• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    Contract Manufacturing: Trials & Tribulations of Today’s Supply Chains

    Analytical Testing in Nutraceuticals: Methods and Mindsets to Uphold Quality

    Nutrition and Flavor: Formulating for Modern Product Preferences

    What Do Consumers Know About the Gut Microbiome?

    How Will the European Green Deal Impact Dietary Supplements?
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    Flower Pollen Extract Benefits Women’s Urinary Incontinence, Study Finds

    3i Solutions Announces New Leadership Positions

    INS Nutra Opens Gummy Manufacturing Facility

    Vital Nutrients Launches First Vegan Omega Supplement with SPMs

    Earth Mama Organics Achieves 'Plastic Neutral' Certification
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    Flower Pollen Extract Benefits Women’s Urinary Incontinence, Study Finds

    Vital Nutrients Launches First Vegan Omega Supplement with SPMs

    Bill Chioffi Joins Nammex as Chief Strategy and Innovation Officer

    FDA Issues ‘No Questions’ Letter for Chiber Mushroom Fiber Preservative

    VITAL Ancillary Study Finds No Link Between Vitamin D and Bone Fracture Risk
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    Flower Pollen Extract Benefits Women’s Urinary Incontinence, Study Finds

    3i Solutions Announces New Leadership Positions

    INS Nutra Opens Gummy Manufacturing Facility

    Vital Nutrients Launches First Vegan Omega Supplement with SPMs

    Earth Mama Organics Achieves 'Plastic Neutral' Certification
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    Flower Pollen Extract Benefits Women’s Urinary Incontinence, Study Finds

    Vital Nutrients Launches First Vegan Omega Supplement with SPMs

    VITAL Ancillary Study Finds No Link Between Vitamin D and Bone Fracture Risk

    Krill Oil Study Provides Evidence of Osteoarthritis Benefits

    Immunobiotic Heat-Killed Bacteria Linked to Skin Benefits
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    Sabinsa Corporation

    Bioenergy Life Science, Inc. (BLS)

    KLK OLEO

    BGG World

    Ecuadorian Rainforest
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    Sabinsa Corporation

    Bioenergy Life Science, Inc. (BLS)

    KLK OLEO

    BGG World

    Ecuadorian Rainforest
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Breaking News

    Activity of Curcumin Supplements Highly Dependent on Formulation, Study Finds

    A recently-published study found that a novel dried colloidal suspension formulation had significantly stronger absorption rates.

    Activity of Curcumin Supplements Highly Dependent on Formulation, Study Finds
    Related CONTENT
    • Specnova Launches New Powder Form Delivery System
    • VITAL Ancillary Study Finds No Link Between Vitamin D and Bone Fracture Risk
    • Krill Oil Study Provides Evidence of Osteoarthritis Benefits
    • Immunobiotic Heat-Killed Bacteria Linked to Skin Benefits
    • Fish Oil Supplementation Effects Exercise Response in Older Women with Sarcopenia
    07.12.21
    The primary challenge formulators face when working with curcumin, an extract of turmeric root, is ensuring that the bioactive compounds are absorbed significantly upon ingestion. With this in mind, the industry has experimented with a number of pharmacokinetic innovations, a plethora of which are available commercially.
     
     A recent clinical trial found that a new dried colloidal suspension formulation used in the curcumin supplement ingredient Turmipure Gold, manufactured by Naturex, was shown to have the strongest bioavailability for both conjugated and unconjugated curcuminoids when compared to three other capsules and one liquid formulation, which included a standard turmeric powder extract, a phytosome formulation, and a piperine formulation, and the liquid formulation.
     
    However, in terms of total curcuminoid absorption levels, both Turmipure Gold and a liquid micellar formulation containing 6% curcuminoids (NovaSOL, manufactured by Aquanova AG) saw significantly higher bioavailability than the other formulations.
     
    The study enrolled 30 healthy men and women, and was a randomized, open-labeled, crossover trial. Each of the participants sequentially consumed single oral doses of each of the given formulations, which included various doses: a 1500 mg turmeric extract, a 1515 mg piperine-curcuminoid combination, a 1000 mg dose of phytosome formulation, and a 300 mg dose of the dried colloidal suspension formula.
     
    “Orally administered turmeric native compounds have a low intestinal absorption, and most are excreted unchanged,” the authors of the study said, adding that the bioactive compounds in curcumin are hydrophobic, and have low solubility in water. “Due to the combination of poor oral absorption, rapid metabolism, and rapid elimination from the systemic circulation, systemic concentrations of unconjugated curcumin do not exceed the low micromolar concentration in humans even after oral doses less than or equal to 12 grams.”
     
    The authors of the study noted that in addition to total curcuminoid levels, it was important to look at certain bioactive molecules rather than the entire content, due to multiple compounds within curcumin exerting unique properties which are linked to health benefits. These individual bioactive molecules include not just total curcumin, but also DMC and BDMC the latter two of which are unconjugated curcumin. In total, the researchers broke down blood concentrations of 15 curcuminoid metabolites in the study participants,  due in large part to the fact that it hasn’t been determined which of the curcumin compounds have the greatest scope of antioxidant activity in the human body.
     
    “To date, there is no consensus whether the activities of turmeric extract are due to unconjugated curcumin, DMC, or BDMC, or to their phase I and phase II metabolites,” the authors wrote, adding that evidence is especially mixed on BDMC across at least 22 trials to date.
     
    “In conclusion, enhanced bioavailability of turmeric curcuminoids is desirable in view of their encouraging various health benefits but challenged by their poor absorption and rapid metabolism […] Not all curcuminoid formulations were found to deliver equivalent pharmacokinetic profiles. Nevertheless, the new colloidal suspension TPG was revealed to be particularly promising in that 300 mg was sufficient to demonstrate bioequivalence to over 1500 mg of the standard turmeric extract.”
    Related Searches
    • Inflammation
    • Research
    • Herbs & Botanicals
    • World Markets
    Related Knowledge Center
    • Functional Foods & Beverages
    • Testing
    • Consumer Trends
    Suggested For You
    Specnova Launches New Powder Form Delivery System Specnova Launches New Powder Form Delivery System
    VITAL Ancillary Study Finds No Link Between Vitamin D and Bone Fracture Risk VITAL Ancillary Study Finds No Link Between Vitamin D and Bone Fracture Risk
    Krill Oil Study Provides Evidence of Osteoarthritis Benefits Krill Oil Study Provides Evidence of Osteoarthritis Benefits
    Immunobiotic Heat-Killed Bacteria Linked to Skin Benefits Immunobiotic Heat-Killed Bacteria Linked to Skin Benefits
     Fish Oil Supplementation Effects Exercise Response in Older Women with Sarcopenia Fish Oil Supplementation Effects Exercise Response in Older Women with Sarcopenia
    Boswellia Serrata Extract Shown in Study to Support Joint Function in Five Days Boswellia Serrata Extract Shown in Study to Support Joint Function in Five Days
    Curcuwin Ultra+ Linked to Positive Findings in Joint Health and Mobility Study Curcuwin Ultra+ Linked to Positive Findings in Joint Health and Mobility Study
    A Growing Herbal Products Market Still Faces Formidable Threats, Challenges A Growing Herbal Products Market Still Faces Formidable Threats, Challenges
    BC30 Probiotic Shown to Improve Absorption of Plant Protein BC30 Probiotic Shown to Improve Absorption of Plant Protein
    Medical Sales Representative Chiropractic – Irvine Medical Sales Representative Chiropractic – Irvine
    Medical Sales Representative – Denver Medical Sales Representative – Denver
    Medical Regional Sales Manager - Washington, DC Medical Regional Sales Manager - Washington, DC
    Medical Sales Representative – Atlanta Medical Sales Representative – Atlanta
    True Westfjords Launches Dropi Cod Liver Oil Tonic True Westfjords Launches Dropi Cod Liver Oil Tonic
    Younger Consumers Drive Growing Demand for Ingestible Beauty and Skin Care Products Younger Consumers Drive Growing Demand for Ingestible Beauty and Skin Care Products

    Related Breaking News

    • Breaking News | Delivery & Dosage Technologies | Dietary Supplements | Supplier News
      Specnova Launches New Powder Form Delivery System

      Specnova Launches New Powder Form Delivery System

      LipoVantage uses protective liposomes to maximize efficacy of active ingredients.
      08.03.22

    • Bone & Joint Health | Breaking News | Dietary Supplements | Research | Research News | Vitamins
      VITAL Ancillary Study Finds No Link Between Vitamin D and Bone Fracture Risk

      VITAL Ancillary Study Finds No Link Between Vitamin D and Bone Fracture Risk

      Andrea Wong, PhD, SVP of scientific and regulatory affairs for CRN, said with no control for calcium, the results are highly limited.
      08.02.22

    • Bone & Joint Health | Breaking News | Dietary Supplements | Inflammation | Marine Nutraceuticals | Research | Research News
      Krill Oil Study Provides Evidence of Osteoarthritis Benefits

      Krill Oil Study Provides Evidence of Osteoarthritis Benefits

      Adults between the ages of 45 and 60 experienced improved knee pain, stiffness, and physical function.
      07.27.22


    • Breaking News | Cosmeceuticals / Nutricosmetics | Dietary Supplements | Probiotics & Prebiotics | Research | Research News | Skin Health | Supplier News
      Immunobiotic Heat-Killed Bacteria Linked to Skin Benefits

      Immunobiotic Heat-Killed Bacteria Linked to Skin Benefits

      Supplementation with House Wellness Foods’ HK L-137 resulted in skin hydration, and immune response within the skin.
      07.25.22

    • Breaking News | Dietary Supplements | Healthy Aging | Omega-3s | Research | Research News
       Fish Oil Supplementation Effects Exercise Response in Older Women with Sarcopenia

      Fish Oil Supplementation Effects Exercise Response in Older Women with Sarcopenia

      After the intervention, supplementation improved muscle growth and strength compared to placebo.
      07.25.22

    Loading, Please Wait..
    Trending
    • First Day Life Shuts Down Children's Behavioral, Cognitive Health Claims Following Challenge
    • Study Examines Vitamin K2 Content In Cheese
    • Pycnogenol Evidenced To Have Skin Benefits In Dermatology Study
    Breaking News
    • Flower Pollen Extract Benefits Women’s Urinary Incontinence, Study Finds
    • 3i Solutions Announces New Leadership Positions
    • INS Nutra Opens Gummy Manufacturing Facility
    • Vital Nutrients Launches First Vegan Omega Supplement with SPMs
    • Earth Mama Organics Achieves 'Plastic Neutral' Certification
    View Breaking News >
    CURRENT ISSUE

    July/August 2022

    • A Growing Herbal Products Market Still Faces Formidable Threats, Challenges
    • Analytical Testing in Nutraceuticals: Methods and Mindsets to Uphold Quality
    • Nutrition and Flavor: Formulating for Modern Product Preferences
    • Contract Manufacturing: Trials & Tribulations of Today’s Supply Chains
    • How Will the European Green Deal Impact Dietary Supplements?
    • What Do Consumers Know About the Gut Microbiome?
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    Flower Pollen Extract Benefits Women’s Urinary Incontinence, Study Finds
    3i Solutions Announces New Leadership Positions
    INS Nutra Opens Gummy Manufacturing Facility
    Coatings World

    Latest Breaking News From Coatings World

    Lanxess' Entire Value Chain to Become Climate-Neutral
    Custom Cars Featuring PPG DELTRON Refinish System Take Awards at Goodguys 24th Summit
    HGTV Home by Sherwin-Williams Announces 2023 Color Collection of the Year
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    Endologix's AFX2 Endovascular AAA System Earns EU Nod
    Elizabeth Coleon Joins Withings as Chief Marketing Officer
    U.K. Strengthens Medical Device Regulations
    Contract Pharma

    Latest Breaking News From Contract Pharma

    BioIVT Acquires Scottish Drug-metabolizing Enzyme Manufacturer Cypex
    Schott Creates Stand-Alone Company for its Pharma Business
    Marken to Acquire Medical Courier Business of Cedra Express
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    The Body Shop Expands Partnership with Uber
    COSRX Launches Vitamin E Vitalizing Sunscreen
    Weekly Recap: Kylie Makeup Lab Controversy, Glossier Pivots to Retail and Wholesale & More
    Happi

    Latest Breaking News From Happi

    Hallstar To Purchase Lanxess’ Polymer Additives Production Site in Greensboro, NC
    Uber and The Body Shop Expand On-Demand Delivery Partnership Nationwide
    Australia-Based Teeth Whitening Technology Leader White Glo Enters US Market
    Ink World

    Latest Breaking News From Ink World

    Xerox Board of Directors Names Steven Bandrowczak as CEO
    ALTANA AG to Sell Its Stake in dp polar to 3D Systems
    Weekly Recap: Zeller+Gmelin, Epple Druckfarben Lead This Week’s News Stories
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Eukalin acquires Adhesives Specialists
    EyeC unveils new inspection products
    Errol Moebius named VP of IST America
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Weekly Recap: A New Day for Hygiene, Glatfelter Reports Q2 Results & More
    Dyper Achieves B Corp Certification
    Edgewell’s Sales Grow
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    OSSIO Rolls Out OSSIOfiber Suture Anchors in U.S.
    MicroPort Navibot’s SkyWalker System Cleared by FDA
    NuVasive Inc. Reports Q2 2022 Financial Results
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Infineon Technologies AG Offers Secured NFC Tags
    Universal Display Announces 2Q 2022 Financial Results
    Xerox Board of Directors Appoints Steven Bandrowczak as CEO

    Copyright © 2022 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login