Source: Epidemiology, November 2005; 16(6):772-9.
Research: In this Massachusetts hospital-based case-control study of 923 patients with lung cancer and 1125 healthy controls, researchers studied the associations between dietary iron, zinc, and calcium intake and the risk of lung cancer. Dietary intake was assessed at the time of recruitment (1992 to 2000) with the use of a 126-item semi-quantitative food-frequency questionnaire. Researchers analyzed the data using multiple logistic regression models adjusting for smoking history and other potential risk factors.
Results: The associations between dietary micronutrients intake and lung cancer risk were stronger among current smokers than among former smokers. When researchers examined intake from supplements as well as diet, associations were similar to those for diet alone. Researchers concluded that dietary iron, zinc and calcium may play an important role in the development of lung cancer, especially among current smokers, but that these results need to be confirmed in large prospective studies.