Oils are used in pharmaceutical formulations to improve taste, prepare stable suspensions of drugs, add stability to APIs that are sensitive to hydrolysis, and in various other applications. In addition, oils are increasingly being used in formulations today as drug solubilizers, adsorption enhancers and vehicles for lipid based drug delivery, in order to increase the oral bioavailability of poorly soluble drugs. The main challenge in oil-based formulations is converting oily solutions and liquid formulations into compressible solid or semi-solid formulations.
SYLOID® FP silicas are an excellent carrier for converting oils, oily drugs, and drugs in oil solutions into free flowing powders. They can be used as adsorbents in techniques such as solid dispersion, semisolids and in lipid-based technologies such as self-emulsifying drug delivery systems (SEDDS).