• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    Nutraceuticals for Men: Muscle Health and Performance Nutrition

    Aging in Place: Healthy Lifestyles Supplement Science-Based Solutions

    Getting an Edge in Esports: Meeting the Health Needs of Competitive Gamers

    Beyond CBD: Cannabis Compounds Warrant Recognition and More Research

    Leveling Out the Energy Segment for Mainstream, and Rethinking Caffeine
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    GOED Creates Infographic Highlighting Omega-3 Health Claims Approved in Europe

    Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board

    Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission

    Choline Alone May Improve Maternal DHA Status During Pregnancy

    Cranberry Consumption Linked to Memory and Neurological Function Improvements
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    GOED Creates Infographic Highlighting Omega-3 Health Claims Approved in Europe

    Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board

    Choline Alone May Improve Maternal DHA Status During Pregnancy

    Cranberry Consumption Linked to Memory and Neurological Function Improvements

    Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    FDA Issues Draft Guidance on NDI Enforcement Discretion

    GOED Creates Infographic Highlighting Omega-3 Health Claims Approved in Europe

    Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board

    Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission

    Choline Alone May Improve Maternal DHA Status During Pregnancy
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board

    Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission

    Choline Alone May Improve Maternal DHA Status During Pregnancy

    Cranberry Consumption Linked to Memory and Neurological Function Improvements

    Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    Botanic Healthcare LLC

    Sabinsa Corporation

    KLK OLEO

    Verdure Sciences

    Nutrition21, LLC
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    Botanic Healthcare LLC

    Sabinsa Corporation

    KLK OLEO

    Verdure Sciences

    Nutrition21, LLC
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Breaking News

    Vitamin K2 Stability Linked with Purity Profile

    Synthetic MK7 showed the lowest purity profile characterized by 23 species accounting for 5.67% of the unknown components.

    Vitamin K2 Stability Linked with Purity Profile
    Related CONTENT
    • Health Logics Debuts Mythocondro Chondroitin Sulfate
    • Direct Compression of Probiotic Tablets with PROSOLV ® EASYtab Nutra
    • Black Cumin Seed Extract Shows Positive Effect on Metabolic Health & Fatty Liver
    • PrimaVie Shilajit May Help Reduce Fatigue & Retain Strength
    • QuickStrip Technology Offers ‘Quick, Convenient, Precise, and Discreet’ Delivery
    05.01.19
    A study published in the journal Molecules shows that the higher purity profile of vitamin K2 as MK7 correlates with enhanced stability in formulations. This finding could explain discrepancies found in finished products analyzed in the worldwide market in recent years.

    The study compared the purity profiles of different raw materials and the results were related to stability assay in normal (12months/25°C/60%RH) and accelerated conditions (6 months/40°C/75% RH) in order to test their performance in the presence of different common excipients. In particular, two naturally fermented MK7 and a synthetic one, all commercially available, were used. 

    All the active ingredients were independently formulated with minerals largely used on the market in combination with MK7. Finally, experimental observations were complemented by comparison of the actual/nominal content of MK7 in different formulations commercially available on the international markets, where the producers state on their labels the source of MK7 used to manufacture the finished products. 

    Data highlighted that different purity profiles corresponded to different stability profiles, where pure products generally showed the highest stability. Moreover, the study explained that patterns of instability could be associated with types of MK7 characterized by different purity profiles. 

    In particular, the multiplicity of chromatographic impurities was frequently observed and consistently associated with lower content of the all-trans isomer (isomeric purity) or with an underestimation of the assay, despite the fact that an overage of the supplement formula is a common practice to minimize the risk of degradation and, consequently, of a lower assay of the formula. Moreover, the study has highlighted that, though it is very likely that menaquinones show a very high thermal stability while they may be degraded following exposure to UV radiation and alkaline compound, the destabilizing effect of the minerals was not identical in the presence of different MK7. The synthetic MK7 showed the lowest purity profile characterized by 23 species accounting for 5.67% of the unknown components. 

    The study also reinforces the concept that MK7 materials, which equally comply to minimal assay and composition characteristics as detailed by the official USP quality standard for dietary ingredients, may be different in terms of their purity profiles due to the presence of cis isomers and other impurities. 

    Commenting on the study, Silvia Pisoni, marketing manager of the Gnosis by Lesaffre said, “VitaMK7 is one of the naturally fermented MK7 ingredient tested in the study, with positive results in line with our current campaign of information about quality and stability. We really believe this work can help all players and actors in the vitamin k2 as MK7 market to shed a light on this amazing ingredient and on its chemical behavior.” 
    Related Searches
    • Vitamin
    • Minerals
    • Fermented
    • Performance
    Related Knowledge Center
    • Testing
    • Quality & Safety
    • Cardiovascular Health
    Suggested For You
    Health Logics Debuts Mythocondro Chondroitin Sulfate Health Logics Debuts Mythocondro Chondroitin Sulfate
    Direct Compression of Probiotic Tablets with PROSOLV ® EASYtab Nutra Direct Compression of Probiotic Tablets with PROSOLV ® EASYtab Nutra
    Black Cumin Seed Extract Shows Positive Effect on Metabolic Health & Fatty Liver Black Cumin Seed Extract Shows Positive Effect on Metabolic Health & Fatty Liver
    PrimaVie Shilajit May Help Reduce Fatigue & Retain Strength PrimaVie Shilajit May Help Reduce Fatigue & Retain Strength
    QuickStrip Technology Offers ‘Quick, Convenient, Precise, and Discreet’ Delivery QuickStrip Technology Offers ‘Quick, Convenient, Precise, and Discreet’ Delivery
    Nutraceutical Brands Find Relief in Outsourcing Manufacturing Nutraceutical Brands Find Relief in Outsourcing Manufacturing
    Creating User-Friendly Oral Dosage Forms Creating User-Friendly Oral Dosage Forms
    Vitamins & Minerals: Traditions in Preventive Health Vitamins & Minerals: Traditions in Preventive Health
    Examining Testing & Certification for Dietary Supplements Examining Testing & Certification for Dietary Supplements
    Lesaffre Completes Full Acquisition of Gnosis Lesaffre Completes Full Acquisition of Gnosis
    Leafy Greens, Berries & Orange Juice May Be Linked to Decreased Memory Loss in Men Leafy Greens, Berries & Orange Juice May Be Linked to Decreased Memory Loss in Men
    Study Reveals Fucoidan Extract Reduces Gut Inflammation Study Reveals Fucoidan Extract Reduces Gut Inflammation
    The Clean Label Tidal Wave: Dosage Delivery Forms Become Critical The Clean Label Tidal Wave: Dosage Delivery Forms Become Critical
    Study Further Supports Wellmune’s Ability to Strengthen Immunity in Athletes Study Further Supports Wellmune’s Ability to Strengthen Immunity in Athletes

    Related Content

    • Bone & Joint Health | Breaking News | Delivery & Dosage Technologies | Dietary Supplements | Products

      Health Logics Debuts Mythocondro Chondroitin Sulfate

      Clinically-tested, vegan formula supports joint health and mobility.
      05.01.19

    • Direct Compression of Probiotic Tablets with PROSOLV ® EASYtab Nutra

      ...

    • Antioxidants | Breaking News | Herbs & Botanicals | Research | Research News | Supplier News | Weight Management/Weight Loss
      Black Cumin Seed Extract Shows Positive Effect on Metabolic Health & Fatty Liver

      Black Cumin Seed Extract Shows Positive Effect on Metabolic Health & Fatty Liver

      Thymoquinone, the main active within the seeds, is a potent antioxidant.
      04.17.19


    • Breaking News | Men's Health | Proteins, Peptides, Amino Acids | Research | Research News | Sports Nutrition | Supplier News
      PrimaVie Shilajit May Help Reduce Fatigue & Retain Strength

      PrimaVie Shilajit May Help Reduce Fatigue & Retain Strength

      Supplementation was found to benefit muscular strength and hydroxyproline levels in recreationally active men.
      04.01.19

    • Delivery & Dosage Technologies | Dietary Supplements
      QuickStrip Technology Offers ‘Quick, Convenient, Precise, and Discreet’ Delivery

      QuickStrip Technology Offers ‘Quick, Convenient, Precise, and Discreet’ Delivery

      Active ingredients are embedded in thin film.
      By Sean Moloughney, Editor 03.19.19

      Trending
      • Vitamin D3, Omega-3s, Exercise May Cumulatively Reduce Cancer Risk In Older Adults | Nutraceuticals World
      • Leaven Essential To Launch Branded Botanical Extracts To Global Markets | Nutraceuticals World
      • Indena’s Meriva Curcumin Supplement May Benefit Kidney Function
      • Vitamin D3, Omega-3s, Exercise May Cumulatively Reduce Cancer Risk in Older Adults
      • Test On Hydrolyzed Collagen Shows Resoundingly High Bioavailability | Nutraceuticals World
      Breaking News
      • GOED Creates Infographic Highlighting Omega-3 Health Claims Approved in Europe
      • Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board
      • Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission
      • Choline Alone May Improve Maternal DHA Status During Pregnancy
      • Cranberry Consumption Linked to Memory and Neurological Function Improvements
      View Breaking News >
      CURRENT ISSUE

      May 2022

      • Aging in Place: Lifestyle Supplements Science-Based Solutions
      • Getting an Edge in Esports: Meeting Health & Nutrition Needs
      • Nutraceuticals for Men: Muscle Health and Performance Nutrition

      Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
      You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

      • About Us
      • Privacy Policy
      • Terms And Conditions
      • Contact Us

      follow us

      Subscribe
      Nutraceuticals World

      Latest Breaking News From Nutraceuticals World

      GOED Creates Infographic Highlighting Omega-3 Health Claims Approved in Europe
      Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board
      Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission
      Coatings World

      Latest Breaking News From Coatings World

      Teknos Receives EcoVadis Gold Medal for Sustainability Performance
      AkzoNobel and Partners Team Up to Hack Carbon Reduction Challenges
      Five PPG Facilities in Ohio Recognized for Sustainability, Health, Safety Practices
      Medical Product Outsourcing

      Latest Breaking News From Medical Product Outsourcing

      Iterative Scopes Expands its Senior Leadership Team
      Viz.ai Raises $100 Million in Series D Funding
      FDA Clears Arterys' AI Mapping and Quantification Tools
      Contract Pharma

      Latest Breaking News From Contract Pharma

      Piramal Pharma Solutions New API Plant in Canada Now Online
      MG America Appoints Claudio Radossi as President
      Catalent Invests $175M to Expand Mfg. Capabilities at Winchester, KY
      Beauty Packaging

      Latest Breaking News From Beauty Packaging

      Authentic Beauty Concept Launches Second-Generation ‘Refill Bar’
      HASK Beauty Enters Exclusive Partnership with Amazon
      Garance Doré Launches Made in France Skincare Line
      Happi

      Latest Breaking News From Happi

      Silab Implements Biodiversity Conservation Project
      Indie Beauty Brand i-On Skincare Releases New Skin Emulsion, AI Diagnostic Tool
      Estée Lauder Companies' New Research on Oxidative Damage, Skin Barrier Function & Hyperpigmentation
      Ink World

      Latest Breaking News From Ink World

      Nazdar Celebrates 100 Years with a New Look
      hubergroup Chemicals Exhibits at Paint India for First Time
      Award for Sustainability: Evonik Receives Platinum Rating Again
      Label & Narrow Web

      Latest Breaking News From Label & Narrow Web

      Specialty announces move to new facility
      Mark Andy hosts dealer's open house in Warsaw
      Nazdar celebrates 100th anniversary with refreshed brand identity
      Nonwovens Industry

      Latest Breaking News From Nonwovens Industry

      3M to Expand in Nebraska
      Nicely Offers Nonwoven Slitters, Winders
      'Right' Hygiene Conference to be Held in June
      Orthopedic Design & Technology

      Latest Breaking News From Orthopedic Design & Technology

      FDA Clears Anika Therapeutics' X-Twist Knotless Fixation System
      Paragon 28 Rolls Out TenoTac 2.0 Hammertoe and Soft Tissue Repair
      Cionic Expands Scientific Advisory Board
      Printed Electronics Now

      Latest Breaking News From Printed Electronics Now

      Evonik Launches New Processing Aids for PV Wafer Cutting
      NREL Creates Highest Efficiency 1-Sun Solar Cell
      eMagin Wins People’s Choice Award at Display Week 2022

      Copyright © 2022 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

      AD BLOCKER DETECTED

      Our website is made possible by displaying online advertisements to our visitors.
      Please consider supporting us by disabling your ad blocker.


      FREE SUBSCRIPTION Already a subscriber? Login