The aim of this study was to evaluate the effect of Peptan on the bone health of ovariectomized mice (OVX) of different ages. Animals were divided into different groups: some groups of mice ingested Peptan after OVX; another group of mice ingested Peptan several weeks before OVX and continued over additional weeks; another ingested Raloxifene—a drug commonly indicated for osteoporosis—instead of hydrolyzed collagen.
Twenty-six weeks after the OVX procedure, Peptan hydrolyzed collagen ingestion improved Bone Mineral Density (BMD) and some femur biomechanical parameters. Moreover, hydrolyzed collagen ingestion for one month before surgery prevented a BMD decrease. The third major finding was that Peptan prevented a decrease in BMD as efficiently as Raloxifene. For further information: www.rousselot.com