In a human clinical study scientists found that AnxioFit-1, a product distributed by EuroPharma, Inc., Green Bay, WI under the Terry Naturally brand, has a significant effect on relieving anxiety within 3 days of use. AnxioFit-1 is a highly specialized extract of specific plant compounds from a single form of echinacea (angustifolia). Past research has suggested that AnxioFit-1 attaches to cannabinoid receptors in the brain to elicit a sense of calm and relaxation, without drowsiness. The study included 33 volunteers, 22 women and 11 men with an average age of 41. All experienced mild anxiety. Subjects used AnxioFit-1 for one week, and anxiety was evaluated before, during, and after using the product. A dose of two 20 mg tablets per day decreased STAI (both state and trait) scores within 3 days, an effect that remained stable for the duration of the treatment (7 days) and for the 2 weeks that followed treatment. There were no dropouts, demonstrating that the treatment was well tolerated. No adverse effects were recorded during the treatment period.