04.01.08
Indication: Inflammation
Source: Am J Clin Nutr, February 2008;87(2):424-30.
Research: The purpose of this study was to investigate the associations between dietary choline and betaine consumption and various markers of low-grade systemic inflammation. This cross-sectional survey enrolled 3042 healthy men and women between the ages of 18 to 89 years taking part in the ATTICA Study. A validated food-frequency questionnaire (FFQ) was used to assess dietary intakes and blood samples were collected to measure levels of inflammatory markers.
Results: Researchers reported that participants with the highest intake of choline (over 310 mg daily) had at least 20% lower concentrations of inflammatory markers in comparison to participants with the lowest intake of choline (less than 250 mg daily). Similar results were obtained from betaine intake. The highest intake (over 360 mg daily) resulted in 19% lower concentrations of C-reactive protein, 10% lower homocysteine levels and 12% lower TNF-alpha levels in comparison to participants with the lowest intake of betaine (less than 260 mg daily). The authors concluded that higher consumption of choline and betaine was associated with decreased levels of homocysteine, which may reduce the risk of a number of diseases.
Source: Am J Clin Nutr, February 2008;87(2):424-30.
Research: The purpose of this study was to investigate the associations between dietary choline and betaine consumption and various markers of low-grade systemic inflammation. This cross-sectional survey enrolled 3042 healthy men and women between the ages of 18 to 89 years taking part in the ATTICA Study. A validated food-frequency questionnaire (FFQ) was used to assess dietary intakes and blood samples were collected to measure levels of inflammatory markers.
Results: Researchers reported that participants with the highest intake of choline (over 310 mg daily) had at least 20% lower concentrations of inflammatory markers in comparison to participants with the lowest intake of choline (less than 250 mg daily). Similar results were obtained from betaine intake. The highest intake (over 360 mg daily) resulted in 19% lower concentrations of C-reactive protein, 10% lower homocysteine levels and 12% lower TNF-alpha levels in comparison to participants with the lowest intake of betaine (less than 260 mg daily). The authors concluded that higher consumption of choline and betaine was associated with decreased levels of homocysteine, which may reduce the risk of a number of diseases.