• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    ‘Identifying the Elephant in the Room’: Confronting Controversial Topics

    Products Featuring Sustainability Claims Gain Greater Share of Consumer Spending

    PowerBar Maker Jennifer Maxwell Drums Up Organic Energy with JamBar Brand

    Economic Pressures Lead to Slower Growth in Dietary Supplement Industry

    Supporting Musculoskeletal Health: Tending to Muscles, Joints, and Bones
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Glossary
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    ABC Sustainable Herbs Program Releases Video on Regenerative Herb Farming in Costa Rica

    Activ’Inside Receives U.S. Patent for Saffron Extract

    Jiaherb Receives CITES Certification for Rhodiola Rosea

    Hyaluronic Acid Ingredient Linked to Antioxidant Benefits In Vitro

    Anita Johansen Appointed New CEO of Probi
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    ABC Sustainable Herbs Program Releases Video on Regenerative Herb Farming in Costa Rica

    Activ’Inside Receives U.S. Patent for Saffron Extract

    Jiaherb Receives CITES Certification for Rhodiola Rosea

    Anita Johansen Appointed New CEO of Probi

    Wiley Eliminates Outer Carton From Packaging to Reduce Waste
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    Activ’Inside Receives U.S. Patent for Saffron Extract

    Jiaherb Receives CITES Certification for Rhodiola Rosea

    Hyaluronic Acid Ingredient Linked to Antioxidant Benefits In Vitro

    Anita Johansen Appointed New CEO of Probi

    ‘Identifying the Elephant in the Room’: Confronting Controversial Topics
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    Activ’Inside Receives U.S. Patent for Saffron Extract

    Hyaluronic Acid Ingredient Linked to Antioxidant Benefits In Vitro

    Kemin Human Nutrition & Health Acquires Oral Health Ingredient

    Economic Pressures Lead to Slower Growth in Dietary Supplement Industry

    NPA: ‘Major Victory’ in Colorado After Amendment to Eating Disorder Bill
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    Nutrition21, LLC

    Botanic Healthcare LLC

    JRS Pharma

    BGG Americas, Inc.

    PhytoGaia Inc
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    Nutrition21, LLC

    Botanic Healthcare LLC

    JRS Pharma

    BGG Americas, Inc.

    PhytoGaia Inc
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Breaking News

    Deficiencies in Vitamins D and K Independently Linked to COVID-19 Severity

    A new study supported by Kappa Bioscience showed that these two vitamins could play independent roles in the disease’s pathogenesis.

    Deficiencies in Vitamins D and K Independently Linked to COVID-19 Severity
    10.25.21
    Concentrations of both vitamins D and K could play a role in the severity of COVID-19 infections, according to a new independent study supported by Kappa Bioscience, expounding upon previous publications which have observed links between these deficiencies and severe COVID-19. While the trial was preliminary in nature and observational, the results warranted further research investigating preventive measures in larger population sizes, the authors said.
     
    The present study, published in Open Forum Infectious Diseases, examined the influence of both of these vitamins independently on the course of COVID-19 in 100 COVID-19 patients, compared to a control group of 50 people, measuring their vitamin D and vitamin K levels.
     
    Compared to the healthy control group, the authors of the study noted that levels of DP-ucMGP, a biomarker for vitamin K status, was significantly lower in the COVID-19 group.
     
    While across the COVID-19 and control groups, vitamin D levels were not significantly different, vitamin D deficiency experienced the most severe COVID-19 outcomes. Approximately 15% of the COVID-19 group was classified as having a severe case. Vitamin K deficiencies were also strongly associated with vitamin D deficiency.
     
    Specifically, every one-unit increase in DP-ucMGP levels (stronger vitamin K deficiency) nearly doubled the odds of acute critical disease or death, and every one-unit decrease in blood concentrations of vitamin D was associated with greater than three-times the likelihood of severe COVID-19 disease.
     
    The two vitamins have been previously-established to exhibit synergistic benefits to bone and cardiovascular health, but as this is an observational study, no mechanisms of action could be established for the independent, protective benefits that vitamins K and D had in the COVID-19 patients studied. However, the authors of the study proposed that it may have to do with previously-established benefits to calcium metabolism dependent on adequate intakes on both vitamins.
     
    “Put simply, vitamin D enables the production of some key proteins, which paly a role in calcium metabolism. But they are produced in an inactive state, and vitamin K2 is the catalyst that activates them,” Trygve Bergeland, vice president of science at Kappa Bioscience, said. “These proteins mobilize calcium, carrying it away from our arteries and soft tissues, and incorporating it into our bones, where it is needed. In COVID-19, it was shown that patients with low vitamin K status had increased elastic fiber degradation and vascular calcifications. On its own, vitamin K also regulates blood clotting, which seems crucial to prevent thromboembolism, as often observed in more severe COVID-19.”
     
    “Interestingly, both vitamin D and K may display complementary effects on the cytokine storm, thrombosis, and lung damage during COVID-19. Specifically, they display similar inhibitory effects on inhibition of NF-kB and cytokine release, and vitamins D and K appear to work synergistically to help protect against calcification and damage in the lungs,” said Dr. Grace McComsey, MD, FIDSA, vice president of research and associate chief scientific officer at University Hospitals. McComsey is a corresponding author of the study.
     
    “Optimizing vitamins K and D prior to acute COVID-19 infection may help to regulate overwhelming calcification, inflammation, and coagulopathy, which may subsequently lead to improved clinical outcomes,” McComsey continued. “As the long-chain menaquinones, such as K2 MK-7 [a specific form of vitamin K] have an extrahepatic distribution, they possess the capacity to optimize the vitamin K status in tissues that are deficient, however, large preventive clinical trials are needed.”
     
     
    Related Searches
    • Contract Manufacturing
    • Cardiovascular Health
    • Antioxidants
    • Research
    Related Knowledge Center
    • Dietary Supplements
    • Immune Function
    • Research
    • Cardiovascular Health
    • Medical Nutrition
    • Contract Manufacturing
    • Bone & Joint Health
    • Antioxidants
    • Vitamins
    Suggested For You
    ‘Identifying the Elephant in the Room’: Confronting Controversial Topics ‘Identifying the Elephant in the Room’: Confronting Controversial Topics
    Economic Pressures Lead to Slower Growth in Dietary Supplement Industry Economic Pressures Lead to Slower Growth in Dietary Supplement Industry
    Harmonizing the EU Harmonizing the EU's Upper Limits For Micronutrients
    Podcast: Erin Stokes, ND, on Natural Health Strategies and the Role for Dietary Supplements Podcast: Erin Stokes, ND, on Natural Health Strategies and the Role for Dietary Supplements
    'What’s Up With Supps' Event at Expo West Raises Over $8,000 for Vitamin Angels
    Disappearing Act: The Battle Over Dietary Supplement Ingredients and the Drug Exclusion Provision Disappearing Act: The Battle Over Dietary Supplement Ingredients and the Drug Exclusion Provision
    Vitamin D Remains Top Supplement Among Users, Popularity of Probiotics on the Rise: ConsumerLab Vitamin D Remains Top Supplement Among Users, Popularity of Probiotics on the Rise: ConsumerLab
    Hologram Sciences Partners with Haleon in United States Hologram Sciences Partners with Haleon in United States
    Supporting Musculoskeletal Health: Tending to Muscles, Joints, and Bones Supporting Musculoskeletal Health: Tending to Muscles, Joints, and Bones
    Dosage and Delivery Innovations Help Manufacturers Meet Common Challenges Dosage and Delivery Innovations Help Manufacturers Meet Common Challenges
    High Omega-3 Index Linked to Reduced Rate of Severe COVID-19 Infection High Omega-3 Index Linked to Reduced Rate of Severe COVID-19 Infection
    A Paradigm Shift for Antioxidants? A Paradigm Shift for Antioxidants?
    Can a Triple Action Dream Team Solve Your ‘Everyday Energy Crisis?’ Can a Triple Action Dream Team Solve Your ‘Everyday Energy Crisis?’
    HMB and Vitamin D Supplementation Linked to Reduction in Fat Stores HMB and Vitamin D Supplementation Linked to Reduction in Fat Stores
    Ayana Bio on Path to Scale Bioactives Derived from Plant Cell Cultures Ayana Bio on Path to Scale Bioactives Derived from Plant Cell Cultures

    Related Features

    • Consumer Trends | Dietary Supplements | Natural/Organic
      ‘Identifying the Elephant in the Room’: Confronting Controversial Topics

      ‘Identifying the Elephant in the Room’: Confronting Controversial Topics

      It’s our responsibility to press on difficult issues like sexism and racism in order to improve experiences for the next generation.
      By Sean Moloughney, Editor 03.30.23

    • Cognitive Function | Consumer Trends | Dietary Supplements | Mood Health & Sleep | Sports Nutrition | Weight Management/Weight Loss
      Economic Pressures Lead to Slower Growth in Dietary Supplement Industry

      Economic Pressures Lead to Slower Growth in Dietary Supplement Industry

      Sports nutrition, mood/stress/mental health, sleep, and weight management are leading growth segments, sales data indicates.
      By Mike Montemarano, Associate Editor 03.27.23

    • Minerals | Quality & Safety | Regulations | Vitamins | World Markets
      Harmonizing the EU

      Harmonizing the EU's Upper Limits For Micronutrients

      EFSA’s recent draft opinion proposes significantly lowering the upper intake level for vitamin B6, drawing industry criticism and concern.
      By Joerg Gruenwald, analyze & realize GmbH 03.24.23


    • Digestive Health | Herbs & Botanicals | Natural/Organic | Women's Health
      Podcast: Erin Stokes, ND, on Natural Health Strategies and the Role for Dietary Supplements

      Podcast: Erin Stokes, ND, on Natural Health Strategies and the Role for Dietary Supplements

      MegaFood’s medical director addresses nutrient density and soil health, mood and the microbiome, and underserved women’s health issues.
      Sean Moloughney, Editor 03.21.23

    • Breaking News | Dietary Supplements | Industry & Market News | Infant & Children's Health | Women's Health

      'What’s Up With Supps' Event at Expo West Raises Over $8,000 for Vitamin Angels

      Donation will contribute to nonprofit’s mission to improve nutrition and health outcomes for pregnant women, infants, and young children worldwide.
      03.17.23

    Loading, Please Wait..
    Trending
    • ConsumerLab Finds High Concentrations Of Arsenic In Cricket Protein Powder
    • Shiitake Mushroom Extract Appears Helpful In HPV Infections
    • HMB And Vitamin D Supplementation Linked To Reduction In Fat Stores
    • ACG Expands As Vantage Nutrition Acquires ComboCap And Its Dual-Chamber Capsule Technology
    • Jiaherb Receives CITES Certification For Rhodiola Rosea
    Breaking News
    • ABC Sustainable Herbs Program Releases Video on Regenerative Herb Farming in Costa Rica
    • Activ’Inside Receives U.S. Patent for Saffron Extract
    • Jiaherb Receives CITES Certification for Rhodiola Rosea
    • Hyaluronic Acid Ingredient Linked to Antioxidant Benefits In Vitro
    • Anita Johansen Appointed New CEO of Probi
    View Breaking News >
    CURRENT ISSUE

    March 2023

    • Supporting Musculoskeletal Health: Tending to Muscles, Joints, and Bones
    • Dosage and Delivery Innovations Help Manufacturers Meet Common Challenges
    • 2023 Contract Manufacturing Survey
    • Manufacturing Dietary Supplements in Economic Uncertainty
    • Beyond Antioxidants: The Power of Berries
    • A Paradigm Shift for Antioxidants?
    • Ayana Bio on Path to Scale Bioactives Derived from Plant Cell Cultures
    • Nuritas: Leveraging Artificial Intelligence to Speak the Language of Life
    • Dietary Supplement Quality Assurance Programs Critical to Natural Products Industry Success
    • Innovation in Nutraceuticals: Dose Forms and Application Science Help Meet Consumer Demand
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    ABC Sustainable Herbs Program Releases Video on Regenerative Herb Farming in Costa Rica
    Activ’Inside Receives U.S. Patent for Saffron Extract
    Jiaherb Receives CITES Certification for Rhodiola Rosea
    Coatings World

    Latest Breaking News From Coatings World

    BASF’s Monomers Division Receive ISCC+ Certification in Its Two Asian Production Sites
    Omya to Represent Songwon’s Coatings Portfolio in 4 South-Asian Countries
    Brenntag Commences Operations at Its New Site in Zhangjiagang, China
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    MPO's Most-Read Stories This Week—April 1
    SoCalBio Mourns the Loss of CEO Ahmed Enany
    Tissium's COAPTIUM Connect Achieves Successful Nerve Repair in Australia
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Duke-Margolis Launches Drug Supply Chain Resilience, Advanced Manufacturing Consortium
    Galapagos, NovAliX Enter Integrated Drug Discovery Collaboration
    XOMA Acquires IXINITY Asset from Aptevo Therapeutics
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Venus Launches Dermaplaning Skincare Regimen
    Olberding Brand Family Updates Leadership Team and Expands Capabilities
    Rimmel London Chooses Maya Jama as the New Face of the Brand
    Happi

    Latest Breaking News From Happi

    Fenty Beauty Illuminates NYC Skyline to Introduce Hella Thicc Volumizing Mascara
    Huda Beauty Launches GloWish Bright Light Sheer Concealer
    Digging Into Dollar General's Beauty Expansion Plans
    Ink World

    Latest Breaking News From Ink World

    Ricoh Wins 2023 ENERGY STAR Partner of the Year Sustained Excellence Award from EPA
    Avery Dennison Implements Carbon Trust Footprinting Tool
    ACTEGA to Showcase Products and Solutions at Interpack 2023
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    PCMC names Windell McGill product launch manager
    Nominations sought for The Paper and Packaging Board's 2024 board seats
    CUPSZ chooses Mark Andy Evolution Series E5
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Windell McGill Joins PCMC
    Binder Unveils New Look, Website
    Michelman Achieves EcoVadis Rting
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    ODT's Most-Read Stories This Week—April 1
    European Innovation Council Awards Grant for Brain-Computer Interface Tech
    Report: No Complications With OssDsign Catalyst Graft
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    India Awards Production Linked Incentives to First Solar’s India Facility
    onsemi Named to Barron’s 2023 List of 100 Most Sustainable Companies in the U.S.
    Michelman Earns 2023 EcoVadis Gold Sustainability Rating

    Copyright © 2023 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login