• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    Nutraceuticals for Men: Muscle Health and Performance Nutrition

    Aging in Place: Healthy Lifestyles Supplement Science-Based Solutions

    Getting an Edge in Esports: Meeting the Health Needs of Competitive Gamers

    Beyond CBD: Cannabis Compounds Warrant Recognition and More Research

    Leveling Out the Energy Segment for Mainstream, and Rethinking Caffeine
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board

    Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission

    Choline May Independently Improve Maternal DHA Status During Pregnancy

    Cranberry Consumption Linked to Memory and Neurological Function Improvements

    Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board

    Choline May Independently Improve Maternal DHA Status During Pregnancy

    Cranberry Consumption Linked to Memory and Neurological Function Improvements

    Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain

    Jordan Process Receives Nutrasource ICAP Certification for CBD
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board

    Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission

    Choline May Independently Improve Maternal DHA Status During Pregnancy

    Cranberry Consumption Linked to Memory and Neurological Function Improvements

    Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board

    Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission

    Choline May Independently Improve Maternal DHA Status During Pregnancy

    Cranberry Consumption Linked to Memory and Neurological Function Improvements

    Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    Aiya America, Inc. (Aiya Matcha)

    Sabinsa Corporation

    PhytoGaia Inc

    KLK OLEO

    Verdure Sciences
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    Aiya America, Inc. (Aiya Matcha)

    Sabinsa Corporation

    PhytoGaia Inc

    KLK OLEO

    Verdure Sciences
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Breaking News

    French Grape Seed Extract VX1 Found to Suppress Cancer Pathways

    Researchers suggest findings hold great promise for future therapies.

    Related CONTENT
    • Heart Health Dietary Supplement Market Influences & Opportunities
    • Artemis to Distribute Italian Grape Seed Extract High in Proanthocyanidins
    • Mouse Study Shows Curcumin More Effective for Colitis with Turmeric Essential Oil
    • Scientists Respond to Coverage of Curcumin
    • Canola Oil May Help Reduce Belly Fat and Improve Metabolic Syndrome
    05.10.16
    In the first study of its kind, researchers at the Baylor Scott & White Research Institute, Baylor University Medical Center have demonstrated novel and previously unknown mechanisms of action by which low molecular weight oligomeric proanthocyanins (OPC) from French grape seed extract VX1 help eradicate colorectal cancer cells. The study, titled, “Oligomeric proanthocyanidins inhibit Hippo-YAP pathway and prevent colorectal cancer stem cell formation,” was a poster presentation at the annual American Association for Cancer Research (AACR) meeting in New Orleans, LA, April 16-20, 2016.
     
    "We know that chemotherapy kills cancer cells but leaves behind cancer stem cells that are key to cancer's recurrence and metastasis (spread)," explained Ajay Goel, PhD, senior author of the study. "In this study, we were able to for the first time demonstrate that OPCs can eliminate cancer stem cells, and the mechanism by which they are effective. We found that OPCs target a unique pathway called HIPPO-YAP that is necessary for stem cell survival. We show that OPCs can suppress this pathway, and this is something that has never been shown before." Dr. Goel is Professor, and Director of the Center for Epigenetics and Cancer Prevention, Baylor Scott & White Research Institute, Baylor University Medical Center, Dallas, TX.
     
    "Also, we showed that OPCs cause cell cycle arrest and lock up tumor cells in their growth phase, which eventually leads to cancer cell death," he added. "We found that OPCs target specific microRNAs that lead to cancer suppression. There is a growing interest in miRNA-based pharmaceutical drug development for cancer, though there has not been success. So we are quite gratified and enthused that low molecular weight OPCs can effectively, safely, and inexpensively achieve this goal, which no drug has yet accomplished—and all without the potential side effects and toxicity associated with such treatments.”
     
    Dr. Goel concluded, "While these are pre-clinical findings in cultured cells and animal models, the results may hold great promise for people with colorectal cancer. More human research is needed. However, I think using a tannin-free, low molecular weight OPC grape seed extract may provide excellent benefits.”
     
    It is important to note that the form of grape seed extract used in the study, VX1, has unique specifications for standardization to low molecular weight for proper absorption. It is a tannin-free extract. Therefore, results may not apply to other forms of grape seed without these standardizations.
    Related Searches
    • Cancer
    • Prevention
    • Extract
    • grape seed
    Related Knowledge Center
    • Research
    • Cancer Risk
    Suggested For You
    Heart Health Dietary Supplement Market Influences & Opportunities Heart Health Dietary Supplement Market Influences & Opportunities
    Artemis to Distribute Italian Grape Seed Extract High in Proanthocyanidins Artemis to Distribute Italian Grape Seed Extract High in Proanthocyanidins
    Mouse Study Shows Curcumin More Effective for Colitis with Turmeric Essential Oil Mouse Study Shows Curcumin More Effective for Colitis with Turmeric Essential Oil
    Scientists Respond to Coverage of Curcumin Scientists Respond to Coverage of Curcumin
    Canola Oil May Help Reduce Belly Fat and Improve Metabolic Syndrome Canola Oil May Help Reduce Belly Fat and Improve Metabolic Syndrome
    GNC Honors Former Polyphenolics President Anil Shrikhande GNC Honors Former Polyphenolics President Anil Shrikhande
    2015 Beauty Ingredients Directory 2015 Beauty Ingredients Directory
    Are the Data Underlying the U.S. Dietary Guidelines Flawed? Are the Data Underlying the U.S. Dietary Guidelines Flawed?
    Plant-Derived Compound Targets Cancer Stem Cells Plant-Derived Compound Targets Cancer Stem Cells
    Sensient Flavors Forecasts Flavor Trends For 2015 Sensient Flavors Forecasts Flavor Trends For 2015
    Sweet Potato Leaves May Contain Essential Vitamins Sweet Potato Leaves May Contain Essential Vitamins
    2014 Beauty Ingredients Directory 2014 Beauty Ingredients Directory
    Technologies Open Doors for Oats & Barley in Functional Foods Technologies Open Doors for Oats & Barley in Functional Foods
    Ingredion to Distribute AGT Pulse Flours, Protein and Bran Ingredients Ingredion to Distribute AGT Pulse Flours, Protein and Bran Ingredients
    Technologies Open Doors for Oats and Barley in Functional Foods Technologies Open Doors for Oats and Barley in Functional Foods

    Related Content

    • Cardiovascular Health | Dietary Supplements | Healthcare Trends | Healthy Aging | Herbs & Botanicals | Omega-3s | Probiotics & Prebiotics | Vitamins
      Heart Health Dietary Supplement Market Influences & Opportunities

      Heart Health Dietary Supplement Market Influences & Opportunities

      While product sales have grown modestly, the consumer need for cardiovascular support solutions continues to expand.
      By Danielle Rose, Contributing Writer 11.11.21

    • Artemis to Distribute Italian Grape Seed Extract High in Proanthocyanidins

      Artemis to Distribute Italian Grape Seed Extract High in Proanthocyanidins

      Ecovitis uses proprietary water-based membrane extraction method and an analytical approach.
      10.25.21

    • Breaking News | Digestive Health | Herbs & Botanicals | Research | Research News

      Mouse Study Shows Curcumin More Effective for Colitis with Turmeric Essential Oil

      Combination better at maintaining a healthy body weight, and showed a significant trend to less severe intestinal bleeding.
      04.24.17


    • Antioxidants | Herbs & Botanicals | Research
      Scientists Respond to Coverage of Curcumin

      Scientists Respond to Coverage of Curcumin

      Mini-perspective intended to assess viability of curcumin as a drug candidate.
      02.07.17

    • Breaking News | Functional Foods & Beverages | Research | Research News
      Canola Oil May Help Reduce Belly Fat and Improve Metabolic Syndrome

      Canola Oil May Help Reduce Belly Fat and Improve Metabolic Syndrome

      About 40% of adults in the U.S. have metabolic syndrome.
      11.02.16

      Breaking News
      • Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board
      • Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission
      • Choline May Independently Improve Maternal DHA Status During Pregnancy
      • Cranberry Consumption Linked to Memory and Neurological Function Improvements
      • Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain
      View Breaking News >
      CURRENT ISSUE

      May 2022

      • Aging in Place: Lifestyle Supplements Science-Based Solutions
      • Getting an Edge in Esports: Meeting Health & Nutrition Needs
      • Nutraceuticals for Men: Muscle Health and Performance Nutrition

      Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
      You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

      • About Us
      • Privacy Policy
      • Terms And Conditions
      • Contact Us

      follow us

      Subscribe
      Nutraceuticals World

      Latest Breaking News From Nutraceuticals World

      Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board
      Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission
      Choline May Independently Improve Maternal DHA Status During Pregnancy
      Coatings World

      Latest Breaking News From Coatings World

      Teknos Receives EcoVadis Gold Medal for Sustainability Performance
      AkzoNobel and Partners Team Up to Hack Carbon Reduction Challenges
      Five PPG Facilities in Ohio Recognized for Sustainability, Health, Safety Practices
      Medical Product Outsourcing

      Latest Breaking News From Medical Product Outsourcing

      VenoStent's SelfWrap Bioabsorbable Perivascular Wrap Earns Breakthrough Status
      Guard Medical Closes $11 Million Series B Investment
      OMNIVISION, Silicon Line Partner on Optical Fiber Endoscope Cables
      Contract Pharma

      Latest Breaking News From Contract Pharma

      Catalent Invests $175M to Expand Mfg. Capabilities at Winchester, KY
      Sartorius Expands Manufacturing Site in Tunisia
      BioMoti Partners with Pharma Company to Develop Ovarian Cancer Treatment
      Beauty Packaging

      Latest Breaking News From Beauty Packaging

      Garance Doré Launches Made in France Skincare Line
      The World’s Most Popular Perfumes & Celebrity Fragrances
      Ulta Beauty Launches Retail Media Network
      Happi

      Latest Breaking News From Happi

      Loum Beauty, Rare Beauty Launch #BeautyCares Voices
      ACI Urges Congress To Ensure Funding for EPA’s Office of Chemical Safety and Pollution Prevention
      Dr. Dana’s Nail Renewal System Relaunches Under Rare Beauty Brands
      Ink World

      Latest Breaking News From Ink World

      hubergroup Chemicals Exhibits at Paint India for First Time
      Award for Sustainability: Evonik Receives Platinum Rating Again
      Nazdar Ink Technologies to Showcase Latest Ink Innovations at FESPA Global Print Expo 2022
      Label & Narrow Web

      Latest Breaking News From Label & Narrow Web

      Dantex Group receives accreditation for Pico digital presses
      Heidelberg USA launches new Print Media Performance & Training Center
      Avery Dennison announces Global Supplier Award winners
      Nonwovens Industry

      Latest Breaking News From Nonwovens Industry

      'Right' Hygiene Conference to be Held in June
      Freudenberg to Present Battery Pack and Liquid Absorbers at Battery Show
      H&V Appoints Vice President and General Counsel
      Orthopedic Design & Technology

      Latest Breaking News From Orthopedic Design & Technology

      Paragon 28 Rolls Out TenoTac 2.0 Hammertoe and Soft Tissue Repair
      Cionic Expands Scientific Advisory Board
      First Surgeries Performed Using Globus Medical's Excelsius3D
      Printed Electronics Now

      Latest Breaking News From Printed Electronics Now

      NREL Creates Highest Efficiency 1-Sun Solar Cell
      eMagin Wins People’s Choice Award at Display Week 2022
      Wiliot Launches Battery-Assisted Version of its IoT Pixel Tags

      Copyright © 2022 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

      AD BLOCKER DETECTED

      Our website is made possible by displaying online advertisements to our visitors.
      Please consider supporting us by disabling your ad blocker.


      FREE SUBSCRIPTION Already a subscriber? Login