In the three decades since landmark legislation framed the marketplace, dietary supplements have proliferated, offering consumers an expanding menu of products.
After a treatment period, dogs which received the probiotic had improved short-chain fatty acid content, microbiome composition, and functional metagenome.
The court entered judgment against JT Best Deals LLC for trademark infringement and tortious interference of existing contracts and business relationships.
Gateway Health Sciences’ Dichrostachys glomerata extract was associated with greater weight loss, reduced food cravings, and improved mood compared to placebo.
Brands have runway to build on traditional, familiar ingredients like protein and probiotics to support modern health issues like digestion, mood, sleep, etc.
By Julian Mellentin, New Nutrition Business10.07.24
Without more resources, FDA can’t conduct enough inspections to get an accurate picture of the marketplace, highlighting the importance of self-regulation.
Two patented botanical extracts were associated with significant increases in GLP-1 blood levels and significant weight loss in 90 overweight/obese subjects.
The acquisition includes dsm-firmenich’s fish oil business for foods, beverages, supplements, and pharmaceuticals, and the MEG-3 brand and its facilities.
The global retailer launched a new house brand, and partnered with several pet care brands to offer products designed to support the health of dogs and cats.
Private label brand PharmaLinea’s vitamin and nucleotide complex appeared to offer greater benefit than placebo in a population undergoing physical therapy.
The yeast-derived, human-equivalent lactoferrin ingredient is formulated to digest similarly to human lactoferrin, compared to a bovine-sourced counterpart.
The cannabinoid was found to improve sleep quality with no side effects in 1,000 people, at levels more significant than standard-dose melatonin supplements.
Forty peri- and early post-menopausal subjects who took blackcurrant powder for 6 months had improvements in whole-body bone density and related biomarkers.
The review addresses clinical studies on the botanical formulas’ effects on gut motility, microbioal balance, inflammation, and overall digestive well-being.
This versatile ingredient has been clinically studied for safety, quality, and stability, offering manufacturers an efficacious product with reliable supply.
At the 12th annual Legal, Regulatory, and Compliance Forum on Dietary Supplements, FDA and FTC officials, and lawyers discussed a grab bag of hot topics.
The former Walmart lead e-commerce counsel specialized in helping clients create user experiences that meet advertising, marketing, and privacy requirements.
The brief continued to argue that a preliminary injunction should prevent New York’s supplement age restriction from going into effect until the lawsuit ends.
Collagen, pet nutrition, sports nutrition, beauty-from-within, and biotics products will see the biggest shake-ups in the coming year, the company projects.
The live strains and their postbiotic forms are clinically evidenced to support an oral microbiome balance, measures of dental health, and fresh breath.
The initiative will focus on PLT’s lineup of disruptive, experiential product development concepts, which meet stringent quality and efficacy standards.
The blend of vitamins, minerals, and botanicals was associated with a 30-50% faster rate of eliminating alcohol from the body, according to the company.
Learn about HMB’s benefits for muscle strength, market insights, and supplement formulation. This leucine metabolite is key for muscle health and performance.
The new test kit, available to healthcare practitioners, utilizes dried blood spot assay technology, which Chromadex reports is most suitable for accuracy.
While the studies await publication, new findings examined aged garlic extract in cystic fibrosis, aerobic fitness, cognition, circulation, and oral health.
The U.S. Chamber of Commerce, Consumer Healthcare Products Association, Food Marketplace Inc., and the National Association of Chain Drug Stores voiced support.
Proprietary supplement brands The Vitamin Shoppe, Vthrive The Vitamin Shoppe, BodyTech, and BodyTech Elite, are now available in over 180 countries via iHerb.
The appeal challenges interpretations which led to the recent U.S. District Court decision to let the law go into effect ahead of the lawsuit’s conclusion.
The new products are designed to support common side effects like digestive issues, loss of muscle mass and skin elasticity, and changes in blood sugar levels.
Gencor’s Levagen+ was associated with a 17% greater improvement in lower body power, and 5% greater improvement in isometric strength, compared to placebo.
The range of symptoms and health needs experienced by women at this life stage represents one of the most important white spaces in today’s marketplace.
Diverse cultivation techniques, standardized testing methods, and unified labeling standards will help strengthen product integrity in a maturing market.
By Julie Daoust, PhD, Chief Scientific Officer, M2 Ingredients / Om Mushroom Superfood06.03.24
The nonprofit group works with over 1,200 local organizations and governments to reach more than 72 million women and children in 65 countries each year.
Our most-viewed stories in April included coverage of Amazon's new policy for dietary supplement sellers, Goli's acquisition, the beauty market, and more.
Can the agency better ensure product quality and safety without adding costs, stifling innovation, and constraining access to potentially beneficial products?
The recognition of women’s unique health needs and the concerted efforts to address them mark a significant shift in both culture and scientific endeavors.
By Melanie Bush, VP of Science & Research, Artemis International05.09.24
Probiotics customized to the individual’s gut microbiome and diet appeared to have efficacy in moderately improving cognitive and gastrointestinal problems.
The certificate audits the supply chain from seed to oil, for environmental protection, waste and energy management, social responsibility, and compliance.
A new House bill would amend the Food, Drug, and Cosmetic Act to grant FDA more authority against products that don't meet the definition of dietary supplement.
Givaudan’s ThinkBlue was found to support cognitive function greater than placebo in two separate studies involving a total of 72 healthy older adults.
In addition to stricter testing requirements, all certificates of authenticity must come directly from third-party companies partnered with the retailer.
With a sizable portion of U.S. consumers taking new weight loss drugs, experts discussed ramifications for marketers, brands, and healthcare practitioners.
The latest of what will be several guidance documents on the NDI process provides updates on the agency’s proposed method to handle proprietary information.
For elite athletes, active lifestylers, and those in the golden years, the supplement market offers compelling options to support strength and mobility.
Move Nutrition Network survey of dietitians, nutritionists, and trainers reveals opportunity for suppliers and brands to reach a growing consumer base.
Liposomal encapsulation is a nascent technology in the supplements space, and proving liposomes were created requires a battery of technical, expensive tests.
Foods, drinks, and supplements fortified with phytonutrients can help address the side effects of hustle culture, screen addiction, and sedentary living.
By Melanie Bush, VP of Science & Research, Artemis International02.12.24
In 269,229 senior UK Biobank participants, those who used vitamin D supplements and those with high blood concentrations were less likely to have dementia.
Our most-viewed stories in January included Amazon's warning letter from FDA, economically-motivated adulteration in botanicals, and supplement trends to watch.
The agency issued a warning about “Neptune’s Fix” supplements, and all others containing the substance, which can serious, potentially lethal side effects.
An analysis co-authored by STRIPED's director estimated the prevalence of “diet pill,” laxative, and diuretic use across adolescent populations in 90 studies.
The agency found that several “tejocote” supplements were adulterated with the toxic botanical, following a similar investigation in September of last year.
Athletes who supplemented with prebiotics and a probiotic blend called Herbaferm saw positive changes in several anthropometric measures compared to placebo.
Qualia Senolytic, a nine-ingredient formula designed to support the body in eliminating senescent cells, improved self-reported joint function within six months
Despite initial negative findings, a secondary analysis of the large-scale study found cocoa extract improved cognition for those with poor diet at baseline.
While the study didn't include calcium supplementation, it was nonetheless "striking" that vitamin D alone made no difference, according to the authors.
The European Commission approved of 3-fucosyllactose as a novel food ingredient, marking a milestone for improving market access of a broader range of HMOs.
The first-of-its-kind state bill, which bans the sale of “weight loss” and “muscle building” supplements to minors, is slated to go into effect in April 2024.
The coalition of CBD stakeholders plans to advocate for CBD to be regulated as a dietary ingredient with a set of unique testing and labeling standards.
Consumers are focused on wellness throughout their lives, aiming to proactively address concerns related to joint health/mobility, blood sugar, and more.
There’s plenty of research in the field of nutritional neuroscience to support structure-function claims, according to researcher Douglas Kalman, PhD, RD.
Each 12-ounce can contains one billion live probiotic cultures, three grams of prebiotic fiber from acacia, and postbiotics for gut health and immune support.
Due to “competing priorities,” the agency provided no clarification on how it interprets the provision of DSHEA which defines drugs versus dietary ingredients.
Young people in particular are hungry for health benefits from food. As nutrition ‘rules’ change and need-states evolve, new business opportunities emerge.
By Julian Mellentin, New Nutrition Business11.01.23
The ingredient, standardized to thymoquinone and low free fatty acid content, is classified as a novel food to be sold in dietary supplements in the country.
The collaboration aims to bring products to market that combine and enhance the effectiveness of botanical extracts and ingredients from both companies.
The microencapsulated iron ingredient reduces reactivity in the mouth and digestive tract, improving digestibility and taste, according to the company.
The turmeric extract, standardized to 95% curcuminoids, is fully water dispersible, and three times more potent than competing extracts, the company reports.
Proactive strategies to improve bone density should be an important concept in healthy aging product development, notes vitamin K2 supplier Gnosis by Lesaffre.
Convenient product formats like gummies and beverages offer broad appeal, while multifunctional dietary supplement formulas offer value for varied need states.
Vitaquest International's new facility comes with fluidized bed process technologies enabling particle and powder engineering for foods and dietary supplements.
The guidance, issued this year is a departure from common marketing practice of dietary supplements and food, and misrepresents the state of the law, CRN said.
The trade organization said the notices issued earlier this year were inconsistent with regulatory practice, and unenforceable because they violate due process.
The formulation contains Lactobacillus plantarum LPLDL, K2Vital Delta from Kappa Bioscience, and thiamine, a form of vitamin B1 with an EFSA heart health claim.
Those who supplemented with Probiotical’s Bifizen had improved moods sustained through a washout period, as well as increases in circulating serotonin.
The prebiotic fiber received approval for eight claims in total, and unrestricted use in dietary supplements regulated by the Therapeutic Goods Administration.
Supplementation with a strain called L. plantarum HEAL9 by Probi resulted in improved test performance in 129 healthy individuals with self-reported stress.
Our most-viewed stories in July included a proposed bill to cover supplement costs under HSAs/FSA, FDA inaction on NMN, the herbal supplements market and more.
Following an update from the agency, the trade association characterized the agency’s plan as ‘pulling back’ on its responsibility to regulate supplements.
Evidence mounts for the health benefits of PACs, and future innovations in quality and testing will improve efficacy while revealing other health benefits.
The gaming industry has swelled to exorbitant numbers generating more revenue than digital music, film, video streaming, the NFL and the Olympics combined.
The company will showcase strains and capabilities in areas such as gut health, women’s health, the gut-brain axis, and delivery and dosage technologies.
The Founder & Executive Director of the American Botanical Council reflects on nearly 50 years of industry experience and the advancement of ABC's mission.
Learn about the need for more eye health solutions, the science supporting EYEMUSE™, opportunities for its application in dietary supplements, and more.
While variety in food patterns implies diverse nutrient needs, few of hundreds of prenatal supplements assessed were suitable for 90% of pregnant participants.
The two companies will use Forager, Brightseed’s artificial intelligence program, to analyze molecular interactions between dietary plants and gut microbes.
A bill which offered a slate of protections for people with eating disorders was amended in order to remove dietary supplement restrictions from the equation.
Those with higher blood erythritol levels were shown to have elevated risk of experiencing a major adverse cardiac event such as heart attack, stroke or death.
In over 110,000 subjects, those in the highest quintile for DHA status were 26% less likely to be hospitalized compared to those with the lowest DHA status.
Compared to a standard caffeine supplement, Nutriventia’s CaffXtend resulted in a longer peak time, and significant improvements in self-reported effects.
Guidance includes recommendations on how to analyze hazards, evaluate a supplier’s performance and risk, and conduct appropriate verification activities.
Soluble prebiotic carrot fiber known as RG-I (Rhamnogalacturonan-I) has a dual mode of action to help minimize the impact of everyday health challenges.
President and CEO of the Council of Responsible Nutrition discussed the industry’s need to strengthen communications, self-regulation, and transparency.
Specnova’s NooGandha improved working memory, helped sustain attention, and maintained reaction times, with no sedative effects, in a single 400 mg dose.
Nonprofit focused on increasing female leadership roles, securing funding for women-led businesses, and improving participation in science and research.
Prinova is a one-stop-shop for 2,000+ ingredients, premixes, and flavors; and it has boots on the ground to maneuver around today’s supply chain pitfalls.
Morus alba has a long history of safe use in TCM, and the evidence implicating this herb with the death of a Congressman’s wife is inconclusive at best.
Low Dog is an expert in dietary supplements, integrative medicine, and women’s health, and has been in the field of natural medicine for over 30 years.
Proposed legislation aims to create a new agency that would assume responsibilities for the regulation of food and dietary supplements currently held by FDA.
By Michael McGuffin, President, American Herbal Products Association (AHPA)09.13.22
Company operates according to current Good Manufacturing Practices under 21 CFR part 111 and part 117, with an FDA-compliant fulfillment facility in Reno, NV.
According to product recall reports, just a portion of products containing illegal ingredients were recalled following the issuance of warning letters.
With consumers prioritizing clean label appeal, producers are met with new opportunities to provide products that promote closer-to-nature ingredients.
A review of 71 studies found a dose-dependent relationship between omega-3s and blood pressure reductions, most significant for those with hypertension.
China’s supplement market is growing at double digit levels. Jeff Crowther has the market intel to assist companies in capitalizing on emerging opportunities.
If a claim describes the substantiated role a nutrient or dietary ingredient plays in the body, plaintiffs cannot survive a motion for summary judgment.
By Todd Harrison, Partner; Richard Starr, Associate; and Olisa Onyiuke, Associate, Venable06.02.22
With fewer recalls than conventional foods, drugs, animal products and medical devices, supplements could be considered the safest class of goods FDA regulates.
By Michael McGuffin, President, American Herbal Products Association (AHPA)06.02.22
CTX-II clinical model patent has been used in multiple clinical trials to show NEM eggshell membrane helps protect cartilage in exercising individuals.
Amnesty for late NDI notifications is intended to encourage manufacturers and distributors to correct past failures while collecting safety data, FDA said.
The new Master’s degree program will equip working professionals with regulatory compliance and nutrition guidelines relevant to the supplements industry.
Gummies, beverages, stick packs, and snack-like products are on-trend, but brands have a lot to consider in terms of formulation and regulatory compliance.
Industry should view both proposed legislation and arguments against it with a critical eye, but let’s address legitimate concerns while dismissing strawmen.
By Steve Mister, President & CEO, Council for Responsible Nutrition04.26.22
Sen. Dick Durbin (D-IL) and Sen. Mike Braun (R-IN) introduced a bill that would require dietary supplement manufacturers to file product information with FDA.
Utah’s longest-serving Senator was known for working across the aisle, authoring or coauthoring some of the most consequential laws of the past half century.
Plaintiffs are monitoring whether a company abides by all relevant FDA regulations, so it’s important to understand requirements and confirm disclaimers.
By Todd Harrison, Partner; Kristen Klesh, Counsel; Olisa Onyiuke, Associate; and Melanie English, Associate Venable04.14.22
Technology that can track a sequence of transactions helps build trust among stakeholders along the supply chain, as well as between consumers and brands.
By Robert Galaza, CEO, TruTrace Technologies04.14.22
The U.S. Food and Drug Administration is prioritizing multiple ways to regulate the dietary supplements industry in its request for an $8.4 billion budget.
At Expo West, research experts from ChildLife Essentials discussed the role of nutraceuticals in the interplay between the gut, cognition, and immunity.
The patent-pending technology allows for sugar and sugar-free options, both compliant with USDA organic standards and international organic requirements.
Most audits have been conducted on the harvests of other Boswellia species, leading to some confusion about the species used in dietary supplements and foods.
The study on Monteloeder’s Metabolaid also observed significant improvements in blood lipid profiles, decreases in fat mass, and markers of increased satiety.
However, meta-analysis concluded supplementation with vitamins C, D, or zinc was not associated with mortality benefit among hospitalized COVID-19 patients.
The agency has called into question the amino acid metabolite’s legal status as a dietary ingredient, counter to the opinions of several industry leaders.
Cal2Mag’s ratio has been supported by research suggesting the formulation can reduce arterial calcification risks associated with taking calcium alone.
With B. subtilis DE111 for gut and immune support, bolstered by vitamins C or D, the kids' and adults' varieties are TruBiotics' first foray into gummies.
Based on NHANES data collected from cancer survivors, the authors of a review found that the use of supplements was linked to long-term, cost-effective benefit.
Following a review of the evidence, FDA now supports three types of claims on the research, which it still considers to be “inconsistent and inconclusive.”
A new animal study provides additional primary evidence for a whitepaper by Nature’s Crops, the makers of the omega-3-rich botanical ingredient Ahiflower.
After issuing warning letters to companies claiming that NAC is excluded as a dietary ingredient, the agency's response to citizen petitions is still tentative.
A 16-day regimen of beneficial Lactobacillus strains improved nausea and vomiting, both commonplace issues pregnant women deal with in early pregnancy.
Lycored’s Lumenato was evidenced in a clinical study to boost collagen production, reduce inflammation and oxidative stress, and improve skin appearance.
The barley fiber and protein ingredient company backed by Anheuser-Busch InBev will introduce sustainable ingredients that set high conservation benchmarks.
What we’ve created is truly a unique product built specifically for the supplement industry and the challenges they face when formulating and labeling products.
The range of three products features hobamine, a novel ingredient tied to DNA protection and antioxidant activity, alongside several other emerging ingredients.
Compelling increases in online searches and social media discussions, especially among younger crowds, suggest people want more than just plant-based products.
Layn Natural Ingredients' TruGro, a complex of polyphenol-rich green tea extracts and compounds naturally occurring in green tea leaves, is NASC-certified.
Wommack, who currently serves as CRN’s senior vice president, will follow the foundation’s plan to prioritize access to nutritional products and education.
The role pets play in U.S. households has been redefined, and more people are buying products designed to support a long and healthy life for their furry pals.
By Kevin Owen, PhD, Global Business Development, Companion Animals Lonza Consumer Health & Nutrition09.09.19
FDA reviewed supporting scientific data on the probiotic and has no questions or objections, allowing it to be considered ‘Generally Recognized As Safe.’
A total of 14 staff members are specifically trained in implementing the 21 CFR part 117 regulations, covering all of the company’s manufacturing facilities.
Tom Vierhile is the director of innovation insights for Datamonitor. He has more than 20 years of experience in consumer packaged goods reporting and analysis, much of that with Datamonitor’s product launch analytics database of new products.
Peter Wojewnik is director of business development at Dicentra, a leading scientific and regulatory consulting firm based in Toronto with specialized expertise in the areas of natural health products, dietary supplements, OTCs, foods and cosmetics.
Stratum Nutrition’s parent company, Novus International, Inc. has acquired the IQF Group, a Spanish producer of nutritional additives for the feed industry, as well as a range of carotenoids for foods, beverages and supplements.