03.01.02
Indication: Ischemic stroke
Source: JAMA 2002;288:3130-3136.
Research: A total of 43,671 men aged 40-75 years completed a detailed and validated food frequency questionnaire and were free from cardiovascular disease at baseline in 1986. The researchers determined the relative risk (RR) of stroke by subtype based on the cumulative average fish consumption or long chain omega 3 fatty acid intake, ascertained in 1986, 1990, 1994.
Results: In this study, a total of 608 participants developed stroke during the 12 year follow-up. Among these cases, 377 were confirmed as ischemic stroke, 106 were identified as hemorrhagic stroke, and the remainder could not be classified from the available medical documentation. Even a small amount of fish consumption (1-3 times per month) was associated with a significant reduction of 43% in risk of ischemic stroke, and no further benefit was observed with higher levels of fish intake. The RR for those who ate fish five or more times per week was 46% lower. Men who consumed fish at least once per month had a 44% lower risk of ischemic stroke compared with those who ate fish less than once per month. Risk of hemorrhagic stroke was not significantly associated with fish intake.
Source: JAMA 2002;288:3130-3136.
Research: A total of 43,671 men aged 40-75 years completed a detailed and validated food frequency questionnaire and were free from cardiovascular disease at baseline in 1986. The researchers determined the relative risk (RR) of stroke by subtype based on the cumulative average fish consumption or long chain omega 3 fatty acid intake, ascertained in 1986, 1990, 1994.
Results: In this study, a total of 608 participants developed stroke during the 12 year follow-up. Among these cases, 377 were confirmed as ischemic stroke, 106 were identified as hemorrhagic stroke, and the remainder could not be classified from the available medical documentation. Even a small amount of fish consumption (1-3 times per month) was associated with a significant reduction of 43% in risk of ischemic stroke, and no further benefit was observed with higher levels of fish intake. The RR for those who ate fish five or more times per week was 46% lower. Men who consumed fish at least once per month had a 44% lower risk of ischemic stroke compared with those who ate fish less than once per month. Risk of hemorrhagic stroke was not significantly associated with fish intake.