Concentrated yeast-derived beta-glucan is more easily incorporated into food products than grain beta-glucans, which are found in cereal grains such as oats and barley. Yeast-derived beta-glucan is also more palatable than oat because it is not soluble in water and does not become viscous in water as beta-glucan from oats does. However, oat derived beta-glucan may have a higher therapeutic benefit potential.
The use of beta-glucan is a relatively new practice. Practitioners have used beta-glucan as an immunostimulant or as an adjunct cancer treatment. Beta-glucan is also used for its cholesterol-lowering effects and glycemic (blood sugar) control. In 1997, the U.S. Food and Drug Administration (FDA) passed a ruling that allowed oat bran to be registered as the first cholesterol-reducing food at an amount of 3 grams beta-glucan daily.