• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    Delivering Better Gut Health Supplements

    Delivering Dietary Supplements that Exceed Consumer Expectations

    Green Business Network Seeks Comment on New Certification for Hemp-CBD Businesses

    Sweeteners Market Continues to Broaden with Cleaner Labels and Better Formulations

    Optimizing Gut Health: Unlocking the Gates to Well-Being
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    4-week Fish Oil Regimen Showed Significant Muscular Damage Protection in Recent Study

    Review Covers Role of Vitamin K2 in the ‘Calcium Paradox’

    KD Pharma Acquires Rohner AG Manufacturing Assets

    Thorne Healthtech and PreCon Health to Launch Supplements for Pre-, Post-Impact Brain Health

    Green Leafy Vegetable Intervention Reduces Marker of Colorectal Cancer Risk, Study Finds
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    4-week Fish Oil Regimen Showed Significant Muscular Damage Protection in Recent Study

    Review Covers Role of Vitamin K2 in the ‘Calcium Paradox’

    KD Pharma Acquires Rohner AG Manufacturing Assets

    Green Leafy Vegetable Intervention Reduces Marker of Colorectal Cancer Risk, Study Finds

    Kyowa Hakko Launches Heat-Treated Probiotic Strain for Eye Health
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    4-week Fish Oil Regimen Showed Significant Muscular Damage Protection in Recent Study

    Review Covers Role of Vitamin K2 in the ‘Calcium Paradox’

    KD Pharma Acquires Rohner AG Manufacturing Assets

    Thorne Healthtech and PreCon Health to Launch Supplements for Pre-, Post-Impact Brain Health

    Green Leafy Vegetable Intervention Reduces Marker of Colorectal Cancer Risk, Study Finds
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    4-week Fish Oil Regimen Showed Significant Muscular Damage Protection in Recent Study

    Review Covers Role of Vitamin K2 in the ‘Calcium Paradox’

    Thorne Healthtech and PreCon Health to Launch Supplements for Pre-, Post-Impact Brain Health

    Green Leafy Vegetable Intervention Reduces Marker of Colorectal Cancer Risk, Study Finds

    Kyowa Hakko Launches Heat-Treated Probiotic Strain for Eye Health
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    Aiya America (Matcha by Aiya)

    Gencor

    Indena USA, Inc.

    Sabinsa Corporation

    Vesta Nutra
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    Bioenergy Life Science, Inc. (BLS)

    Aiya America (Matcha by Aiya)

    Indena USA, Inc.

    Sabinsa Corporation

    Chenland Nutritionals Inc.
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • eBook
    • Infographics
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Features

    CROs: Driving Research Forward

    The uptick in business for CROs is a positive indication that dietary supplement and functional food companies are doing more research on their products.

    Related CONTENT
    • ChromaDex
    • Transforming Health with Nature’s Sunshine
    • Understanding FTC Standards for Claims Substantiation
    • TREHA Trehalose Available As ‘Natural Flavor’
    • ConsumerLab.com Tests Popular Vitamin D Supplements
    Rebecca Wright05.03.10
    Research has been a big question mark for nutraceutical companies during the last decade for a variety of reasons—no financial incentives, no market protection, borrowing data is easier, etc. But finally, according to many experts, the industry is making progress, largely through the assistance of Contract Research Organizations (CROs).
     
    Offering a bright view of the industry’s evolution, Gitte Jensen, research director, NIS Labs, Inc., Klamath Falls, OR, said today’s companies are dedicated to developing a serious research portfolio. And, despite increased regulatory action, she said, “Our clients are not afraid of exploring new concepts and I see a number of them setting new trends.”

    As far as the industry report card goes, Ms. Jensen added, “I would give the industry an ‘A’ for progress, but a ‘B+’ to ‘B ’for where things stand right now. We need to protect the niche for complex foods and natural products and spend the extra money to get research designed specifically for this industry.”

    Going into more detail on some of the recent hurdles, Andrew Shao, PhD, senior vice president, Scientific & Regulatory Affairs, Council for Responsible Nutrition (CRN), Washington, D.C., explained, “Some companies are beginning to get the message that ‘borrowed’ or ‘pirated’ science is not in their best interest. However, in most cases, the incentive is still not there for a commitment to invest in R&D.”

    Dr. Shao also believes the narrow focus on price at the expense of quality and science continues to pervade in many circles, further undermining the long-term health of the industry.

    Kelly Nichols, communications coordinator, NSF International, Ann Arbor, MI, said some of the confusion stems from label claims and terminology. “One of the major issues that the industry is dealing with is the confusion over health and label claims; over what is a dietary supplement and what is a functional food (FDA has no definition for a functional food),” she said. “These issues can be prevented by performing double-blind clinical trials on the dietary ingredient for which the health or structure-function claim is made.”

    Najla Guthrie, president and CEO, KGK Synergize, London, Ontario, Canada, offered a similar view. “The biggest deterrent for conducting research in our industry is that the competition may benefit from the science our clients are paying to conduct. We advise our clients to conduct research on their finished branded products so they can limit competitors from borrowing their science,” she said.

    But the reality is, according to Jillian Capodice, vice president, Nutraceutical Medical Research (NMR), White Plains, NY, research will always be necessary in order for novel, safe and effective products to be developed and delivered to the marketplace. With regard to both the dietary supplement and functional food markets specifically, Ms. Capodice believes conducting prospective, evidence-based research will likely become a crucial industry standard.

    However, the tricky part with clinical work, said Doug Kalman, RD, director of nutrition research, Miami Research Associates (MRA), Miami, FL, is making sure the objective doesn’t cross the line into disease. “When you do a clinical trial on a dietary supplement that is evaluating its effects on a disease or condition, it makes that study into a drug study. Therefore, you need to file an investigational new drug (IND) application with FDA,” he said, adding, “And lately, FDA has been saying that unless you are talking about quality of life or performance enhancement, you need to file an IND.”

    But before a company even gets to the clinical trial stage, it must understand how its material or products behave from a chemistry standpoint. “When planning clinicals, some companies overlook how the substance is characterized,” said Frank Jaksch, CEO, ChromaDex, Irvine, CA. “This is where there is a surprising amount of failure.”

    These aren’t the only areas nutraceutical companies are coming up short. The R&D department, where research begins, is, by most accounts, understaffed and underfunded. Allocating the appropriate resources could alleviate many of the pressures companies face in today’s competitive, highly scrutinized business environment.

    Skimpy R&D Budgets

    R&D is a crucial part of any company’s business, whatever the industry. For one thing, it helps secure plans for the future generation of products. Unfortunately, to some degree, the importance of R&D is lost on many nutraceutical companies. Mr. Jaksch of ChromaDex explained. “There is still a fairly large disconnect in terms of what needs to be done on the research end to get products to market. And one of the reasons is that research is often improperly integrated into the R&D process.”

    Currently, Mr. Jaksch estimates that nutraceuticals companies dedicate about 1-2% of revenues to R&D—which is on the high end. However, he said, “If you take the average supplement company, worth between $100-150 million, and it is making the standard commitment of 5-10% toward R&D, it should be setting aside $10-15 million per year. But I don’t know many companies that spend $5, $10 or $15 million on R&D.”

    On the bright side, he said, there is a paradigm shift going on and money is coming into the industry. “Private equity companies are integrating change and reallocating budgets and putting money where it belongs.”

    Another problem, said Dr. Sidney Sudberg, laboratory director, Alkemists Pharmaceuticals, Costa Mesa, CA, is that many companies are still driven by marketing, as opposed to science. “While there are some innovative companies seeking out the design and development of new compounds or products, most are just reformulating their products to get them to market faster,” he said. “The mindset of the dietary supplement industry at large is still being driven by marketing and less so by efficacy or safety. That said, cost is probably the number one barrier to moving forward on a true research project.”

    Despite the money needed for clinical trials, it is essential to get these studies done, said CRN’s Dr. Shao. “Too often these studies are cut back or cut out in favor of placing resources toward marketing efforts,” he said. “What some companies fail to realize is that these trials become the marketing.”

    Speaking of cost, Joerg Gruenwald, president, analyze & realize ag, a CRO based in Berlin, Germany, discussed the price range for certain types of research. “In vitro studies are the cheapest to see some first effects ($5000-$20,000 and more); in vivo animal studies are in the middle ($20,000-$50,000 and more); and clinical trials are the most expensive but offer the most value for the money ($100,000-$500,000 and more, depending on the number of participants, length of the study, parameters, etc.).”

    Due to the limiting effects of price, most companies are conducting smaller studies. In fact, Darryl Sullivan, scientific director, Covance, Madison, WI, said most of the companies he works with are looking to differentiate their products in terms of quality or superiority, instead of pursuing large efficacy studies.

    However, he doesn’t believe conducting a large efficacy trial would translate into wasted dollars. On the contrary, he thinks a company would actually stand in very high regard with consumers if it chose to substantiate the health benefits of its products.

    Another option, according to Mr. Sullivan, is getting the industry to work together on conducting studies. “I think if there was enough investment from industry to support various product families (e.g., probiotics, omega 3s, ginseng, etc.), there would be a lot of benefit in that,” he said.

    MRA’s Mr. Kalman believes the major reason companies are reluctant to sponsor direct research on their products or ingredients is that the claims they are typically pursuing are too expensive.
     
    Also, he said, right now there is more reactive research going on, rather than proactive research. “I think there is a low percentage of companies looking to do studies and develop IP (intellectual property) for the purity of science. Most companies are compelled to do the research after the fact, in response to letters from attorneys or FDA and FTC.”

    Where the Action is

    Dr. Gruenwald of analyze & realize said there’s a broad range of companies performing clinical trials today, from ingredient companies aiming for proprietary claims, to supplement, functional food and herbal companies looking to substantiate claims. He said many are also interested in safety studies.
     
    However, many experts see an increase in research activity as it pertains to functional foods. “I think there is a lot of momentum behind food becoming more functional. That train has left the station and everyone wants to be on board. And companies are throwing a lot of dollars into researching that category,” said Mr. Jaksch of ChromaDex.
     
    But, he warned, “Regulators might soon make sweeping changes as far as functional food products are concerned, because they don’t seem to like the ‘tweener’ category of functional foods.”

    For Alex Schauss, PhD, FACN, senior research director, Natural and Medicinal Products Research, AIBMR Life Sciences, Inc., Puyallup, WA, there is no question that a dramatic increase in R&D has shifted to the functional food sector. As a result, he said, “This places emphasis on substantiating the safety of the ingredients that go into food. In this vein, GRAS (Generally Recognized as Safe) self-affirmation will continue to be a critical milestone for companies.”
     
    Offering some specifics on functional food research, Covance’s Mr. Sullivan said, “There is a lot of effort going toward changing the composition of food products with some of the designer fibers. There is also a lot of research looking into the stability of vitamins in functional foods and the wide use of pre/probiotics in cereals and yogurts.”

    “There will be a lot of interesting products coming out in the next several months,” Mr. Sullivan added.
     
    According to MRA’s Mr. Kalman, companies that enlist his research services are interested in probiotics, omega 3s and products that modulate stress response, followed by ingredients for anti-inflammatory applications or exercise recovery effects. And most of the studies, he said, are designed to substantiate marketing.

    On the horizon, Dr. Schauss said, are new biotechnologies, or as he likes to call them, “tools that we can use to understand how components in foods favorably affect human health.”
     
    For example, he said, “The field of epigenetics (i.e., nutritional genomics) is helping us to understand how genes influence ‘youth proteins’ when exposed to a food or ingredient. We’ve used these technologies to unravel the mechanisms of action on how they work in terms of genes, cell signaling, etc. This helps us understand why a functional food works and provides us information on which markers to measure in clinical trials.”
     
    Finding the Right Protection


    The best way a company can protect itself in the market is to know as much as possible before entering into a relationship with a CRO. CRN’s Dr. Shao explained, “First, define as best as possible what it is you need—the more well defined, the more likely you will be to avoid some of the problems mentioned previously. Also, determine the company’s stance on publication of results. For a relatively new product with little data generated thus far, companies may want to choose the conservative route of not publishing.”
     
    Next, Dr. Shao said, begin the search for a CRO by using referrals from other companies and trade associations. “Choose the CRO based on your needs and the firm’s area of expertise,” he said. “Some CROs specialize in weight loss studies, others in cosmetic studies, and so on. Be sure to choose a firm that is well versed in your area of interest.”

    Dr. Shao also says never go with a CRO you don’t know without visiting the facility first. “You need to see their capabilities, including staff and equipment. For example, if you intend to study the effects of your product on lean body mass, or LBM, then be sure the firm has a DEXA machine, or some other reliable means to measure LBM,” he said.

    Finally, when it comes time to review the contract, Dr. Shao said be sure all the deliverables are spelled out clearly, including data capture and analysis and timeline. Also, the contract must include a confidentiality agreement, and if the company wants to keep control of the data and not publish, this should be spelled out explicitly.

    Fortunately, Dr. Shao said most CROs are in business to do contract work—analogous to a contract laboratory that does analytical or quality control work for companies—and have little interest in either IP or profiting from the products on which they perform studies. In other words, patents and claims are not an issue for them.

    The more important message for companies, Dr. Shao said, is that they have their IP insulated and protected as quickly and thoroughly as possible, no matter whom they are dealing with on the outside.
     
    It is also important to determine why a CRO is needed. Is the need a follow-up clinical trial to validate previous results on an established product? Or is the product in an earlier stage of the R&D process, for which more developmental work is needed?
     
    And what about the right to publish data—whatever the outcome—from a clinical trial? Dr. Shao says some firms include a clause in their standard contract that gives them the right to publish the results of the research. “This is often a problem for companies researching new products, where the proper form, dose, duration of use and characterization of the product have yet to be optimized. So publicizing the research findings from early versions of products can have a stimulating or stigmatizing effect (depending on the outcome) on future commercial success,” he explained. “The downside of companies keeping sole control of the data, is that studies tend to be published only when they are positive, which skews the evidence base (also referred to as ‘publication bias’).”

    Where Does the Industry Go From Here?


    For the future, MRA’s Mr. Kalman believes the nutraceuticals industry is headed for mandated research in the form of human clinical trials and product-specific studies.

    According to Dr. Gruenwald of analyze & realize, this is already the case in Europe. “Research will be needed for product differentiation and claim support, specifically placebo-controlled, double-blind studies in humans. In Europe this is already happening and only clinically supported claims will be permitted in the future.”

    The good news is many companies are realizing the importance of research, regardless of the regulatory environment. “Ten years ago there were only a handful of companies conducting research,” commented Covance’s Mr. Sullivan. “Now most large and many mid-sized companies are exploring or doing some level of research because the value is more recognized.

    “The other positive,” Mr. Sullivan continued, “is that the industry is working more closely. A decade ago they wouldn’t even talk to each other.”

    Mr. Jaksch of ChromaDex, who calls his company “the CRO for the CRO,” said, “The goal at the end of the day is to make a more consistent product, especially now since that is what we are getting beaten up about in the press. What you will be able to say about research in this industry in five years depends on how hard FDA cracks down and how far companies push the envelope.”

    Sharing a different perspective, CRN’s Dr. Shao said, “The promise of supplements is in health maintenance and prevention. These outcomes are very difficult—in some cases impossible—to demonstrate in clinical trials. The biggest key to the future of product claims, and the industry’s ability to demonstrate the benefits of its products is biomarkers. Biomarkers as indicators of wellness and surrogate endpoints of disease are desperately needed to allow smaller and shorter (i.e., more affordable) human trials to be conducted.”

    Dr. Shao feels biomarkers represent intermediate or short-term measurements of a product’s effect or benefit. Without these, he says trials are too costly and too complex. Adding to the problem is that there are currently no validated biomarkers for wellness, and there are only a handful of validated biomarkers as surrogate endpoints for chronic disease. This, according to Dr. Shao, is where the government can lend a hand.

    “The government can help the process by funding the development and validation of more biomarkers. FDA is actually doing this by funding an IOM (Institute of Medicine) expert committee, whose report is due out this month; they are charged with developing a scientific framework FDA can use to validate more biomarkers. It will be a while (several years) before more biomarkers are validated, but at least this is a start.
     
    “The government can also assist by developing a research paradigm that is better designed to assess the effects of nutrients and bioactives in humans,” Dr. Shao added. “Today we rely on evidence-based medicine, which was developed to assess the effects of drugs. Clearly this is not the best approach to use for nutrients and bioactives.”            

    Related Searches
    • Nutrition
    • Health
    • Proteins
    • Weight Loss
    Related Knowledge Center
    • Regulations
    • Quality & Safety
    • Testing
    Suggested For You
    ChromaDex ChromaDex
    Understanding FTC Standards for Claims Substantiation Understanding FTC Standards for Claims Substantiation
    Transforming Health with Nature’s Sunshine Transforming Health with Nature’s Sunshine
    TREHA Trehalose Available As ‘Natural Flavor’ TREHA Trehalose Available As ‘Natural Flavor’
    ConsumerLab.com Tests Popular Vitamin D Supplements ConsumerLab.com Tests Popular Vitamin D Supplements
    Gottlieb Confirmed to Lead FDA Gottlieb Confirmed to Lead FDA
    Experts Call for Holistic Approaches to Nutrition Experts Call for Holistic Approaches to Nutrition
    Report Highlights Safety Data on Bioactive Nutrients Report Highlights Safety Data on Bioactive Nutrients
    NattoPharma Hires Sales Manager, Americas NattoPharma Hires Sales Manager, Americas
    ChromaDex Adds to Executive Team ChromaDex Adds to Executive Team
    Obesity-Related Clinical Study of NIAGEN Commences Obesity-Related Clinical Study of NIAGEN Commences
    ChromaDex Enters Retail Commercialization Deal With BPI Sports ChromaDex Enters Retail Commercialization Deal With BPI Sports
    Brassica Gains GRAS Status for truebroc Glucoraphanin Brassica Gains GRAS Status for truebroc Glucoraphanin
    Physicians Take and Recommend Several Supplements for Overall Wellness Physicians Take and Recommend Several Supplements for Overall Wellness
    IOM Sets New DRIs for Calcium & Vitamin D IOM Sets New DRIs for Calcium & Vitamin D

    Related Features

    • Cognitive Function | Dietary Supplements | Digestive Health | Enzymes | Fiber & Carbohydrates | Healthcare Trends | Immune Function | Probiotics & Prebiotics | Research
      Optimizing Gut Health: Unlocking the Gates to Well-Being

      Optimizing Gut Health: Unlocking the Gates to Well-Being

      Tied to so many facets of wellness, the gut microbiome will continue to be an attractive target for nutritional products.
      By Sean Moloughney, Editor 04.08.21

    • Consumer Trends | Diabetes & Blood Sugar Management | Functional Foods & Beverages | Healthcare Trends | Sweeteners
      Sweeteners Market Continues to Broaden with Cleaner Labels and Better Formulations

      Sweeteners Market Continues to Broaden with Cleaner Labels and Better Formulations

      Innovation of sugar alternatives is accelerating as edging sugars out of the equation becomes increasingly popular.
      By Mike Montemarano, Associate Editor 04.08.21

    • Herbs & Botanicals | Quality & Safety | Regulations
      Green Business Network Seeks Comment on New Certification for Hemp-CBD Businesses

      Green Business Network Seeks Comment on New Certification for Hemp-CBD Businesses

      The draft standard addresses social and environmental initiatives in 10 different categories.
      By Fran Teplitz, Executive Co-Director, Green America 04.08.21


    • Delivery & Dosage Technologies | Dietary Supplements | Probiotics & Prebiotics | Quality & Safety
      Delivering Better Gut Health Supplements

      Delivering Better Gut Health Supplements

      Processing controls for raw materials, manufacturing, consumer packaging and more will help ensure best-in-class product performance.
      By Scott Steinford, CEO, Health Wright Products 04.08.21

    • Consumer Trends | Delivery & Dosage Technologies | Healthcare Trends | Herbs & Botanicals
      Global Cannabis Sales Surpass $21 Billion in 2020

      Global Cannabis Sales Surpass $21 Billion in 2020

      Market news in the CBD industry.
      By Sean Moloughney, Editor 04.01.21

    • Consumer Trends | Dietary Supplements | Herbs & Botanicals | Regulations
      Untapped Potential: CBD Food & Supplement Market Still in Regulatory Limbo

      Untapped Potential: CBD Food & Supplement Market Still in Regulatory Limbo

      Without a federal regulatory framework for hemp-derived CBD dietary supplements, stakeholders across the value chain are feeling the effects.
      By Sean Moloughney, Editor 04.01.21


    • Consumer Trends | Cosmeceuticals / Nutricosmetics | Healthcare Trends | Packaging
      A CBD Packaging Evolution

      A CBD Packaging Evolution

      With a flurry of CBD entries in the cosmetic and personal care sectors, business is booming and packaging interest is high—especially for sustainable options.
      By Joanna Cosgrove, Contributing Writer 04.01.21

    • Dietary Supplements | Herbs & Botanicals | Quality & Safety | Regulations
      USDA’s Final Rule on Hemp: Experts Discuss Ramifications

      USDA’s Final Rule on Hemp: Experts Discuss Ramifications

      There are mixed opinions coming from the industry on new regulations that will replace those issued in the interim.
      By Mike Montemarano, Associate Editor, Nutraceuticals World 04.01.21

    • Cosmeceuticals / Nutricosmetics | Delivery & Dosage Technologies | Healthcare Trends | Herbs & Botanicals
      Is Cannabidiol Coming to Your City or Hamlet?

      Is Cannabidiol Coming to Your City or Hamlet?

      CBD is the talk of the town these days. But before formulators take part in all of this madness, there are many questions to be answered.
      By Jules Zecchino, Simply Active Cosmetics, Inc. 04.01.21


    • Cosmeceuticals / Nutricosmetics | Healthcare Trends | Herbs & Botanicals | Skin Health
      Mary Jane’s Botanicals: Unique Formulations Hand-Crafted with Premium Ingredients

      Mary Jane’s Botanicals: Unique Formulations Hand-Crafted with Premium Ingredients

      Dahlia Mertens discusses the early days of topical cannabis products, the CBD bubble, and how she’s striving to improve people’s lives.
      By Sheldon Baker, Area Code 420 04.01.21

    • Cosmeceuticals / Nutricosmetics | Delivery & Dosage Technologies | Healthcare Trends | Herbs & Botanicals | Quality & Safety | Regulations
      The Cannabis Glow Up

      The Cannabis Glow Up

      The notorious plant rises from its troubled history to provide new possibilities in cosmetics.
      By Nicole Foss, MBA, MSN, RN, NeXtraction 04.01.21

    • Delivery & Dosage Technologies | Herbs & Botanicals | Research
      Supporting CBD Science: The Path to Claims

      Supporting CBD Science: The Path to Claims

      Pharmacokinetics study showed Caliper CBD products absorbed faster than CBD oil and isolate.
      By Keith Woelfel, Director of R&D, Caliper Foods 04.01.21


    • Consumer Trends | Dietary Supplements | Healthcare Trends | Healthy Aging | Immune Function | Research
      Personalized Nutrition: Science & Innovation Bring Concept to Life

      Personalized Nutrition: Science & Innovation Bring Concept to Life

      This rapidly developing field could be positioned to catalyze a new health paradigm.
      By Sean Moloughney, Editor 03.03.21

    • Antioxidants | Dietary Supplements | Energy | Eye Health | Healthy Aging | Herbs & Botanicals | Immune Function | Vitamins
      Antioxidants Adapt to New Growth Avenues

      Antioxidants Adapt to New Growth Avenues

      Brands have opportunities to reach consumers in search of general health and wellness protection, as well as those who opt for targeted solutions.
      By Sean Moloughney, Editor 03.03.21

    • Consumer Trends | Delivery & Dosage Technologies | Dietary Supplements | Healthcare Trends | Healthy Aging | Nutrition Bars & Snacks | Proteins, Peptides, Amino Acids | Sports Nutrition | Weight Management/Weight Loss
      Following the Ascent of Alternative Proteins

      Following the Ascent of Alternative Proteins

      As the protein palate of global consumers turns greener, concerted efforts to create nutritionally optimized, appealing options abound.
      By Mike Montemarano, Associate Editor 03.03.21

    Trending
    • Meta-analysis Determines HMB Supplementation Promotes Healthy Muscle Mass In Older Adults
    • Innovative Probiotic Launches
    • Kyowa Hakko Launches Heat-Treated Probiotic Strain For Eye Health
    • Nutritional Complex Evidenced To Reduce Preterm Birth
    • Thorne Healthtech And PreCon Health To Launch Supplements For Pre-, Post-Impact Brain Health
    Breaking News
    • 4-week Fish Oil Regimen Showed Significant Muscular Damage Protection in Recent Study
    • Review Covers Role of Vitamin K2 in the ‘Calcium Paradox’
    • KD Pharma Acquires Rohner AG Manufacturing Assets
    • Thorne Healthtech and PreCon Health to Launch Supplements for Pre-, Post-Impact Brain Health
    • Green Leafy Vegetable Intervention Reduces Marker of Colorectal Cancer Risk, Study Finds
    View Breaking News >
    CURRENT ISSUE

    April 2021

    • Delivering Better Gut Health Supplements
    • Optimizing Gut Health: Unlocking the Gates to Well-Being
    • Sweeteners Market Continues to Broaden with Cleaner Labels and Better Formulations
    • Green Business Network Seeks Comment on New Certification for Hemp-CBD Businesses
    • Delivering Dietary Supplements that Exceed Consumer Expectations
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    4-week Fish Oil Regimen Showed Significant Muscular Damage Protection in Recent Study
    Review Covers Role of Vitamin K2 in the ‘Calcium Paradox’
    KD Pharma Acquires Rohner AG Manufacturing Assets
    Coatings World

    Latest Breaking News From Coatings World

    Jebsen & Jessen, Innospec Sign Distribution Agreement
    Sika Expands Production Capacity in Qatar
    Sto Corp. ISO Certifications Extended
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    MICRO Expands with New Facility in Costa Rica
    DiaSorin to Buy Luminex for $1.8B
    Endologix Acquires PQ Bypass
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Catalent Biologics Completes Madison Expansion
    Lonza Expands PyroTec PRO for Endotoxin Testing
    FDA Accepts Airway Therapeutics’ IND for COVID Treatment
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Revieve Launches Skin Coach
    Carlyle Group Acquires Majority Stake in Beautycounter
    The Honest Co. Files for an Initial Public Offering
    Happi

    Latest Breaking News From Happi

    Babor Professional Skin Care Names McCaffrey as Vice President of Sales
    Diamond Chemical Appoints Technical Service Representative
    Carlyle To Acquire Majority Stake in Beautycounter
    Ink World

    Latest Breaking News From Ink World

    Kumon North America Adds Speedmaster XL 106 from Heidelberg
    SE-DA Invests in Kornit Presto S
    Iron Oxide Pigments Market to Register 4.7% CAGR from 2021 to 2028: GVR
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Enprom helps converter respond to flexible packaging needs
    anytron assists medical device company with labeling
    Dantex debuts new capabilities with white ink opacity
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Aries Face Masks Meet ASTM Standards
    Tufropes Launches Inherently Antibacterial and Antimicrobial Spunbond
    NXTNano Adding Three Lines
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    GreenBone Ortho Closes 10 Million Euros Series B Funding Round
    SynerFuse, Cirtec Medical Partner to Develop Back Pain Management Device
    New Biosealant Could Stabilize Cartilage, Boost Healing After Injury
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Virtual ASMC 2021 Spotlights Advanced Semiconductor Manufacturing Excellence
    First Solar Series 6 CuRe has Industry’s Lowest Warranted Degradation Rate
    SEMI: 2020 Global Semiconductor Equipment Sales Surge 19% to Industry Record $71.2 Billion

    Copyright © 2021 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login