01.12.21
DuPont Nutrition and Biosciences has launched HOWARU Calm, a probiotic formulated to benefit the psychological response to perceived stress. Some 65% of adults worldwide indicate that stress is a regular part of their daily lives, according to research cited by DuPont, with prolonged stress attributable to mood, sleep, and digestive issues.
“Too much stress, or daily chronic stress has become more prevalent in today’s society and can seriously impact our mental and physical well-being and overall health,” Dr. Elaine Patterson, senior R&D scientist at DuPont, said. “Over the last few years, we have been investigating the links between the gut microbiota and brain health – the so-called microbiota-gut-brain axis. During these investigations, our focus was on discovering a natural probiotic solution targeting brain health, more specifically mood, stress, and anxiety. We are proud to finally share the fruits of our innovation and have developed a product that helps consumers target stress at the source so they can prioritize both their mental and physical health.”
The product’s featured strain, L. paracasei Lpc-37, was tested in human clinical trials to ensure its quality, efficacy, and performance. During a recent study, participants took Lpc-37 daily for five weeks before undergoing the Trier Social Stress Test, which is considered the most valid and reliable laboratory protocol for inducing stress in humans in a clinical setting. Researchers measured participants’ mood, stress, and anxiety levels in response to the five-week intervention with Lpc-37 along with their overall mood, health, and well-being throughout the study, and compared those results to a placebo group. They found that those participants taking Lpc-37 reported a significant reduction in perceived stress following five weeks of intervention.
“In the last five years, the industry has seen a 34% global increase of new probiotic supplements that help stabilize mood and combat stress, as consumers have begun to recognize the critical impact the gut has on the brain,” Stephanie Udell, global marketing leader at DuPont said. “By launching HOWARU Calm, we’re allowing dietary supplement manufacturers to develop an efficacious end-product that satisfies market demand for probiotic supplements aimed at reducing stress and promoting well-being.”
HOWARU Calm can be added to existing dietary supplement products, or used to create new ones, the company said. It can also be formulated into food and beverage products, in line with increasing consumer demand for alternative probiotic delivery formats.
“Too much stress, or daily chronic stress has become more prevalent in today’s society and can seriously impact our mental and physical well-being and overall health,” Dr. Elaine Patterson, senior R&D scientist at DuPont, said. “Over the last few years, we have been investigating the links between the gut microbiota and brain health – the so-called microbiota-gut-brain axis. During these investigations, our focus was on discovering a natural probiotic solution targeting brain health, more specifically mood, stress, and anxiety. We are proud to finally share the fruits of our innovation and have developed a product that helps consumers target stress at the source so they can prioritize both their mental and physical health.”
The product’s featured strain, L. paracasei Lpc-37, was tested in human clinical trials to ensure its quality, efficacy, and performance. During a recent study, participants took Lpc-37 daily for five weeks before undergoing the Trier Social Stress Test, which is considered the most valid and reliable laboratory protocol for inducing stress in humans in a clinical setting. Researchers measured participants’ mood, stress, and anxiety levels in response to the five-week intervention with Lpc-37 along with their overall mood, health, and well-being throughout the study, and compared those results to a placebo group. They found that those participants taking Lpc-37 reported a significant reduction in perceived stress following five weeks of intervention.
“In the last five years, the industry has seen a 34% global increase of new probiotic supplements that help stabilize mood and combat stress, as consumers have begun to recognize the critical impact the gut has on the brain,” Stephanie Udell, global marketing leader at DuPont said. “By launching HOWARU Calm, we’re allowing dietary supplement manufacturers to develop an efficacious end-product that satisfies market demand for probiotic supplements aimed at reducing stress and promoting well-being.”
HOWARU Calm can be added to existing dietary supplement products, or used to create new ones, the company said. It can also be formulated into food and beverage products, in line with increasing consumer demand for alternative probiotic delivery formats.
