• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    Nutraceuticals for Men: Muscle Health and Performance Nutrition

    Aging in Place: Healthy Lifestyles Supplement Science-Based Solutions

    Getting an Edge in Esports: Meeting the Health Needs of Competitive Gamers

    Beyond CBD: Cannabis Compounds Warrant Recognition and More Research

    Leveling Out the Energy Segment for Mainstream, and Rethinking Caffeine
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    Thorne Relaunches Gut Health Test with Microbiome Wipe

    Alkemist Labs Announces Alkemist Assured Seal and Next Generation Transparency Reports

    GC Rieber Foundations Expand Philanthropic Efforts

    Danone Celebrates 10th anniversary of Grant Program for Probiotics Research

    Stratum Nutrition’s Patent Portfolio Grows to Europe and Canada
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    GC Rieber Foundations Expand Philanthropic Efforts

    Danone Celebrates 10th anniversary of Grant Program for Probiotics Research

    Botanical Ingredient MorActive Evidenced to Relieve Back Discomfort

    Cargill’s Stevia Sustainability Program Benchmarked by FSA

    GOED Creates Infographic Highlighting Omega-3 Health Claims Approved in Europe
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    Thorne Relaunches Gut Health Test with Microbiome Wipe

    Alkemist Labs Announces Alkemist Assured Seal and Next Generation Transparency Reports

    GC Rieber Foundations Expand Philanthropic Efforts

    Danone Celebrates 10th anniversary of Grant Program for Probiotics Research

    Stratum Nutrition’s Patent Portfolio Grows to Europe and Canada
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    Thorne Relaunches Gut Health Test with Microbiome Wipe

    Danone Celebrates 10th anniversary of Grant Program for Probiotics Research

    Beyond Raw Launches Concept X Pre-Workout Line

    Botanical Ingredient MorActive Evidenced to Relieve Back Discomfort

    Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    ESHA Research

    PhytoGaia Inc

    Nutrition21, LLC

    Atlantia Clinical Trials

    Aiya America, Inc. (Aiya Matcha)
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    ESHA Research

    PhytoGaia Inc

    Nutrition21, LLC

    Atlantia Clinical Trials

    Aiya America, Inc. (Aiya Matcha)
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Breaking News

    Deficiencies in Vitamins D and K Independently Linked to COVID-19 Severity

    A new study supported by Kappa Bioscience showed that these two vitamins could play independent roles in the disease’s pathogenesis.

    Deficiencies in Vitamins D and K Independently Linked to COVID-19 Severity
    Related CONTENT
    • Stratum Nutrition’s Patent Portfolio Grows to Europe and Canada
    • Beyond Raw Launches Concept X Pre-Workout Line
    • Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission
    • Experts Debate Role of Supplements in Improving Public Health in EU
    • Tocotrienols May Aid Weight Loss and Cognitive Performance, Animal Study Finds
    10.25.21
    Concentrations of both vitamins D and K could play a role in the severity of COVID-19 infections, according to a new independent study supported by Kappa Bioscience, expounding upon previous publications which have observed links between these deficiencies and severe COVID-19. While the trial was preliminary in nature and observational, the results warranted further research investigating preventive measures in larger population sizes, the authors said.
     
    The present study, published in Open Forum Infectious Diseases, examined the influence of both of these vitamins independently on the course of COVID-19 in 100 COVID-19 patients, compared to a control group of 50 people, measuring their vitamin D and vitamin K levels.
     
    Compared to the healthy control group, the authors of the study noted that levels of DP-ucMGP, a biomarker for vitamin K status, was significantly lower in the COVID-19 group.
     
    While across the COVID-19 and control groups, vitamin D levels were not significantly different, vitamin D deficiency experienced the most severe COVID-19 outcomes. Approximately 15% of the COVID-19 group was classified as having a severe case. Vitamin K deficiencies were also strongly associated with vitamin D deficiency.
     
    Specifically, every one-unit increase in DP-ucMGP levels (stronger vitamin K deficiency) nearly doubled the odds of acute critical disease or death, and every one-unit decrease in blood concentrations of vitamin D was associated with greater than three-times the likelihood of severe COVID-19 disease.
     
    The two vitamins have been previously-established to exhibit synergistic benefits to bone and cardiovascular health, but as this is an observational study, no mechanisms of action could be established for the independent, protective benefits that vitamins K and D had in the COVID-19 patients studied. However, the authors of the study proposed that it may have to do with previously-established benefits to calcium metabolism dependent on adequate intakes on both vitamins.
     
    “Put simply, vitamin D enables the production of some key proteins, which paly a role in calcium metabolism. But they are produced in an inactive state, and vitamin K2 is the catalyst that activates them,” Trygve Bergeland, vice president of science at Kappa Bioscience, said. “These proteins mobilize calcium, carrying it away from our arteries and soft tissues, and incorporating it into our bones, where it is needed. In COVID-19, it was shown that patients with low vitamin K status had increased elastic fiber degradation and vascular calcifications. On its own, vitamin K also regulates blood clotting, which seems crucial to prevent thromboembolism, as often observed in more severe COVID-19.”
     
    “Interestingly, both vitamin D and K may display complementary effects on the cytokine storm, thrombosis, and lung damage during COVID-19. Specifically, they display similar inhibitory effects on inhibition of NF-kB and cytokine release, and vitamins D and K appear to work synergistically to help protect against calcification and damage in the lungs,” said Dr. Grace McComsey, MD, FIDSA, vice president of research and associate chief scientific officer at University Hospitals. McComsey is a corresponding author of the study.
     
    “Optimizing vitamins K and D prior to acute COVID-19 infection may help to regulate overwhelming calcification, inflammation, and coagulopathy, which may subsequently lead to improved clinical outcomes,” McComsey continued. “As the long-chain menaquinones, such as K2 MK-7 [a specific form of vitamin K] have an extrahepatic distribution, they possess the capacity to optimize the vitamin K status in tissues that are deficient, however, large preventive clinical trials are needed.”
     
     
    Related Searches
    • Cardiovascular Health
    • Antioxidants
    • Contract Manufacturing
    • Medical Nutrition
    Related Knowledge Center
    • Research
    • Vitamins
    • Antioxidants
    Suggested For You
    Stratum Nutrition’s Patent Portfolio Grows to Europe and Canada Stratum Nutrition’s Patent Portfolio Grows to Europe and Canada
    Beyond Raw Launches Concept X Pre-Workout Line Beyond Raw Launches Concept X Pre-Workout Line
    Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission
    Experts Debate Role of Supplements in Improving Public Health in EU Experts Debate Role of Supplements in Improving Public Health in EU
    Tocotrienols May Aid Weight Loss and Cognitive Performance, Animal Study Finds Tocotrienols May Aid Weight Loss and Cognitive Performance, Animal Study Finds
    Tocotrienols May Aid Weight Loss and Cognitive Performance, Animal Study Finds Tocotrienols May Aid Weight Loss and Cognitive Performance, Animal Study Finds
    Indena Spotlights ‘Fabulous Four’ Ingredients Indena Spotlights ‘Fabulous Four’ Ingredients
    Vitamin D3, Omega-3s, Exercise May Cumulatively Reduce Cancer Risk in Older Adults Vitamin D3, Omega-3s, Exercise May Cumulatively Reduce Cancer Risk in Older Adults
    Vitamin Angels’ Mother’s Day Donation Campaign Raises Awareness for Maternal and Child Nutrition Vitamin Angels’ Mother’s Day Donation Campaign Raises Awareness for Maternal and Child Nutrition
     Solabia Algitech will Showcase Its Algae-Based Ingredients Solabia Algitech will Showcase Its Algae-Based Ingredients
    IFF to Discuss Customizable, Sustainable Solutions for Supplements IFF to Discuss Customizable, Sustainable Solutions for Supplements
    What to Expect Next Week at Vitafoods Europe 2022 What to Expect Next Week at Vitafoods Europe 2022
    Nutraceuticals for Men: Muscle Health and Performance Nutrition Nutraceuticals for Men: Muscle Health and Performance Nutrition
    Aging in Place: Healthy Lifestyles Supplement Science-Based Solutions Aging in Place: Healthy Lifestyles Supplement Science-Based Solutions
    OmegaQuant Launches HbA1c Test OmegaQuant Launches HbA1c Test

    Related Content

    • Breaking News | Regulations | Supplier News | World Markets
      Stratum Nutrition’s Patent Portfolio Grows to Europe and Canada

      Stratum Nutrition’s Patent Portfolio Grows to Europe and Canada

      CTX-II clinical model patent has been used in multiple clinical trials to show NEM eggshell membrane helps protect cartilage in exercising individuals.
      05.24.22

    • Breaking News | Dietary Supplements | Energy | Products | Sports Nutrition
      Beyond Raw Launches Concept X Pre-Workout Line

      Beyond Raw Launches Concept X Pre-Workout Line

      The 16-ingredient formulation targets both muscle soreness and increased strength acceleration.
      05.23.22

    • Breaking News | Diabetes & Blood Sugar Management | Industry & Market News | Medical Nutrition
      Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission

      Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission

      The American College of Lifestyle Medicine, with multi-organizational support, said that plant-predominant diets can achieve remission ahead of other treatment.
      05.19.22


    • Dietary Supplements | Healthy Aging | Regulations | World Markets
      Experts Debate Role of Supplements in Improving Public Health in EU

      Experts Debate Role of Supplements in Improving Public Health in EU

      At a panel discussion supported by Food Supplements Europe, stakeholders discussed regulation, bridging nutrient gaps, nutrition literacy, and more.
      By Mike Montemarano, Associate Editor 05.16.22

    • Tocotrienols May Aid Weight Loss and Cognitive Performance, Animal Study Finds

      Tocotrienols May Aid Weight Loss and Cognitive Performance, Animal Study Finds

      Full-spectrum palm tocotrienols inhibited weight gain and surpassed the blood brain barrier in supplemented mice.

      Trending
      • Leaven Essential To Launch Branded Botanical Extracts To Global Markets | Nutraceuticals World
      • Oregon Files Lawsuit Against GNC | Nutraceuticals World
      • Vitamin D3, Omega-3s, Exercise May Cumulatively Reduce Cancer Risk In Older Adults | Nutraceuticals World
      • Coca-Cola To Phase Out Honest Tea Brand By Year’s End, Citing Supply Chain Challenges | Nutraceuticals World
      Breaking News
      • Thorne Relaunches Gut Health Test with Microbiome Wipe
      • Alkemist Labs Announces Alkemist Assured Seal and Next Generation Transparency Reports
      • GC Rieber Foundations Expand Philanthropic Efforts
      • Danone Celebrates 10th anniversary of Grant Program for Probiotics Research
      • Stratum Nutrition’s Patent Portfolio Grows to Europe and Canada
      View Breaking News >
      CURRENT ISSUE

      May 2022

      • Aging in Place: Lifestyle Supplements Science-Based Solutions
      • Getting an Edge in Esports: Meeting Health & Nutrition Needs
      • Nutraceuticals for Men: Muscle Health and Performance Nutrition

      Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
      You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

      • About Us
      • Privacy Policy
      • Terms And Conditions
      • Contact Us

      follow us

      Subscribe
      Nutraceuticals World

      Latest Breaking News From Nutraceuticals World

      Thorne Relaunches Gut Health Test with Microbiome Wipe
      Alkemist Labs Announces Alkemist Assured Seal and Next Generation Transparency Reports
      GC Rieber Foundations Expand Philanthropic Efforts
      Coatings World

      Latest Breaking News From Coatings World

      ICP Receives ASC Innovation Award for Spray Foam That Meets Changing Environmental Regulations
      Pylon Coatings Uses Polygiene Biomaster & Verimaster for Antimicrobial Surface Protection
      Sto Corp. Recognized with Multiple Honors at the EIFS Hero Awards
      Medical Product Outsourcing

      Latest Breaking News From Medical Product Outsourcing

      Medtronic, DaVita to Create New Kidney Care Firm
      OmniGuide's RevoLix HTL Hybrid Thulium Laser OK'ed for BPH and Stone Treatments
      In Vitro Diagnostic Medical Devices Regulation Takes Effect
      Contract Pharma

      Latest Breaking News From Contract Pharma

      DFE Pharma Opens India CoE for Fast-Track Formulation Services
      Helsinn Establishes New R&D Hub in the U.S.
      CureVac, myNEO Partner on Antigen Targets for mRNA-Cancer Vax Development
      Beauty Packaging

      Latest Breaking News From Beauty Packaging

      Carlyle To Acquire HCP Packaging
      Estée Lauder Companies Faces Class Action Lawsuit
      La Roche-Posay Launches Matte Moisturizer for Oily Skin
      Happi

      Latest Breaking News From Happi

      Spate Announces Launch of French Data, New Color Complexion Trends Report
      Gojo Creates New All-Weather Purell Dispenser Built for Outdoor High Traffic Locations
      Women in Flavor and Fragrance Present 2022 Recognition Awards Dinner June 16
      Ink World

      Latest Breaking News From Ink World

      NAPIM’s Virtual Digital & Emerging Technologies Conference is Back, June 14–15, 2022
      CEMATEX Introduces Online Business Platform to Connect Global Textile Community
      PICO Chemical Celebrates 46 Years
      Label & Narrow Web

      Latest Breaking News From Label & Narrow Web

      Teklynx software helps Top Clean Injection validate labels
      Zeller+Gmelin named Berry Global’s 2021 Ink Supplier of the Year
      Videojet and Loftware partner to accelerate labeling automation
      Nonwovens Industry

      Latest Breaking News From Nonwovens Industry

      Rael Raises $35M in Series B Funding
      Schobertechnologies Offers Rotary Web-fed Converting Solutions
      Thorne Relaunches Gut Health Test with Microbiome Wipe
      Orthopedic Design & Technology

      Latest Breaking News From Orthopedic Design & Technology

      ManaMed's ManaSport Wearable Ultrasound Earns FDA Nod
      Ekso Bionics Names Jerome Wong as Interim CFO
      Exactech Completes First Surgeries Using Next-Gen Cage Glenoid
      Printed Electronics Now

      Latest Breaking News From Printed Electronics Now

      ams OSRAM Introduces New Horticulture LEDs
      Avery Dennison Launches AD Twist U7XM Inlays
      ARPA-E Funding Drives Innovation, Industry Partnerships at NREL

      Copyright © 2022 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

      AD BLOCKER DETECTED

      Our website is made possible by displaying online advertisements to our visitors.
      Please consider supporting us by disabling your ad blocker.


      FREE SUBSCRIPTION Already a subscriber? Login