01.14.21
Flavonones are non-nutritive compounds believed to have benefits due to their potent antioxidant and inflammatory-modulating activities. A recent clinical trial which evaluated eriocitrin, a flavonone found abundantly in lemons, concluded that this compound had metabolic benefits in the areas of oxidative stress, inflammation, and the metabolism of glucose and lipids in mice, Ingredients by Nature (IBN) announced.
The study found that at doses as low as 25 mg/kg of eriocitrin, it was efficacious at achieving a number of beneficial responses. Eriocitrin was shown to reduce markers of lipid peroxidation, and delivered a strong antioxidant response by helping the uptake of oxygen radicals and promoting the activation of endogenous defense mechanisms, the authors said. These effects appeared to counteract the consequences of a high-fat diet and helped to prevent a number of consequences associated with metabolic syndrome and other health issues that arise due to obesity.
“Most studies on eriocitrin haven’t explored its effect on obesity-induced metabolic disturbances and, because the global rate of obesity continues to increase, we felt that it was important to examine the topic further,” Dr. Thais Cesar, associate professor of nutrition at Sao Paulo State University, said. “Eriocitrin significantly improved metabolic, inflammatory, and oxidative stress parameters across multiple biomarkers, showing potential to delay the development of inflammatory complications. We look forward to performing additional research on eriocitrin in the future.”
The study also elucidated benefits to glucose and lipid metabolism, especially with reductions in blood glucose, the authors wrote. This benefit has been previously observed in other studies on IBN’s lemon flavonoid blend, Eriomin, which is primarily made up of Eriocitrin. Last year, IBN also received patent certification from the U.S. Patent and Trademark Office for its use of eriocitrin as a method of reducing blood glucose levels.
“As a leading supplier of citrus flavonoids, we put great importance into the continual development of research into these powerful ingredients,” Rob Brewster, president of IBN, said. “Eriocitrin is not commonly recognized as other fruit-derived flavonoids, but the science shows that it is a potent source of health support for a variety of health complications. We look forward to seeing what future research will continue to reveal about it.”
The study found that at doses as low as 25 mg/kg of eriocitrin, it was efficacious at achieving a number of beneficial responses. Eriocitrin was shown to reduce markers of lipid peroxidation, and delivered a strong antioxidant response by helping the uptake of oxygen radicals and promoting the activation of endogenous defense mechanisms, the authors said. These effects appeared to counteract the consequences of a high-fat diet and helped to prevent a number of consequences associated with metabolic syndrome and other health issues that arise due to obesity.
“Most studies on eriocitrin haven’t explored its effect on obesity-induced metabolic disturbances and, because the global rate of obesity continues to increase, we felt that it was important to examine the topic further,” Dr. Thais Cesar, associate professor of nutrition at Sao Paulo State University, said. “Eriocitrin significantly improved metabolic, inflammatory, and oxidative stress parameters across multiple biomarkers, showing potential to delay the development of inflammatory complications. We look forward to performing additional research on eriocitrin in the future.”
The study also elucidated benefits to glucose and lipid metabolism, especially with reductions in blood glucose, the authors wrote. This benefit has been previously observed in other studies on IBN’s lemon flavonoid blend, Eriomin, which is primarily made up of Eriocitrin. Last year, IBN also received patent certification from the U.S. Patent and Trademark Office for its use of eriocitrin as a method of reducing blood glucose levels.
“As a leading supplier of citrus flavonoids, we put great importance into the continual development of research into these powerful ingredients,” Rob Brewster, president of IBN, said. “Eriocitrin is not commonly recognized as other fruit-derived flavonoids, but the science shows that it is a potent source of health support for a variety of health complications. We look forward to seeing what future research will continue to reveal about it.”
