• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    Health Products Association - China Executive Director Reflects on Market Dynamics, Challenges

    Blood Sugar Management: Personalized Testing Drives Home The Need for Early Intervention

    New and Evolving Formulation Options Must Be Mindful of Blood Sugar Maintenance

    Tapping Functional Beverages to Meet Modern Wellness Needs

    Adaptogens: Where Ancient Remedies Meet Modern Wellness Products
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    Florida Food Products Acquires Javo

    Roquette Launches Nutralys Rice Protein

    New IADSA Chair Lauds Explorations of Supplementation in Healthcare Policy

    CTRL Launches Meal On-The-Go Bars

    GNC and RealEats Meal Delivery Partnership Expands Nationally
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    Roquette Launches Nutralys Rice Protein

    Upcycled Coffeeberry® Cascara Offers Versatility in Functional Beverage Development

    Study Reveals Low Intake of Tocotrienols in Polish Population

    Combination of Collagen and Boswellia Serrata Shown to Reduce Joint Discomfort

    Nutralliance Adds Eggshell-Derived Ingredients for Beauty and Joint Health to Portfolio
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    Florida Food Products Acquires Javo

    Roquette Launches Nutralys Rice Protein

    New IADSA Chair Lauds Explorations of Supplementation in Healthcare Policy

    CTRL Launches Meal On-The-Go Bars

    Upcycled Coffeeberry® Cascara Offers Versatility in Functional Beverage Development
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    Upcycled Coffeeberry® Cascara Offers Versatility in Functional Beverage Development

    Botanical Gum for Kids Aims to Curb Sugar Cravings

    Combination of Collagen and Boswellia Serrata Shown to Reduce Joint Discomfort

    Childhood Fitness and Obesity Impact Cognition Later in Life, Study Finds

    Nutralliance Adds Eggshell-Derived Ingredients for Beauty and Joint Health to Portfolio
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    KLK OLEO

    Botanic Healthcare LLC

    ESHA Research

    Atlantia Clinical Trials

    Bioactive Resources
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    KLK OLEO

    Botanic Healthcare LLC

    ESHA Research

    Atlantia Clinical Trials

    Bioactive Resources
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Breaking News

    Study Explains Molecular Mechanism for Therapeutic Effects of Cilantro

    Researchers uncovered what enables cilantro to effectively delay certain seizures common in epilepsy and other diseases.

    Study Explains Molecular Mechanism for Therapeutic Effects of Cilantro
    Related CONTENT
    • Study Demonstrates Efficacy of PlusCBD Oil for Sleep, Wellness & Appetite Reduction
    • Moderate Calorie Restriction Can Reduce Heart & Metabolic Risk Factors
    • Natural Formulas Bolster Energy & Vitality
    • Irregular Sleep Linked to Metabolic Disorders
    • Study Links Microbiome Composition to Preterm Birth Risk Among African-American Women
    07.23.19
    Herbs, including cilantro, have a long history of use as folk medicine anticonvulsants. Until now, many of the underlying mechanisms of how the herbs worked remained unknown.  In a new study, researchers uncovered the molecular action that enables cilantro to effectively delay certain seizures common in epilepsy and other diseases. 
     
    The study, published in FASEB Journal, explained the molecular action of cilantro (Coriandrum sativum) as a highly potent KCNQ channel activator. This new understanding may lead to improvements in therapeutics and the development of more efficacious drugs.
     
    “We discovered that cilantro, which has been used as a traditional anticonvulsant medicine, activates a class of potassium channels in the brain to reduce seizure activity,” said Geoff Abbott, PhD, professor of physiology and biophysics at the UC Irvine School of Medicine and principal investigator on the study. “Specifically, we found one component of cilantro, called dodecenal, binds to a specific part of the potassium channels to open them, reducing cellular excitability. This specific discovery is important as it may lead to more effective use of cilantro as an anticonvulsant, or to modifications of dodecenal to develop safer and more effective anticonvulsant drugs.”
     
    Researchers screened cilantro leaf metabolites, revealing that one—the long-chain fatty aldehyde (E)-2-dodecenal—activates multiple potassium channels including the predominant neuronal isoform and the predominant cardiac isoform, which are responsible for regulating electrical activity in the brain and heart. This metabolite was also found to recapitulate the anticonvulsant action of cilantro, delaying certain chemically-induced seizures. The results provide a molecular basis for the therapeutic actions of cilantro and indicate that this ubiquitous culinary herb is surprisingly influential upon clinically important potassium channels.
     
    Documented use of botanical folk medicines stretches back as far as recorded human history. There is DNA evidence, dating back 48,000 years, that suggests the consumption of plants for medicinal use by Homo neanderthalensis. Archaeological evidence, dating back 800,000 years, suggests a non-food use of plants by Homo erectus or similar species. Today, evidence of the efficacy of botanical folk medicines ranges from anecdotal to clinical trials. In many cases, these nutraceuticals are currently consumed, often on a large scale, as foodstuffs or food flavoring. Cilantro, known as coriander in the U.K. is one example. Cilantro has been consumed by human beings for at least 8,000 years. It was found in the tomb of Tutankhamen and is thought to have been cultivated by the ancient Egyptians. 
     
    “In addition to the anticonvulsant properties, cilantro also has reported anti-cancer, anti-inflammatory, anti-fungal, antibacterial, cardioprotective, gastric health and analgesic effects,” said Abbott. “And, the best part is it tastes good!” 
     
    This study was supported by the National Institutes of Health, National Institute of General Medicine Sciences and National Institute of Neurological Disorders and Stroke.  
    Related Searches
    • dna
    • Herb
    • Botanical
    • Health
    Related Knowledge Center
    • Herbs & Botanicals
    • Research
    Suggested For You
    Study Demonstrates Efficacy of PlusCBD Oil for Sleep, Wellness & Appetite Reduction Study Demonstrates Efficacy of PlusCBD Oil for Sleep, Wellness & Appetite Reduction
    Moderate Calorie Restriction Can Reduce Heart & Metabolic Risk Factors Moderate Calorie Restriction Can Reduce Heart & Metabolic Risk Factors
    Natural Formulas Bolster Energy & Vitality Natural Formulas Bolster Energy & Vitality
    Irregular Sleep Linked to Metabolic Disorders Irregular Sleep Linked to Metabolic Disorders
    Study Links Microbiome Composition to Preterm Birth Risk Among African-American Women Study Links Microbiome Composition to Preterm Birth Risk Among African-American Women
    MaquiBright Offers Relief for Eye Dryness & Eye Fatigue Symptoms MaquiBright Offers Relief for Eye Dryness & Eye Fatigue Symptoms
    Study Finds Dietary Cholesterol or Egg Consumption Unrelated to Stroke Risk Study Finds Dietary Cholesterol or Egg Consumption Unrelated to Stroke Risk
    Research Shows Organic Pasteurization Eliminates Pathogens Research Shows Organic Pasteurization Eliminates Pathogens
    Nut Consumption in First Trimester Linked to Improved Neuropsychological Development of Children Nut Consumption in First Trimester Linked to Improved Neuropsychological Development of Children
    Daily Folic Acid Supplement May Reduce Risk of Gestational Diabetes Daily Folic Acid Supplement May Reduce Risk of Gestational Diabetes
    Researchers Explore Engineering Biofilms for Fermented Milk Products Researchers Explore Engineering Biofilms for Fermented Milk Products
    Sabinsa Obtains Patents for ForsLean Coleus Forskohlii Extract Related to Energy Balance Sabinsa Obtains Patents for ForsLean Coleus Forskohlii Extract Related to Energy Balance
    Vitamin D May Protect Obese Children from Asthma Symptoms Associated with Pollution Vitamin D May Protect Obese Children from Asthma Symptoms Associated with Pollution
    Natural Antioxidant Robuvit Improves Symptoms of Infectious Mononucleosis Natural Antioxidant Robuvit Improves Symptoms of Infectious Mononucleosis
    Getting Ahead of the Curve: The Fit Consumer Getting Ahead of the Curve: The Fit Consumer

    Related Breaking News

    • Breaking News | Herbs & Botanicals | Mood Health & Sleep | Research | Research News | Supplier News | Weight Management/Weight Loss
      Study Demonstrates Efficacy of PlusCBD Oil for Sleep, Wellness & Appetite Reduction

      Study Demonstrates Efficacy of PlusCBD Oil for Sleep, Wellness & Appetite Reduction

      Research validates benefits of daily supplementation with CV Sciences’ PlusCBD Oil Gold formula.
      07.18.19

    • Breaking News | Cardiovascular Health | Research | Research News | Weight Management/Weight Loss
      Moderate Calorie Restriction Can Reduce Heart & Metabolic Risk Factors

      Moderate Calorie Restriction Can Reduce Heart & Metabolic Risk Factors

      After two years, participants in the experimental group had reduced daily caloric intake by 12% and maintained, on average, a 10% loss in body weight.
      07.12.19

    • Consumer Trends | Energy | Healthcare Trends | Herbs & Botanicals | Proteins, Peptides, Amino Acids | Sports Nutrition
      Natural Formulas Bolster Energy & Vitality

      Natural Formulas Bolster Energy & Vitality

      Products that can sustain focus and alertness attract all types of consumers, from gamers to weekend warriors.
      By Nutraceuticals World Staff 07.03.19


    • Breaking News | Diabetes & Blood Sugar Management | Healthcare Trends | Mood Health & Sleep | Research | Research News | Weight Management/Weight Loss
      Irregular Sleep Linked to Metabolic Disorders

      Irregular Sleep Linked to Metabolic Disorders

      Obesity, diabetes, high cholesterol more prevalent among irregular sleepers.
      06.07.19

    • Breaking News | Infant & Children's Health | Probiotics & Prebiotics | Research | Research News | Women's Health

      Study Links Microbiome Composition to Preterm Birth Risk Among African-American Women

      Preterm group had lower levels of Lactobacillus crispatus, higher levels of BVAB1 and 12 other bacterial groups.
      06.04.19

    Trending
    • Three Grams Of Omega-3s May Be Optimal Dose For Reducing Blood Pressure
    • 3 grams of Omega-3s May be Optimal Dose for Reducing Blood Pressu
    • Olive/Pomegranate Extract May Improve Dyslipidemia
    Breaking News
    • Florida Food Products Acquires Javo
    • Roquette Launches Nutralys Rice Protein
    • New IADSA Chair Lauds Explorations of Supplementation in Healthcare Policy
    • CTRL Launches Meal On-The-Go Bars
    • GNC and RealEats Meal Delivery Partnership Expands Nationally
    View Breaking News >
    CURRENT ISSUE

    June 2022

    • Tapping Functional Beverages to Meet Modern Wellness Needs
    • Adaptogens: Where Ancient Remedies Meet Modern Wellness Products
    • New and Evolving Formulation Options Must Be Mindful of Blood Sugar Maintenance
    • Health Products Association - China Executive Director Reflects on Market Dynamics, Challenges
    • Blood Sugar Management: Personalized Testing Drives Home The Need for Early Intervention
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    Florida Food Products Acquires Javo
    Roquette Launches Nutralys Rice Protein
    New IADSA Chair Lauds Explorations of Supplementation in Healthcare Policy
    Coatings World

    Latest Breaking News From Coatings World

    The Southern Society for Coatings Technology's 84th Annual Technical Conference A Success
    PPG to Showcase Specialty Automotive, Aerospace Adhesives, Sealants at Adhesives & Bonding Expo
    PPG’s New Paint for a New Start Initiative to Transform 25-plus Schools Worldwide
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    MPO's Most Read Stories This Week—June 25
    Magnetic Insight Announces $17 Million in Series B Funding
    BreatheSuite Adds Brad Fluegel to its Board
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Pierre Fabre and Lonza Enter Manufacturing Agreement
    MasterControl and Elemental Machines Form Biomanufacturing Partnership
    Qosina Strengthens Aseptic Capabilities
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Benefit Exec Joins Madison Reed's Board
    Peroni & Ellis Brooklyn Launch Fragrance Collection Inspired by Italian Spritz Cocktails
    Rhode Is Trending for June, Trendalytics Says
    Happi

    Latest Breaking News From Happi

    Wonder Curl Wins GlossWire's GlossPitch Competition
    Anti-aging Skincare Brand Vitabrid C12 Launches Bestsellers on Amazon
    Botanical Embedded Candles Can Be Fire Hazard, Says National Candle Association
    Ink World

    Latest Breaking News From Ink World

    Weekly Recap: INX’s VC Fund, Screen Industry and Ball Top This Week’s News
    British Coatings Federation Posts Online History
    Orion Announces Price Increases, Reduced Payment Terms
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    PCMC teams with IGT, Fujifilm makes big announcement and more
    Loftware recognized as 'AIDC Company of the Year'
    Schreiner MediPharm highlights sustainability of Needle-Trap technology
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Tranzonic Names VP of Supply Chain
    Ontex Climate Action Targets Approved by Science-Based Targets Initiative
    Suominen Test Center Assesses Biodegradability of Nonwovens
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    ODT's Most-Read Stories This Week—June 25
    3Spine Inc. Receives IDE Approval for U.S. Pivotal Clinical Trial
    Volume-Based Procurement to Reduce Chinese Orthopedic Market Value
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Weekly Recap: eMagin, Applied Materials, and Schott Top This Week’s Stories
    NREL Names Jennifer Logan to Leadership Team as CFO
    National Grid Renewables Orders 2 GW of First Solar Modules

    Copyright © 2022 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login