Sean Moloughney, Editor04.06.21
A new study on Capsimax from OmniActive Health Technologies showed significant increases in resting energy expenditure (REE) following consumption of the concentrated extract of capsaicinoids derived from red chili peppers (Capsicum annum). Findings from this randomized, double-blind, placebo-controlled metabolic rate study, which involved 28 healthy adults, were presented at the Global Summit on Obesity, Diet and Nutrition and published in the Journal of Obesity and Therapeutics.
REE represents the amount of energy expended by a person at rest to maintain the basic and vital functions of the body and accounts for up to 70% of total energy expenditure. Increases in energy expenditure have been linked to reduction in body fat.
According to OmniActive, findings specific to increases in REE are consistent with a previously published study showing similar benefits of Capsimax. In the first metabolic rate study, Capsimax demonstrated that it increased metabolic rate in individuals during fed conditions, while this new study measured the benefits of participants during fasting conditions.
"The primary objective was to measure changes in REE from baseline to post treatment at 1, 2, 3 and 4 hours in comparison to placebo," said Deshanie Rai, PhD, vice president, global scientific and regulatory affairs. "We observed robust and significant changes in REE with Capsimax supplementation during the first 3 hours of the study vs. the placebo group."
"These findings are consistent with our earlier published clinical results demonstrating a benefit of Capsimax on increased metabolic rate and adds another layer of substantiation that should help consumers feel confident that Capsimax is effective either with or without a meal," Rai said.
Perceived changes in body temperature in response to Capsimax supplementation was also measured in the study. "Similar to previous findings, study participants reported an increased feeling of warmth with Capsimax supporting an ‘experiential benefit.’ These results reaffirm Capsimax's efficacy for weight management support, sports nutrition, and beyond,” Rai said.
Sean Moloughney has been the Editor of Nutraceuticals World since 2012. He can be reached at SMoloughney@RodmanMedia.com.
REE represents the amount of energy expended by a person at rest to maintain the basic and vital functions of the body and accounts for up to 70% of total energy expenditure. Increases in energy expenditure have been linked to reduction in body fat.
According to OmniActive, findings specific to increases in REE are consistent with a previously published study showing similar benefits of Capsimax. In the first metabolic rate study, Capsimax demonstrated that it increased metabolic rate in individuals during fed conditions, while this new study measured the benefits of participants during fasting conditions.
"The primary objective was to measure changes in REE from baseline to post treatment at 1, 2, 3 and 4 hours in comparison to placebo," said Deshanie Rai, PhD, vice president, global scientific and regulatory affairs. "We observed robust and significant changes in REE with Capsimax supplementation during the first 3 hours of the study vs. the placebo group."
"These findings are consistent with our earlier published clinical results demonstrating a benefit of Capsimax on increased metabolic rate and adds another layer of substantiation that should help consumers feel confident that Capsimax is effective either with or without a meal," Rai said.
Perceived changes in body temperature in response to Capsimax supplementation was also measured in the study. "Similar to previous findings, study participants reported an increased feeling of warmth with Capsimax supporting an ‘experiential benefit.’ These results reaffirm Capsimax's efficacy for weight management support, sports nutrition, and beyond,” Rai said.
Sean Moloughney has been the Editor of Nutraceuticals World since 2012. He can be reached at SMoloughney@RodmanMedia.com.
