03.31.20
Palmitolethanolamide (PEA), an endogenous fatty acid amide, which binds to nuclear receptors in the endocannabinoid system and is believed to naturally improve the body’s acute and chronic inflammatory and/or pain response in a dose-dependent way, either through its activities with the endocannabinoid system or through other activities which reduce inflammation. It naturally occurs in a number of foods such as soy lecithin, soybeans, egg yolk, peanuts, and alfalfa.
According to a recent human clinical trial published in the open-source journal Nutrients, Gencor’s PEA extract, called Levagen+, was effective in participant’s recovery from muscle-damaging exercise.
“WE are thrilled with the results of this study which further verifies the potent effects of Levagen+ and validates PEA’s ability to help with muscle recovery,” Chase Shryoc, Gencor’s vice president of sales and business development, said. “This study allows us to further expand our product claims into the sports nutrition market place.
The double-blind, randomized, placebo-controlled study consisted of 28 healthy males who consumed either Levagen+ PEA or a placebo pre-exercise and post-exercise on day one and then 24-48 hours post, with a blood draw at the 3-hour mark. The participants performed four sets of leg presses at 80% of one repetition maximum followed by a performance set. Researchers measured muscle soreness, thigh circumference, blood lactate concentration, biomarkers of muscle damage and inflammation, and transcription factor pathways at 1, 2, 3, 24, 48, and 72 hours post-exercise.
Levagen+ was able to reduce myoglobin, a biomarker of skeletal muscle damage, and increase protein kinase B phosphorylation following exercise. These signs suggest that PEA supplementation can aid in muscle recovery from repeat bouts of exercise by reducing the concentration of these two biomarkers.
“This clinical shows us that Levagen+ may allow individuals to exercise at a higher intensity for longer, Maggie McNamara, Gencor marketing manager, said. “Levagen+ is for the consumer looking to take their workouts to the next level, and due to Levagen+’s versatility, it can be applied in tablets, capsules, and functional foods and beverages, including ready-to-drink, sachets, smoothies, chocolate, and more.”
According to a recent human clinical trial published in the open-source journal Nutrients, Gencor’s PEA extract, called Levagen+, was effective in participant’s recovery from muscle-damaging exercise.
“WE are thrilled with the results of this study which further verifies the potent effects of Levagen+ and validates PEA’s ability to help with muscle recovery,” Chase Shryoc, Gencor’s vice president of sales and business development, said. “This study allows us to further expand our product claims into the sports nutrition market place.
The double-blind, randomized, placebo-controlled study consisted of 28 healthy males who consumed either Levagen+ PEA or a placebo pre-exercise and post-exercise on day one and then 24-48 hours post, with a blood draw at the 3-hour mark. The participants performed four sets of leg presses at 80% of one repetition maximum followed by a performance set. Researchers measured muscle soreness, thigh circumference, blood lactate concentration, biomarkers of muscle damage and inflammation, and transcription factor pathways at 1, 2, 3, 24, 48, and 72 hours post-exercise.
Levagen+ was able to reduce myoglobin, a biomarker of skeletal muscle damage, and increase protein kinase B phosphorylation following exercise. These signs suggest that PEA supplementation can aid in muscle recovery from repeat bouts of exercise by reducing the concentration of these two biomarkers.
“This clinical shows us that Levagen+ may allow individuals to exercise at a higher intensity for longer, Maggie McNamara, Gencor marketing manager, said. “Levagen+ is for the consumer looking to take their workouts to the next level, and due to Levagen+’s versatility, it can be applied in tablets, capsules, and functional foods and beverages, including ready-to-drink, sachets, smoothies, chocolate, and more.”
