By Keith Woelfel, Director of R&D, Caliper Foods04.01.21
While there’s great enthusiasm to make claims around the beneficial effects of CBD, supporting scientific evidence is slim, particularly in humans, and often inconsistent. Discrepancies may be due to differences in CBD bioavailability—CBD is an oil-soluble molecule, difficult for the body to absorb—as well as other factors such as a lack of standardization in CBD formulations, and differences in individual body size and composition.
A recent study conducted by Colorado State University (CSU) compared the absorption rate and bioavailability of three Caliper CBD formulations with two controls that represent the most common ways consumers take CBD today: oil-based CBD tincture and unemulsified CBD isolate.
Methods
Following a double-blind, crossover study design, 15 healthy men and women, ages 21-62, reported to the laboratory on 5 separate days—each time receiving one of the five CBD preparations. All abstained from CBD products for at least 3 days prior to the
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