• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    Nutraceuticals for Men: Muscle Health and Performance Nutrition

    Aging in Place: Healthy Lifestyles Supplement Science-Based Solutions

    Getting an Edge in Esports: Meeting the Health Needs of Competitive Gamers

    Beyond CBD: Cannabis Compounds Warrant Recognition and More Research

    Leveling Out the Energy Segment for Mainstream, and Rethinking Caffeine
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    Nootropics and Adaptogens Respond to Demand for Mind and Mood Support

    Sabinsa Honors 70th Anniversary of Diplomacy Between India and Japan

    Solvay Invests in Suanfarma’s Vanillin Production

    GNC Adds Products from The Honest Company, Hers, and Womaness

    NSF and SCNM’s School of Nutrition Collaborate on Master of Science Program
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    Nootropics and Adaptogens Respond to Demand for Mind and Mood Support

    Sabinsa Honors 70th Anniversary of Diplomacy Between India and Japan

    Solvay Invests in Suanfarma’s Vanillin Production

    Tocotrienols May Aid Weight Loss and Cognitive Performance, Animal Study Finds

    Leaven Essential to Launch Branded Botanical Extracts to Global Markets
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    Nootropics and Adaptogens Respond to Demand for Mind and Mood Support

    Sabinsa Honors 70th Anniversary of Diplomacy Between India and Japan

    Experts Debate Role of Supplements in Improving Public Health in EU

    Solvay Invests in Suanfarma’s Vanillin Production

    GNC Adds Products from The Honest Company, Hers, and Womaness
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    Nootropics and Adaptogens Respond to Demand for Mind and Mood Support

    Experts Debate Role of Supplements in Improving Public Health in EU

    GNC Adds Products from The Honest Company, Hers, and Womaness

    Tocotrienols May Aid Weight Loss and Cognitive Performance, Animal Study Finds

    Red Seaweed Digestive Supplement for Cattle Could Reduce Enteric Methane Emissions by 80%
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    Nutrition21, LLC

    ESHA Research

    Sabinsa Corporation

    KLK OLEO

    Atlantia Clinical Trials
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    Nutrition21, LLC

    ESHA Research

    Sabinsa Corporation

    KLK OLEO

    Atlantia Clinical Trials
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Breaking News

    Large Meta-Analysis Backs Benefits of Probiotic for Gut Health

    Analysis of clinical trials shows efficacy of Medilac-S as adjuvant treatment in ulcerative colitis and prevention of anti-inflammatory side effects.

    Large Meta-Analysis Backs Benefits of Probiotic for Gut Health
    Related CONTENT
    • Manufacturing Equipment Technology & Trends
    • Oral Solids Endure & Evolve
    • Health-Conscious Gen Z Adults Want Convenient Foods that Match Busy Lifestyles
    • ABC Updates Monograph on Scientific and Clinical Research on Pycnogenol
    • High Intake of Dietary Fiber & Whole Grains May Reduce Risk of Non-Communicable Diseases
    01.11.19
    A systematic review and meta-analysis was recently published in the World Journal of Clinical Cases that asses the effects of probiotic preparation Medilac-S (Enterococcus faecium Rosell-26 and Bacillus subtilis Rosell-179), as adjunctive therapy in ulcerative colitis patients. Involving 53 randomized clinical trials and close to 4,000 patients altogether, this robust meta-analysis concluded that, when used with conventional drugs, this probiotic significantly improved chances of clinical remission by 21%, improved symptoms of the gastrointestinal tract, and reduced the risk of side-effects from anti-inflammatory drugs, as compared to the drug alone.  
     
    Dr. Thomas Tompkins, research director for Lallemand Health Solutions and co-author of the study explained, “Until now, reviews conducted on the efficacy of probiotics as ulcerative colitis adjunctive therapy were difficult to interpret due to the lack of homogeneity in the trials analyzed. The present study is quite robust and consistent since it involves the largest number of randomized control trials (53), homogenous in terms of trial design, disease state, probiotic formulation used, and population. We closely analyzed risk of bias for all studies. It is probably the strongest meta-analysis conducted so far with a single probiotic formulation.”  He added, “Not only the analysis showed significant outcome in terms of gut health support, but also a reduction of the incidence of the side effects induced by anti-inflammatory drugs, suggesting a role for this probiotic in the prevention of 5-ASA side effects.”
     
    Solange Henoud, regulatory affairs director for Lallemand Health Solutions, added, “Medilac-S has continuous records of sale as a drug in China for over than 30 years, where it is well-known and trusted by consumers and healthcare professionals. In other instances, the safety and quality of the strains have been successfully demonstrated or notified with non-objection to other competent authorities in the three continents of America, Europe, and Asia.”
     
    Ulcerative colitis is an inflammatory bowel disease of the colonic gastrointestinal tract that is steadily increasing across the globe. Conventional treatments include anti-inflammatory drugs. In China, where the disease is growing rapidly, probiotics, and in particular Medilac-S formula has been used as adjuvant therapy for many years. The 53 clinical trials included in the meta-analysis span from 2007 to 2017. 
     
    Potential mechanisms of action of the probiotic formula to explain the adjuvant effect include improvement of the gut microbiota balance, immune-modulatory effects, protection against undesired microorganisms that may trigger a recurrence, also, as recently suggested, a role of certain probiotics in drug pharmacokinetics.
    Related Searches
    • China
    • Gut Health
    • Prevention
    • Regulatory
    Related Knowledge Center
    • Probiotics & Prebiotics
    • Research
    • Digestive Health
    Suggested For You
    Oral Solids Endure & Evolve Oral Solids Endure & Evolve
    Manufacturing Equipment Technology & Trends Manufacturing Equipment Technology & Trends
    Health-Conscious Gen Z Adults Want Convenient Foods that Match Busy Lifestyles Health-Conscious Gen Z Adults Want Convenient Foods that Match Busy Lifestyles
    ABC Updates Monograph on Scientific and Clinical Research on Pycnogenol ABC Updates Monograph on Scientific and Clinical Research on Pycnogenol
    High Intake of Dietary Fiber & Whole Grains May Reduce Risk of Non-Communicable Diseases High Intake of Dietary Fiber & Whole Grains May Reduce Risk of Non-Communicable Diseases
    NOW Launches BioCell Collagen Dietary Supplement NOW Launches BioCell Collagen Dietary Supplement
    Aging Cats & Dogs Drive Market for Functional Pet Foods Aging Cats & Dogs Drive Market for Functional Pet Foods
    Study Reveals Fucoidan Extract Reduces Gut Inflammation Study Reveals Fucoidan Extract Reduces Gut Inflammation
    Demystifying the Regulatory Status of CBD Demystifying the Regulatory Status of CBD
    Riding the Sports Nutrition Wave: Energy, Endurance & Recovery Riding the Sports Nutrition Wave: Energy, Endurance & Recovery
    Immune Health: Building a Foundation of Wellness Immune Health: Building a Foundation of Wellness
    Active Ingredients for Mood & Sleep, A-Z Active Ingredients for Mood & Sleep, A-Z
    Is Google’s AdSense System Biased Against Dietary Supplements? Is Google’s AdSense System Biased Against Dietary Supplements?
    Court Orders Injunction Against Companies Selling Products with Undisclosed Drugs Court Orders Injunction Against Companies Selling Products with Undisclosed Drugs

    Related Content

    • Contract Manufacturing | Packaging | Quality & Safety | Testing
      Manufacturing Equipment Technology & Trends

      Manufacturing Equipment Technology & Trends

      Potent drug products, delivery systems, continuous manufacturing, and digitization drive innovation.
      By Kristin Brooks, Managing Editor, Contract Pharma 03.01.19

    • Contract Manufacturing | Delivery & Dosage Technologies | World Markets
      Oral Solids Endure & Evolve

      Oral Solids Endure & Evolve

      Contract service providers discuss the state of the oral solid dose development and manufacturing market.
      By Tim Wright, Editor, Contract Pharma 03.01.19

    • Breaking News | Consumer Trends | Industry & Market News | Natural/Organic | Nutrition Bars & Snacks
      Health-Conscious Gen Z Adults Want Convenient Foods that Match Busy Lifestyles

      Health-Conscious Gen Z Adults Want Convenient Foods that Match Busy Lifestyles

      Compared to their millennial counterparts a decade ago, 18 to 24-year-olds today are more likely to look for organic or natural foods.
      02.14.19


    • Breaking News | Herbs & Botanicals | Research | Research News
      ABC Updates Monograph on Scientific and Clinical Research on Pycnogenol

      ABC Updates Monograph on Scientific and Clinical Research on Pycnogenol

      Document describes scientific data supporting various uses of the French maritime pine bark extract.
      02.08.19

    • Cancer Risk | Cardiovascular Health | Diabetes & Blood Sugar Management | Fiber & Carbohydrates | Research | Weight Management/Weight Loss
      High Intake of Dietary Fiber & Whole Grains May Reduce Risk of Non-Communicable Diseases

      High Intake of Dietary Fiber & Whole Grains May Reduce Risk of Non-Communicable Diseases

      Review offers compelling evidence that quality carbohydrates are major determinants of numerous health outcomes.
      01.28.19

      Breaking News
      • Nootropics and Adaptogens Respond to Demand for Mind and Mood Support
      • Sabinsa Honors 70th Anniversary of Diplomacy Between India and Japan
      • Solvay Invests in Suanfarma’s Vanillin Production
      • GNC Adds Products from The Honest Company, Hers, and Womaness
      • NSF and SCNM’s School of Nutrition Collaborate on Master of Science Program
      View Breaking News >
      CURRENT ISSUE

      May 2022

      • Aging in Place: Lifestyle Supplements Science-Based Solutions
      • Getting an Edge in Esports: Meeting Health & Nutrition Needs
      • Nutraceuticals for Men: Muscle Health and Performance Nutrition

      Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
      You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

      • About Us
      • Privacy Policy
      • Terms And Conditions
      • Contact Us

      follow us

      Subscribe
      Nutraceuticals World

      Latest Breaking News From Nutraceuticals World

      Nootropics and Adaptogens Respond to Demand for Mind and Mood Support
      Sabinsa Honors 70th Anniversary of Diplomacy Between India and Japan
      Solvay Invests in Suanfarma’s Vanillin Production
      Coatings World

      Latest Breaking News From Coatings World

      DIC’s Indian Subsidiary Begins Construction of Coating Resins Production Facility
      Celanese Declares Force Majeure on Acetyl Chain and Acetate Tow Products
      CPI Announces New Hybrid Professional Development Program for 2022
      Medical Product Outsourcing

      Latest Breaking News From Medical Product Outsourcing

      Linear Health Sciences’ Orchid SRV Receives FDA & Health Canada Approval
      Vivasure Medical Raises $23 Million in Series D Financing Round
      New Patents Add Value to Know Labs' Bio-RFID Tech
      Contract Pharma

      Latest Breaking News From Contract Pharma

      Evotec SE and Sernova Corp Announce Partnership in the Field of Diabetes
      Emergex COVID-19 Vaccine Candidate Successfully Coated onto Zosano Micro-Needle Patch
      Thabor Therapeutics Appoints Jérémie Mariau as CEO
      Beauty Packaging

      Latest Breaking News From Beauty Packaging

      Aveda is Leaping Bunny Approved by Cruelty Free International
      Smashbox Expands Becca Highlighter Collection
      Bite Beauty Is Closing Later This Year
      Happi

      Latest Breaking News From Happi

      Filipino Cosmetics Company Sunnies Face Enters US Market
      Selig Group Names Adam Sheridan Next President
      Nautica Introduces Oceans Pacific Coast Vegan & Sustainable Fine Fragrance Collection
      Ink World

      Latest Breaking News From Ink World

      Nazdar Ink Technologies to Manufacture VFP Ink Technologies Electronic Inks for US
      Sun Chemical Heads to Flexo and Labels 2022
      PETRONAS Chemicals Group to Acquire Perstorp Group
      Label & Narrow Web

      Latest Breaking News From Label & Narrow Web

      Essentra Packaging invests in Landa Nanographic press
      Nazdar to manufacture VFP electronic ink for US Market
      SunDance moves into flexible packaging with HP Indigo
      Nonwovens Industry

      Latest Breaking News From Nonwovens Industry

      H&V Appoints Vice President and General Counsel
      The Honest Company to Sell Diapers, Wipes at Walmart
      Jim Cree Joins Monadnock Nonwovens
      Orthopedic Design & Technology

      Latest Breaking News From Orthopedic Design & Technology

      Paragon 28 Launches Grappler Suture Anchor System
      Paul Stellato Appointed Chief Accounting Officer at Zimmer Biomet
      DuPuy Synthes’ INHANCE Shoulder System Cleared by FDA for Reverse Total Shoulder Arthroplasty
      Printed Electronics Now

      Latest Breaking News From Printed Electronics Now

      Jabil Strengthens Additive Manufacturing Offerings
      Avery Dennison, Wiliot Partner to Build and Scale the Future of IoT
      HP Delivers Enhanced Platform Capabilities to Accelerate Additive Manufacturing Production at Scale

      Copyright © 2022 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

      AD BLOCKER DETECTED

      Our website is made possible by displaying online advertisements to our visitors.
      Please consider supporting us by disabling your ad blocker.


      FREE SUBSCRIPTION Already a subscriber? Login