• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    A Clearer Path to Weight Management: The Ozempic Factor

    Under Pressure: Stress and Mental Health Have Taken Center Stage

    Sustainable Business Development: Principles and Strategies for Progress

    Beauty IO MarketWatch: L’Oréal to Define the Next Era of Beauty Tech in CES 2024 Keynote

    Introducing the Happi & Nutraceuticals World Wellness Conference & Tabletop Exhibition
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Glossary
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    GOED Releases Sustainability Report for Omega-3s Industry

    ABC’s Journal HerbalGram Celebrates 40th Anniversary

    Curcumin May Be As Effective as PPI for Indigestion

    Adding Human Milk Component to Formula Linked to Long-term Cognitive Benefits for Babies

    Women in Nutraceuticals Launches Pilot Mentorship Program
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    GOED Releases Sustainability Report for Omega-3s Industry

    ABC’s Journal HerbalGram Celebrates 40th Anniversary

    Curcumin May Be As Effective as PPI for Indigestion

    Weight Loss Products Sold as Supplements Adulterated with Toxic Yellow Oleander

    Nature’s Way Canada Launches NutraSea Omega-3 Kids Chews
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    GOED Releases Sustainability Report for Omega-3s Industry

    ABC’s Journal HerbalGram Celebrates 40th Anniversary

    Curcumin May Be As Effective as PPI for Indigestion

    Adding Human Milk Component to Formula Linked to Long-term Cognitive Benefits for Babies

    Women in Nutraceuticals Launches Pilot Mentorship Program
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    Curcumin May Be As Effective as PPI for Indigestion

    Adding Human Milk Component to Formula Linked to Long-term Cognitive Benefits for Babies

    Weight Loss Products Sold as Supplements Adulterated with Toxic Yellow Oleander

    Nature’s Way Canada Launches NutraSea Omega-3 Kids Chews

    Kyowa Hakko's Immuse Postbiotic Introduced to Mexican Market
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    Aiya America, Inc. (Aiya Matcha)

    American FlexPack

    Premium Labels & Packaging Solutions

    Bioenergy Life Science, Inc. (BLS)

    Applied Food Sciences, Inc.
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    Aiya America, Inc. (Aiya Matcha)

    American FlexPack

    Premium Labels & Packaging Solutions

    Bioenergy Life Science, Inc. (BLS)

    Applied Food Sciences, Inc.
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Breaking News

    ChromaDex Highlights The Latest Research on Niagen

    The patented nicotinamide riboside ingredient is being evaluated for applications including obesity, neurological protection, and immune response to COVID-19.

    ChromaDex Highlights The Latest Research on Niagen
    Niagen appears vital to many more biological functions than those which have been identified since its discovery in 2004.
    05.08.20
    ChromaDex Corp. announced the results of several new studies for its nicotinamide riboside (NR) ingredient, Niagen, which will pave the way for additional research. Niagen is a recently-discovered vitamin B3 found in food, in very trace amounts. For the several years in which Niagen has been commercially available, it has been applied predominantly as an ingredient that may help reverse the signs of aging by converting into NAD+ inside the body, which is believed to act as fuel for converting food into energy, repairing damaged DNA, fortifying cells’ defense systems, and improving circadian rhythym. NAD+ is known to deplete within the body as part of the natural aging process.
     
    Through its research program, called the ChromaDex External Research Program, the patented NR ingredient was provided to research institutions and universities for free, for assessments on Niagen’s ability to increase endogenous levels of NAD+, a critical coenzyme found in every cell of the body, and the potential health implications of such an ingredient.
     
    Obesity
     
    Research published in the American Journal of Clinical Nutrition found that NR supplementation at one gram per day for six weeks in healthy overweight or obese men and women modestly improved body composition, skeletal muscle concentrations of acetyl carnitine (a fatty acid transporter), and an increased metabolic rate during sleep.
     
    COVID-19?
     
    Preclinical research from Dr. Charles Brenner and researchers at three U.S. universities investigated a query as to whether NAD+ has a role in the innate immune response to COVID-19. They found that NAD+ dysregulation occurred in an in vitro model, in the lung tissue of ferrets infected with a zoonotic coronavirus, and in a deceased COVID-19 patient. While further research is underway, these preclinical findings suggest that NAD+ levels were decreased three-fold in infected cells. “The virus and infected cells appear to be playing a tug-of-war with cellular NAD,” Brenner said. “Infected cells activate a set of genes to use NAD for defense while the virus has a specific gene to try to defeat this. These infected cells also have a gene expression program that provides insight into how we may be able to strengthen innate immunity.”
     
    According to researchers, when cells are infected with coronavirus, they specifically seek out NR to replenish NAD+ levels in the face of a viral infection.
     
    In the face of these results, ChromaDex is expediting research materials and data to the scientific community including participants of the ChromaDex External Research Program who are studying NR in relation to COVID-19.
     
    “As a science-based company with a unique NAD boosting molecule and knowing that our cells’ NAD is depleted by viral infections, we take our responsibility seriously and will leverage our science resources to expedite continuing research on the potential impact of Niagen,” Rob Fried, Chromadex CEO, said.
     
    Neurological Protection?
     
    A preclinical study published in Nature Communications investigated the role that NR might have in neurological diseases such as Alzheimer’s and Parkinson’s. In mouse models, it was found that NR significantly increased brain NAD+ levels, partially blocked neurodegeneration, and increased the lifespan of neurodegenerative mice by 30%. The study involved a cross comparison of NR and NMN (nicotinamide mononucleotide) which showed that NMN was not at all effective at raising NAD+ levels in the neurodegenerative mouse model brain.
     
    A Novel Nutrient
     
    As a novel nutritional ingredient, NR is still very much in the investigational stages for its potential applications centered around increasing endogenous NAD+.  A study and review from the journal Nature Metabolism specifically recognized Niagen for its potential as a unique NAD+ boosting agent with regulatory acceptance in a review called “NAD On The Rise Again,” which also confirmed that NR’s close relative, NRH (dihydronicotinamide riboside), has an endogenous presence in the liver, establishing NRH as a natural precursor of NAD+ that causes its natural biosynthesis. ChromaDex also holds intellectual property over NRH and is exploring its scientific potential relative to NR.
     
    The role of boosting NAD+ with NR, and its apparent benefits, were first discovered in 2004 by Dr. Brenner, the head of biochemistry at the University of Iowa and ChromaDex’s chief scientific advisor.
     
    ChromaDex CEO Rob Fried argues that research on NR has pointed to it as being the most efficacious of all NAD+ precursors discovered so far.
     
    “Niagen remains the most effective, consistently safe, and regulatory approved NAD+ precursor on the market,” Fried said. “As the scientific potential of NAD+ has grown, so too has the number of unproven claims and popularity of untested precursors on the market, like NMN, that have not been shown in human clinicals to safely and effectively increase NAD+ levels.”
     
    Related Searches
    • Immune Function
    • Cosmeceuticals / Nutricosmetics
    • Vitamins
    • Research
    Related Knowledge Center
    • Immune Function
    • Dietary Supplements
    • Healthy Aging
    • Quality & Safety
    • Cognitive Function
    • Research
    • Medical Nutrition
    • Cosmeceuticals / Nutricosmetics
    • Vitamins
    Suggested For You
    Women in Nutraceuticals Launches Pilot Mentorship Program Women in Nutraceuticals Launches Pilot Mentorship Program
    Probiotix Health Launches New Heart Health Supplement CholBiome Probiotix Health Launches New Heart Health Supplement CholBiome
    Ashwagandha Extract Linked to Mood and Cognitive Benefits in Several New Studies Ashwagandha Extract Linked to Mood and Cognitive Benefits in Several New Studies
    Clinical Trial Shows Long-Term Joint Health Benefits of PLT’s Boswellia Serrata Extract Clinical Trial Shows Long-Term Joint Health Benefits of PLT’s Boswellia Serrata Extract
    Probiotic Blend Linked to Improved Mood Scores Probiotic Blend Linked to Improved Mood Scores
    Probiotic Strain May Reduce Listeria Infections: Animal Study Probiotic Strain May Reduce Listeria Infections: Animal Study
    ICYMI: Top Content from August 2023 on NutraceuticalsWorld.com ICYMI: Top Content from August 2023 on NutraceuticalsWorld.com
    Ferrous Bisglycinate Linked to Better Efficacy, Fewer Side Effects than Other Iron Salts Ferrous Bisglycinate Linked to Better Efficacy, Fewer Side Effects than Other Iron Salts
    Bioenergy Life Science Partners with Ideal Infusion for Sustained-Release NAD Booster Bioenergy Life Science Partners with Ideal Infusion for Sustained-Release NAD Booster
    Positive Beauty: for People and Planet Positive Beauty: for People and Planet
    Beauty IO MarketWatch: L’Oréal to Define the Next Era of Beauty Tech in CES 2024 Keynote Beauty IO MarketWatch: L’Oréal to Define the Next Era of Beauty Tech in CES 2024 Keynote
    Mind The Gaps: Supporting Voices of BIPOC-Owned Wellness Businesses Mind The Gaps: Supporting Voices of BIPOC-Owned Wellness Businesses
    Novel Creations in Wellness Supplements for Beauty Inside Out Novel Creations in Wellness Supplements for Beauty Inside Out
    Skin Health Supplements Shine as Consumers Seek a More Natural Glow Skin Health Supplements Shine as Consumers Seek a More Natural Glow
    Cuccio Somatology Blends Principles of Yoga and Inner-Outer Wellness into a Global Self-Care Brand Cuccio Somatology Blends Principles of Yoga and Inner-Outer Wellness into a Global Self-Care Brand

    Related Breaking News

    • Breaking News | Dietary Supplements | Industry & Market News
      Women in Nutraceuticals Launches Pilot Mentorship Program

      Women in Nutraceuticals Launches Pilot Mentorship Program

      The six-month program is designed to help senior-level women interested in advancing their career to C-suite and board positions in the nutraceuticals industry.
      09.20.23

    • Breaking News | Cardiovascular Health | Dietary Supplements | Medical Nutrition | Probiotics & Prebiotics | Supplier News | Vitamins
      Probiotix Health Launches New Heart Health Supplement CholBiome

      Probiotix Health Launches New Heart Health Supplement CholBiome

      The formulation contains Lactobacillus plantarum LPLDL, K2Vital Delta from Kappa Bioscience, and thiamine, a form of vitamin B1 with an EFSA heart health claim.
      09.14.23

    • Breaking News | Cognitive Function | Dietary Supplements | Herbs & Botanicals | Mood Health & Sleep | Research | Research News | Supplier News
      Ashwagandha Extract Linked to Mood and Cognitive Benefits in Several New Studies

      Ashwagandha Extract Linked to Mood and Cognitive Benefits in Several New Studies

      Treatment with Specnova’s NooGandha was linked to positive findings in one mood study, two cognition studies, and a safety study.
      09.14.23


    • Bone & Joint Health | Herbs & Botanicals | Inflammation | Research
      Clinical Trial Shows Long-Term Joint Health Benefits of PLT’s Boswellia Serrata Extract

      Clinical Trial Shows Long-Term Joint Health Benefits of PLT’s Boswellia Serrata Extract

      Six-month study on AprèsFlex demonstrated long-term mobility support including cartilage protection.
      09.08.23

    • Breaking News | Dietary Supplements | Mood Health & Sleep | Probiotics & Prebiotics | Research | Research News
      Probiotic Blend Linked to Improved Mood Scores

      Probiotic Blend Linked to Improved Mood Scores

      Those who supplemented with Probiotical’s Bifizen had improved moods sustained through a washout period, as well as increases in circulating serotonin.
      09.07.23

    Loading, Please Wait..
    Trending
    • Soviets Took Probiotics To The Next Level
    • Todd Spear Joins Protein Research As VP Of Sales And Marketing
    • New Technology Converts Sugar In Juice To Fiber
    • Shiitake Mushroom Extract Appears Helpful In HPV Infections
    • HMB And Vitamin D Supplementation Linked To Reduction In Fat Stores
    Breaking News
    • GOED Releases Sustainability Report for Omega-3s Industry
    • ABC’s Journal HerbalGram Celebrates 40th Anniversary
    • Curcumin May Be As Effective as PPI for Indigestion
    • Adding Human Milk Component to Formula Linked to Long-term Cognitive Benefits for Babies
    • Women in Nutraceuticals Launches Pilot Mentorship Program
    View Breaking News >
    CURRENT ISSUE

    September 2023

    • A Clearer Path to Weight Management: The Ozempic Factor
    • Under Pressure: Stress and Mental Health Have Taken Center Stage
    • Sustainable Business Development: Principles and Strategies for Progress
    • BIOHM Health Targets ‘Digestive Plaque’ with Probiotic, Fungus, and Enzyme Formula
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    GOED Releases Sustainability Report for Omega-3s Industry
    ABC’s Journal HerbalGram Celebrates 40th Anniversary
    Curcumin May Be As Effective as PPI for Indigestion
    Coatings World

    Latest Breaking News From Coatings World

    ACS Reports Chameleon Inspired Building Coating
    Substrate Wetting Agent Available from BRB International
    Nouryon Manufacturing Network Transitions to 100% Electricity From Renewable Sources in Brazil
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    MPO's Most-Read Stories This Week—Sept. 23
    Beckman Coulter Helping Labs Comply With Annex 1 Regulation
    FDA Clears MeMed BV Direct From Whole Blood
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Eftilagimod Cleared for Clinical Trial Use in the UK
    Veranova Names William Sanders Global VP of Chemical Development Ops
    Chime, Panolos Partner to Advance Multi-specific Therapeutic Proteins
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Hailey Bieber's Rhode Expands Into Makeup
    Avon Enters Retail Partnership with Superdrug
    IT Award Winners Announced at MakeUp in NY
    Happi

    Latest Breaking News From Happi

    Dental Care Trends and SBLA Beauty's Advertising Claims Under Scrutiny
    OffCourt Debuts in Walmart Stores Nationwide
    Gen Z Is Sweet On Smelling Good
    Ink World

    Latest Breaking News From Ink World

    Cooper Watson Acquires Tower Products
    The Durst Group Awarded Eight 2023 PRINTING United Alliance Pinnacle Awards
    Weekly Recap: Wikoff Color, HP, INX VC Top This Week’s Stories
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    PRX Market debuts, Tower Products acquired and more
    Flexo Wash to exhibit at FTA Fall Technical Conference
    Recyclable, deinkable stand-up pouch wins Gold in Germany
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Weekly Recap: Soft N' Dry Seeks to Expand Private Label Roll Out, Albis Completes Work on Line
    Lenzing Earns EU Ecolabel at Indonesian Plant
    Albis Completes Work On Extra Wide Carding, Blending Line
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    ODT's Most-Read Stories This Week—Sept. 23
    Anika Releases RevoMotion Reverse Shoulder Arthroplasty System
    Exactech's Activit-E Polyethylene OK'ed for Vantage Total Ankle
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    HID to Showcase Future-Proof Solutions at GITEX 2023
    Weekly Recap: Mergers and Acquisitions, IEC’s IME Standards Top This Week’s Stories
    EU-Funded Collaboration Hub Aims to Mainstream Printed Electronics

    Copyright © 2023 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login