04.01.03
Indication: Preeclampsia
Source: Am J Obst Gyn, 2002;187:777-784.
Research: In this study, researchers analyzed changes in biochemical markers of preeclampsia, which doctors use to assess risk in pregnant women. These markers included blood levels of vitamins E and C, a marker of free radical activity, and levels of plasminogen activator inhibitor PAI-1 and PAI-2. Researchers studied 81 at-risk women taking placebos, 79 at-risk women taking 1000 mg of vitamin C and 400 IU of vitamin E per day and 32 low risk women not taking any supplements.
Results: Levels of vitamin C were low in women at risk for preeclampsia, but they increased after supplementation. Although vitamin E levels were about the same among all women at study entry, vitamin E levels were higher in the supplemented high risk group and levels of free radical activity were reduced. Women at risk for preeclampsia had a high PAI-1 to PAI-2 ratio, but antioxidant supplements raised PAI-2 levels and improved the ratio.
Source: Am J Obst Gyn, 2002;187:777-784.
Research: In this study, researchers analyzed changes in biochemical markers of preeclampsia, which doctors use to assess risk in pregnant women. These markers included blood levels of vitamins E and C, a marker of free radical activity, and levels of plasminogen activator inhibitor PAI-1 and PAI-2. Researchers studied 81 at-risk women taking placebos, 79 at-risk women taking 1000 mg of vitamin C and 400 IU of vitamin E per day and 32 low risk women not taking any supplements.
Results: Levels of vitamin C were low in women at risk for preeclampsia, but they increased after supplementation. Although vitamin E levels were about the same among all women at study entry, vitamin E levels were higher in the supplemented high risk group and levels of free radical activity were reduced. Women at risk for preeclampsia had a high PAI-1 to PAI-2 ratio, but antioxidant supplements raised PAI-2 levels and improved the ratio.