which bans the sale of “weight loss” and “muscle building” supplements to minors, is slated to go into effect in April 2024.
The coalition of CBD stakeholders plans to advocate for CBD to be regulated as a dietary ingredient with a set of unique testing and labeling standards.
Consumers are focused on wellness throughout their lives, aiming to proactively address concerns related to joint health/mobility, blood sugar, and more.
There’s plenty of research in the field of nutritional neuroscience to support structure-function claims, according to researcher Douglas Kalman, PhD, RD.
Each 12-ounce can contains one billion live probiotic cultures, three grams of prebiotic fiber from acacia, and postbiotics for gut health and immune support.
Due to “competing priorities,” the agency provided no clarification on how it interprets the provision of DSHEA which defines drugs versus dietary ingredients.
The study conducted by MDbio in partnership with Radicle Science found improvements in measure of sleep, stress, and anxiety in a population of 620 adults.
Young people in particular are hungry for health benefits from food. As nutrition ‘rules’ change and need-states evolve, new business opportunities emerge.
By Julian Mellentin, New Nutrition Business11.01.23
The ingredient, standardized to thymoquinone and low free fatty acid content, is classified as a novel food to be sold in dietary supplements in the country.
The collaboration aims to bring products to market that combine and enhance the effectiveness of botanical extracts and ingredients from both companies.
Verdure Sciences’ Witholytin, standardized to 1.5% withanolides, led to 45.8% and 38.6% improvements in the Chalder Fatigue Scale and Perceived Stress Scale.
In addition to a long list of ingredients to learn about, representatives will be on hand to discuss the history of commitment toward environmental stewardship.
Shortly after the approval of the HMOs 2’-FL and LNnT, global suppliers dsm-firmenich and IFF were among the first companies to receive individual clearance.
Convenient product formats like gummies and beverages offer broad appeal, while multifunctional dietary supplement formulas offer value for varied need states.
Vitaquest International's new facility comes with fluidized bed process technologies enabling particle and powder engineering for foods and dietary supplements.
The new multi-ingredient product by Touchstone Essentials contains a plant-based enzyme evidenced to convert glucose molecules from food into resistant starch.
The guidance, issued this year is a departure from common marketing practice of dietary supplements and food, and misrepresents the state of the law, CRN said.
The trade organization said the notices issued earlier this year were inconsistent with regulatory practice, and unenforceable because they violate due process.
Those who supplemented with Probiotical’s Bifizen had improved moods sustained through a washout period, as well as increases in circulating serotonin.
The prebiotic fiber received approval for eight claims in total, and unrestricted use in dietary supplements regulated by the Therapeutic Goods Administration.
Supplementation with a strain called L. plantarum HEAL9 by Probi resulted in improved test performance in 129 healthy individuals with self-reported stress.
Our most-viewed stories in July included a proposed bill to cover supplement costs under HSAs/FSA, FDA inaction on NMN, the herbal supplements market and more.
Following an update from the agency, the trade association characterized the agency’s plan as ‘pulling back’ on its responsibility to regulate supplements.
The gaming industry has swelled to exorbitant numbers generating more revenue than digital music, film, video streaming, the NFL and the Olympics combined.
As a global player in oleochemicals and phytonutrients, KLK OLEO/ Davos Life Science offers an array of high quality, natural and sustainable products.
The company will showcase strains and capabilities in areas such as gut health, women’s health, the gut-brain axis, and delivery and dosage technologies.
The Founder & Executive Director of the American Botanical Council reflects on nearly 50 years of industry experience and the advancement of ABC's mission.
Learn about the need for more eye health solutions, the science supporting EYEMUSE™, opportunities for its application in dietary supplements, and more.
While variety in food patterns implies diverse nutrient needs, few of hundreds of prenatal supplements assessed were suitable for 90% of pregnant participants.
The two companies will use Forager, Brightseed’s artificial intelligence program, to analyze molecular interactions between dietary plants and gut microbes.
A bill which offered a slate of protections for people with eating disorders was amended in order to remove dietary supplement restrictions from the equation.
Elizondo joins some of the most promising leaders under the age of 40 who are committed to serving society and are launching initiatives to drive social change.
Those with higher blood erythritol levels were shown to have elevated risk of experiencing a major adverse cardiac event such as heart attack, stroke or death.
Compared to a standard caffeine supplement, Nutriventia’s CaffXtend resulted in a longer peak time, and significant improvements in self-reported effects.
Guidance includes recommendations on how to analyze hazards, evaluate a supplier’s performance and risk, and conduct appropriate verification activities.
This year-long reference of global companies supplying nutraceutical ingredients, products, and services is the starting place for all your buying needs.
RFI’s proprietary FermaPro solution can ferment any dry material—grains, grasses, seeds, botanicals, vegetables, and fruits—using bacterial or yeast cultures.
President and CEO of the Council of Responsible Nutrition discussed the industry’s need to strengthen communications, self-regulation, and transparency.
Prinova is a one-stop-shop for 2,000+ ingredients, premixes, and flavors; and it has boots on the ground to maneuver around today’s supply chain pitfalls.
Morus alba has a long history of safe use in TCM, and the evidence implicating this herb with the death of a Congressman’s wife is inconclusive at best.
Low Dog is an expert in dietary supplements, integrative medicine, and women’s health, and has been in the field of natural medicine for over 30 years.
Proposed legislation aims to create a new agency that would assume responsibilities for the regulation of food and dietary supplements currently held by FDA.
By Michael McGuffin, President, American Herbal Products Association (AHPA)09.13.22
Company operates according to current Good Manufacturing Practices under 21 CFR part 111 and part 117, with an FDA-compliant fulfillment facility in Reno, NV.
According to product recall reports, just a portion of products containing illegal ingredients were recalled following the issuance of warning letters.
With consumers prioritizing clean label appeal, producers are met with new opportunities to provide products that promote closer-to-nature ingredients.
A review of 71 studies found a dose-dependent relationship between omega-3s and blood pressure reductions, most significant for those with hypertension.
If a claim describes the substantiated role a nutrient or dietary ingredient plays in the body, plaintiffs cannot survive a motion for summary judgment.
By Todd Harrison, Partner; Richard Starr, Associate; and Olisa Onyiuke, Associate, Venable06.02.22
With fewer recalls than conventional foods, drugs, animal products and medical devices, supplements could be considered the safest class of goods FDA regulates.
By Michael McGuffin, President, American Herbal Products Association (AHPA)06.02.22
Amnesty for late NDI notifications is intended to encourage manufacturers and distributors to correct past failures while collecting safety data, FDA said.
The new Master’s degree program will equip working professionals with regulatory compliance and nutrition guidelines relevant to the supplements industry.
Gummies, beverages, stick packs, and snack-like products are on-trend, but brands have a lot to consider in terms of formulation and regulatory compliance.
Industry should view both proposed legislation and arguments against it with a critical eye, but let’s address legitimate concerns while dismissing strawmen.
By Steve Mister, President & CEO, Council for Responsible Nutrition04.26.22
Sen. Dick Durbin (D-IL) and Sen. Mike Braun (R-IN) introduced a bill that would require dietary supplement manufacturers to file product information with FDA.
Utah’s longest-serving Senator was known for working across the aisle, authoring or coauthoring some of the most consequential laws of the past half century.
Plaintiffs are monitoring whether a company abides by all relevant FDA regulations, so it’s important to understand requirements and confirm disclaimers.
By Todd Harrison, Partner; Kristen Klesh, Counsel; Olisa Onyiuke, Associate; and Melanie English, Associate Venable04.14.22
Technology that can track a sequence of transactions helps build trust among stakeholders along the supply chain, as well as between consumers and brands.
By Robert Galaza, CEO, TruTrace Technologies04.14.22
The U.S. Food and Drug Administration is prioritizing multiple ways to regulate the dietary supplements industry in its request for an $8.4 billion budget.
Adding CBD, a naturally anti-inflammatory ingredient, to the base 0.2% retinol solution, maintains the anti-aging properties, but with reduced side effects.
By Julius Few, MD; Michael Lee, MD; Alec Semersky; Emily Mariscal, LE; and Ginny Vachon, PhD04.07.22
At Expo West, research experts from ChildLife Essentials discussed the role of nutraceuticals in the interplay between the gut, cognition, and immunity.
The patent-pending technology allows for sugar and sugar-free options, both compliant with USDA organic standards and international organic requirements.
Most audits have been conducted on the harvests of other Boswellia species, leading to some confusion about the species used in dietary supplements and foods.
Following a review of the evidence, FDA now supports three types of claims on the research, which it still considers to be “inconsistent and inconclusive.”
After issuing warning letters to companies claiming that NAC is excluded as a dietary ingredient, the agency's response to citizen petitions is still tentative.
The barley fiber and protein ingredient company backed by Anheuser-Busch InBev will introduce sustainable ingredients that set high conservation benchmarks.
The range of three products features hobamine, a novel ingredient tied to DNA protection and antioxidant activity, alongside several other emerging ingredients.
Layn Natural Ingredients' TruGro, a complex of polyphenol-rich green tea extracts and compounds naturally occurring in green tea leaves, is NASC-certified.
Defining standard terminology is important to the hemp and CBD industries for regulations, consumer understanding, and product manufacturing and marketing.
Company specializes in analytical chemistry and microbiology testing for pharma, nutraceutical, dietary supplement, cosmetic, and cannabis/CBD industries.
Updates were designed to make it easier to navigate the database through more streamlined search functions with the ability to customize search results.
Wommack, who currently serves as CRN’s senior vice president, will follow the foundation’s plan to prioritize access to nutritional products and education.
Euglena gracilie from Solabia-Algatech Nutrition produced through fermentation technology to deliver high beta-glucan plus protein, vitamins, minerals and more.
Pharmactive’s Affron appeared to attenuate the psychological symptoms of menopause, such as hot flushes, night sweats, mood changes, and sleep disturbances.
FDA raised objections to the use of N-acetylcysteine in supplements in Dec. 2020, and since, Amazon has pulled all NAC-containing products from its platform.
Focus centered around the GRAS and NDI processes, the prospects of a mandatory product listing, how health claims will be handled in the future, and more.
The bipartisan legislation, the Hemp Access and Consumer Safety Act of 2021, was introduced by Senators Ron Wyden, Jeff Merkley (both D-OR) and Rand Paul (R-KY)
With young consumers and an aging population pursuing healthy, active lifestyles, opportunities to offer clinically supported products will continue to emerge.
The cosmeceutical ingredient has received a Certificate of Functional Ingredient for Functional Health Foods from the Ministry of Food and Drug Safety.
500 mg of the water-soluble turmeric extract improved joint range of motion, soreness, and markers of inflammation and oxidative stress following exercise.
The Botanical Adulterants Prevention Program’s latest installation includes lab data from 532 commercial elderberry samples, evidencing authenticity problems.
Rob Wildman, Safety Call International, Herbalife Nutrition, Naturate, Indena S.p.A, and Tony Hayes (posthumously) were awarded for outstanding contributions.
While the agency has not specifically confirmed it, dietary supplements were not mentioned in a list of manufacturers required to enhance traceability measures.
Canadian natural products company SierraSil Health Inc is on a mission to help one million plus people feel empowered to lead natural, healthy, active lives.
The third-party testing organization will also expand its dietary supplement GMP program to include manufacturers of cosmetics, personal care, and over-the-counter products.
FDA currently prohibits the use of NAC as a dietary supplement, and is concerned about a proposal for HHS to review certain regulations or let them expire.
Some practitioners were not selling or promoting products, they were simply suggesting certain natural substances might offer benefits in improving resilience.
With support from clinical findings and increased consumer demand, elderberry is a top ingredient in the dietary supplement and natural products industry.
By Melanie Bush, Director of Science, Artemis International, Inc.10.01.20
The role pets play in U.S. households has been redefined, and more people are buying products designed to support a long and healthy life for their furry pals.
By Kevin Owen, PhD, Global Business Development, Companion Animals Lonza Consumer Health & Nutrition09.09.19
A total of 14 staff members are specifically trained in implementing the 21 CFR part 117 regulations, covering all of the company’s manufacturing facilities.
Continued research supporting product use for specific conditions will help grow consumer awareness and offer long-lasting, added value to the category.
Peter Wojewnik is director of business development at Dicentra, a leading scientific and regulatory consulting firm based in Toronto with specialized expertise in the areas of natural health products, dietary supplements, OTCs, foods and cosmetics.