Mike Montemarano, Associate Editor 06.04.21
HP Ingredients recently announced that its botanical supplement LJ100, a branded extract of the herb Eurycoma longifolia, also known as Tongkat Ali, is able to preserve normal reproductive hormonal production and interaction in young males, following previous research which demonstrated its efficacy in older adult male populations.
In the newly-published study, published in the journal Andrologia, researchers sought to discern if the ingredient would have similar effects in young males who are typically at their peak of testosterone production. In a placebo-controlled, double-blind study, 32 young men with an average age of 24.4 years consumed either 600 mg of LJ100 or a placebo daily for two weeks.
According to blood analyses of the participants, there were significant interactions involved with the LJ100 and time effects for testosterone, free testosterone, and estradiol, which were more favorable in the treatment group. Luteinizing hormone, follicle-stimulating hormone, and sexual hormone-binding globulin levels had no significant differences across the two groups.
The primary findings of the study were that LJ100 was able to increase testosterone even in healthy young men when consumed in high doses – the treatment group saw a 14% increase in testosterone, and a 34% increase in free testosterone after two weeks, while the placebo group saw no significant changes.
“The lack of changes in luteinizing hormone and follicle-stimulating hormone levels suggests that a lesser role played by Eurycoma longifolia in activating the hypothalamic-pituitary-gonadal axis in the young adults,” the authors of the study wrote. “The raised testosterone level may be due to a greater rate of hormone production via the hypothalamic-pituitary-adrenal axis. Supplementation of Eurycoma longifolia for two weeks demonstrates steroidogenic effects on young men were dose-related. Consequently, the raised testosterone following Eurycoma longifolia supplementations could benefit muscle and strength gain in young adults.”
“This study is significant in that it is the first to measure hormonal effects in healthy young men,” Annie Eng, CEO of HP Ingredients, said. “This study may certainly be used as a strong platform for formulating sports supplements for competitive athletes and trainers.”
Mike Montemarano has been the Associate Editor of Nutraceuticals World since February 2020. He can be reached at mmontemarano@rodmanmedia.com.
In the newly-published study, published in the journal Andrologia, researchers sought to discern if the ingredient would have similar effects in young males who are typically at their peak of testosterone production. In a placebo-controlled, double-blind study, 32 young men with an average age of 24.4 years consumed either 600 mg of LJ100 or a placebo daily for two weeks.
According to blood analyses of the participants, there were significant interactions involved with the LJ100 and time effects for testosterone, free testosterone, and estradiol, which were more favorable in the treatment group. Luteinizing hormone, follicle-stimulating hormone, and sexual hormone-binding globulin levels had no significant differences across the two groups.
The primary findings of the study were that LJ100 was able to increase testosterone even in healthy young men when consumed in high doses – the treatment group saw a 14% increase in testosterone, and a 34% increase in free testosterone after two weeks, while the placebo group saw no significant changes.
“The lack of changes in luteinizing hormone and follicle-stimulating hormone levels suggests that a lesser role played by Eurycoma longifolia in activating the hypothalamic-pituitary-gonadal axis in the young adults,” the authors of the study wrote. “The raised testosterone level may be due to a greater rate of hormone production via the hypothalamic-pituitary-adrenal axis. Supplementation of Eurycoma longifolia for two weeks demonstrates steroidogenic effects on young men were dose-related. Consequently, the raised testosterone following Eurycoma longifolia supplementations could benefit muscle and strength gain in young adults.”
“This study is significant in that it is the first to measure hormonal effects in healthy young men,” Annie Eng, CEO of HP Ingredients, said. “This study may certainly be used as a strong platform for formulating sports supplements for competitive athletes and trainers.”
Mike Montemarano has been the Associate Editor of Nutraceuticals World since February 2020. He can be reached at mmontemarano@rodmanmedia.com.
