• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    Nutraceuticals for Men: Muscle Health and Performance Nutrition

    Aging in Place: Healthy Lifestyles Supplement Science-Based Solutions

    Getting an Edge in Esports: Meeting the Health Needs of Competitive Gamers

    Beyond CBD: Cannabis Compounds Warrant Recognition and More Research

    Leveling Out the Energy Segment for Mainstream, and Rethinking Caffeine
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain

    Jordan Process Receives Nutrasource ICAP Certification for CBD

    FDA Warns About Steroids or Steroid-Like Substances in Bodybuilding Supplements

    Nootropics and Adaptogens Respond to Demand for Mind and Mood Support

    Sabinsa Honors 70th Anniversary of Diplomacy Between India and Japan
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain

    Jordan Process Receives Nutrasource ICAP Certification for CBD

    Nootropics and Adaptogens Respond to Demand for Mind and Mood Support

    Sabinsa Honors 70th Anniversary of Diplomacy Between India and Japan

    Solvay Invests in Suanfarma’s Vanillin Production
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain

    Jordan Process Receives Nutrasource ICAP Certification for CBD

    Senate Bill to Reauthorize FDA User Fees Includes Dietary Supplement Listing Provision

    FDA Warns About Steroids or Steroid-Like Substances in Bodybuilding Supplements

    Nootropics and Adaptogens Respond to Demand for Mind and Mood Support
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain

    FDA Warns About Steroids or Steroid-Like Substances in Bodybuilding Supplements

    Nootropics and Adaptogens Respond to Demand for Mind and Mood Support

    Experts Debate Role of Supplements in Improving Public Health in EU

    GNC Adds Products from The Honest Company, Hers, and Womaness
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    Nutrition21, LLC

    Atlantia Clinical Trials

    Aiya America, Inc. (Aiya Matcha)

    Ecuadorian Rainforest

    KLK OLEO
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    Nutrition21, LLC

    Atlantia Clinical Trials

    Aiya America, Inc. (Aiya Matcha)

    Ecuadorian Rainforest

    KLK OLEO
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Breaking News

    Curcuminoid Complex Study Evidences Benefits to Gut Health and Mood

    While no gut microbiome changes were recorded, Curcugen supplementation improved measures of GI discomfort and an improved mood.

    Curcuminoid Complex Study Evidences Benefits to Gut Health and Mood
    Related CONTENT
    • Bioiberica Unveils DAOgest and Dermial at Vitafoods 2022
    • Bioiberica
    • Bioiberica Forays into Two New Health Areas
    • MilliporeSigma Launches Culture Media System for Microbiological Food Testing
    • Digestive, Gut Health Solutions Offer Downstream Benefits
    Mike Montemarano, Associate Editor 02.18.21
    A new clinical trial published in the journal BMC Complementary Medicine and Therapies has provided preliminary evidence that a curcuminoid complex known as Curcugen may have beneficial effects on digestive health, as well as mood, despite there being no significant changes in the makeup of participants’ gut microbes. The authors of the study proposed that the botanical was able to ameliorate gut health and intestinal barrier function due to previously-established inflammation-modulating activities of curcumin.
     
    The study involved 78 participants who were experiencing self-reported digestive issues – patients were randomized to take either a placebo or 500 mg of Curcugen, DolCas’ patented oleoresin-based 50% curcuminoids extract. Outcome measures included the Gastrointestinal Symptom Rating Scale, intestinal microbial profile, and assessment on the Depression, Anxiety, and Stress scale. The GSRS subset of categories evaluated gastrointestinal clusters of reflux, abdominal pain, indigestion, diarrhea, and constipation.
     
    Furthermore, investigations into the underlying mechanisms of the GI discomfort and bioactive properties were conducted at baseline and at the end of the study. SIBO (small intestinal bacterial overgrowth) was assessed via contrasting measurements of CO2, hydrogen, and methane in breath samples, while lower bowel bacterial changes were gauged with the use of at-home stool sample collections.
     
    While no significant changes in the bacterial makeup were noted between the intervention and control group, curcumin consumption was associated with a significantly greater improvement in GSRS total scores compared to placebo, as was the subsequent improvement in mood dysregulation, the authors of the study said. The results showed that there was an average of 28% reduction in the digestive symptoms of the Curcugen group, compared with 18% in the control group, and a 52% reduction in anxiety levels in the Curcugen group compared to a 16% reduction in the control group.
     
    “According to scientific literature, negative life events, stress, and anxiety are known triggers for, and exacerbators of, functional gut disorders, such as Irritable Bowel Syndrome and Functional Dyspepsia,” Dr. Shavon Jackson-Michel, Director of Medical & Scientific Affairs at DolCas Biotech, LLC, said. “The findings of this study on Curcugen offer an interesting, botanical solution to dealing comprehensively with a potential causal link between these two factors.”
     
    Gut-Brain Axis? 
     
    While there were no significant changes in the bacterial makeup of the participants’ gut microbiota, lead investigator A.L. Lopresti said that the results suggest curcumin could influence neurotransmitter activity through avenues not related to probiotic bacteria.
     
    “Results from this study indicate that changes in intestinal bacteria were not responsible for its positive gut action,” he said. “Further research using larger samples and testing methods, and applying more detailed microbial analyses might be warranted. Nevertheless, there are other potential mechanisms at play which are associated with curcumin’s GI supporting effects. These could include its influence on intestinal barrierintegrity, inflammation which influence neurotransmitter activity and visceral sensitivity.”
     
    The proprietary curcumin formulation used in the study is a uniquely derived extract sourced from the oleoresin of turmeric. Its composition contrasts significantly to the highly concentrated extract of turmeric, which has a typical concentration of 95% in most products.
     
    Instead of purifying the curcuminoids, Curcugen was composed so that it does not exclude other bioactive compounds native to the spice. Curcugen has a 98.5% turmeric profile, making it devoid of many of the dispersing agents, bioenhancers, excipients, or other materials commonly used in the industry to optimize the utility of the botanical’s highly-bioactive curcuminoids.
     
    “The beneficial role of curcumin and many of its co-actives, including turmeric essential oils and polysaccharides, has been described in research and additionally observed to work in complement with other curcuminoids when formulated together,” Shavon-Michel said. “Curcugen’s revolutionary preparation delivers turmeric’s full-spectrum benefits while facilitating enhanced bioavailability.”
     
     
    Related Searches
    • Natural/Organic
    • Herbs & Botanicals
    • Mood Health & Sleep
    • World Markets
    Related Knowledge Center
    • Digestive Health
    • Natural/Organic
    • Inflammation
    Suggested For You
    Bioiberica Unveils DAOgest and Dermial at Vitafoods 2022 Bioiberica Unveils DAOgest and Dermial at Vitafoods 2022
    Bioiberica Bioiberica
    Bioiberica Forays into Two New Health Areas Bioiberica Forays into Two New Health Areas
    MilliporeSigma Launches Culture Media System for Microbiological Food Testing MilliporeSigma Launches Culture Media System for Microbiological Food Testing
    Leveling Out the Energy Segment for Mainstream, and Rethinking Caffeine Leveling Out the Energy Segment for Mainstream, and Rethinking Caffeine
    Digestive, Gut Health Solutions Offer Downstream Benefits Digestive, Gut Health Solutions Offer Downstream Benefits
    Blue California: Delivering Sustainable, Evidence-Based Solutions for a Healthy Mind and Body Blue California: Delivering Sustainable, Evidence-Based Solutions for a Healthy Mind and Body
    ISO Certification for Charlotte ISO Certification for Charlotte's Web In-House Testing Validates Trust, Accountability
    Survey Highlights Demand for Recognizable, Health-Promoting Pet Food Ingredients Survey Highlights Demand for Recognizable, Health-Promoting Pet Food Ingredients
    TruBiotics Launches Sugar-Free Probiotic Gummies TruBiotics Launches Sugar-Free Probiotic Gummies
    Ethan Leonard Joins PanTheryx as Senior Vice President of Early Life Nutrition Ethan Leonard Joins PanTheryx as Senior Vice President of Early Life Nutrition
    FrieslandCampina Ingredients to Debut Protein Product at Food Ingredients Europe 2021 FrieslandCampina Ingredients to Debut Protein Product at Food Ingredients Europe 2021
    Foodarom Group Inc. Foodarom Group Inc.
    Dyna-Tabs, LLC Dyna-Tabs, LLC
    PanTheryx Releases New Bovine Colostrum Product, ColostrumOne Extra Strength PanTheryx Releases New Bovine Colostrum Product, ColostrumOne Extra Strength

    Related Content

    • Bioiberica Unveils DAOgest and Dermial at Vitafoods 2022

      Bioiberica Unveils DAOgest and Dermial at Vitafoods 2022

      DAOgest shown to improve histamine digestion while Dermial combines hyaluronic acid, glycosaminoglycans, and hydrolysed collagen.
      05.12.22

    • Bioiberica

      Bioiberica

      Bioiberica will be entering into two new health areas – digestive health and skin and beauty – at Vitafoods Europe 2022. Visit us at Booth; F130!
      05.05.22

    • Digestive Health | Skin Health
      Bioiberica Forays into Two New Health Areas

      Bioiberica Forays into Two New Health Areas

      The company will introduce new ingredients and its foray into digestive health and skin/beauty.
      05.03.22


    • Breaking News | Contract Manufacturing | Industry & Market News | Quality & Safety | Testing
      MilliporeSigma Launches Culture Media System for Microbiological Food Testing

      MilliporeSigma Launches Culture Media System for Microbiological Food Testing

      The new system eliminates five time-consuming steps from the standard testing process through automation.
      04.21.22

    • Cardiovascular Health | Dietary Supplements | Digestive Health | Herbs & Botanicals | Minerals | Probiotics & Prebiotics
      Digestive, Gut Health Solutions Offer Downstream Benefits

      Digestive, Gut Health Solutions Offer Downstream Benefits

      Unique ingredients and understanding of their mechanisms can help formulators deliver products that address numerous pain points.
      By Sean Moloughney, Editor 04.14.22

      Trending
      • Vitamin D3, Omega-3s, Exercise May Cumulatively Reduce Cancer Risk In Older Adults | Nutraceuticals World
      • Leaven Essential To Launch Branded Botanical Extracts To Global Markets | Nutraceuticals World
      • Indena’s Meriva Curcumin Supplement May Benefit Kidney Function
      • Vitamin D3, Omega-3s, Exercise May Cumulatively Reduce Cancer Risk in Older Adults
      • Test On Hydrolyzed Collagen Shows Resoundingly High Bioavailability | Nutraceuticals World
      Breaking News
      • Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain
      • Jordan Process Receives Nutrasource ICAP Certification for CBD
      • FDA Warns About Steroids or Steroid-Like Substances in Bodybuilding Supplements
      • Nootropics and Adaptogens Respond to Demand for Mind and Mood Support
      • Sabinsa Honors 70th Anniversary of Diplomacy Between India and Japan
      View Breaking News >
      CURRENT ISSUE

      May 2022

      • Aging in Place: Lifestyle Supplements Science-Based Solutions
      • Getting an Edge in Esports: Meeting Health & Nutrition Needs
      • Nutraceuticals for Men: Muscle Health and Performance Nutrition

      Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
      You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

      • About Us
      • Privacy Policy
      • Terms And Conditions
      • Contact Us

      follow us

      Subscribe
      Nutraceuticals World

      Latest Breaking News From Nutraceuticals World

      Bilberon Bilberry Extract Receives U.S. Patent For Eye Strain, Neck/Shoulder Pain
      Jordan Process Receives Nutrasource ICAP Certification for CBD
      FDA Warns About Steroids or Steroid-Like Substances in Bodybuilding Supplements
      Coatings World

      Latest Breaking News From Coatings World

      Award for Sustainability: Evonik Receives EcoVadis Platinum Rating Again
      HMG Paints Gets Their Running Shoes On
      AGM Secures Exclusive Distribution Agreement with Indian Partner Imkemex
      Medical Product Outsourcing

      Latest Breaking News From Medical Product Outsourcing

      Robocath Presents Results from R-Evolution Clinical Study
      Medtronic's Resolute Onyx Drug-Eluting Stent Shows Success for Left Main PCI
      Medtronic Shares 3-Year Renal Denervation Blood Pressure Trial Data
      Contract Pharma

      Latest Breaking News From Contract Pharma

      Emergent CDMO Case Studies: Project Design & Implementation of Fill/Finish Technologies
      Aptar Pharma Launches HeroTracker Sense
      MasterControl Features Quality Management and Manufacturing Execution Systems
      Beauty Packaging

      Latest Breaking News From Beauty Packaging

      Mielle Organics Welcomes Steve Pamon to Advisory Board
      Makeup Revolution Expands into Walgreens
      Nu Skin Joins EcoBeautyScore Consortium
      Happi

      Latest Breaking News From Happi

      Revolution Beauty Expands Makeup Revolution Into Walgreens
      Barentz Develops Electronic Personal Care Product Guide
      P&G Temporarily Closes Downtown Cincinnati Office Due to Potential Security Concerns
      Ink World

      Latest Breaking News From Ink World

      Award for Sustainability: Evonik Receives Platinum Rating Again
      Nazdar Ink Technologies to Showcase Latest Ink Innovations at FESPA Global Print Expo 2022
      Epson Introduces First Direct-to-Fabric Printer for North America
      Label & Narrow Web

      Latest Breaking News From Label & Narrow Web

      In-Mold Decorating Association announces 2022 IMDA Awards Competition
      Essentra Packaging invests in Landa Nanographic press
      Nazdar to manufacture VFP electronic ink for US Market
      Nonwovens Industry

      Latest Breaking News From Nonwovens Industry

      'Right' Hygiene Conference to be Held in June
      Freudenberg to Present Battery Pack and Liquid Absorbers at Battery Show
      H&V Appoints Vice President and General Counsel
      Orthopedic Design & Technology

      Latest Breaking News From Orthopedic Design & Technology

      Envista To Acquire Osteogenics
      Exactech Earns Breakthrough Status for JointMedica's Polymotion Hip Resurfacing
      Orthotic Brace Suppliers Convicted in $6.5M Fraud Scheme
      Printed Electronics Now

      Latest Breaking News From Printed Electronics Now

      Tageos Launches EOS-840 RAIN RFID Sensor Inlays
      Emerson Earns Third Consecutive 2022 ENERGY STAR Partner of the Year Award
      First Solar to Sell Japan Project Development, O&M Platforms to PAG Real Assets

      Copyright © 2022 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

      AD BLOCKER DETECTED

      Our website is made possible by displaying online advertisements to our visitors.
      Please consider supporting us by disabling your ad blocker.


      FREE SUBSCRIPTION Already a subscriber? Login