Dilip Ghosh, PhD, FACN, Director, nutriConnect 01.05.15
A large body of epidemiological and experimental data has demonstrated a direct link between chronic inflammation and complex diseases such as obesity, asthma and allergies, cardiovascular disease, type 2 diabetes, rheumatoid arthritis, bowel disease and several types of cancer.
While chronic diseases are caused by dysregulation of multiple genes, many modern medicines are used based on the modulation of only a single target, and therefore are less likely to be effective. Additionally, these medicines often produce numerous side effects and cannot be consumed over long periods of time. Therefore, the new paradigm proposed for the prevention and treatment of inflammatory chronic diseases either combines multiple single-targeted agents or involves a molecule that can target multiple pathways.
According to one estimate, more than 63% of the anti-cancer drugs introduced over the past 25 years have been natural products or can be traced back to natural sources (Newman & Cragg. Journal of Natural Products, 2007). In addition, some dietary agents have shown potential to inactivate inflammatory molecules by direct binding. For example, curcumin, o
While chronic diseases are caused by dysregulation of multiple genes, many modern medicines are used based on the modulation of only a single target, and therefore are less likely to be effective. Additionally, these medicines often produce numerous side effects and cannot be consumed over long periods of time. Therefore, the new paradigm proposed for the prevention and treatment of inflammatory chronic diseases either combines multiple single-targeted agents or involves a molecule that can target multiple pathways.
According to one estimate, more than 63% of the anti-cancer drugs introduced over the past 25 years have been natural products or can be traced back to natural sources (Newman & Cragg. Journal of Natural Products, 2007). In addition, some dietary agents have shown potential to inactivate inflammatory molecules by direct binding. For example, curcumin, o
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