04.01.04
BioCell Technology LLC has released results from a double-blind clinical study showing that the naturally occurring hyaluronic acid (HA) in the BioCell Collagen II® product has significant peak absorption and steady state bioavailability in normal volunteer subjects. In a 36-hour peak absorption study using a single dose, BioCell Collagen II HA significantly increased in the blood in four hours and peaked at a level 7008.62% above control in 12 hours. In the blood, the HA was rapidly metabolized to two metabolites 1/600th the size of the ingested HA. In a 28-day steady state bioavailability study using a constant daily dose, after seven days, BioCell Collagen II HA and its metabolites in the blood became stable and these metabolites remained significantly increased throughout the balance of the study (HA at 3542.58% above control and HA metabolite at 11890.15% above control).