06.01.10
Nutraceutical: DHA
Indication: Cognitive function
Source: Alzheimers Dement, April 29, 2010 [Epub ahead of print]
Research: MIDAS is the first large, randomized, placebo-controlled study demonstrating the effects of algal DHA in maintaining and improving brain health in older adults. The goal of MIDAS was to evaluate the effects of algal DHA on cognitive outcomes in healthy elderly people with a mild memory complaint. The study population included 485 people age 55 and older at 19 U.S. sites who were considered to have age-related cognitive decline. Age-related cognitive decline is defined as decline in cognitive functioning consequent to the aging process that is within normal limits given a person’s age. For example, individuals may report problems remembering names or appointments or may experience difficulty solving complex problems. MIDAS study participants consumed an oral dose of 900 mg per day of algal DHA or a placebo (corn/soy) over the course of six months. The primary endpoint was a cognitive test of memory and learning.
Results: The study found that healthy people with memory complaints who took 900 mg algal DHA capsules for six months had almost double the reduction in errors on a test that measures learning and memory performance versus those who took a placebo, a benefit roughly equivalent to having the learning and memory skills of someone three years younger. The DHA was well-tolerated. In fact, subjects taking the DHA also experienced a lower heart rate, providing a significant cardiovascular benefit.