05.01.09
Indication: Dementia
Source: J Alzheimer’s Dis, January 2009;16(1):85-91.
Research: In this study, a team of Swedish and Danish researchers set out to investigate the association between coffee and/or tea consumption at midlife and dementia/ Alzheimer’s disease (AD) risk later in life. Participants of the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) study were randomly selected from the survivors of population-based cohorts previously surveyed within the North Karelia Project and the FINMONICA study in 1972, 1977, 1982 or 1987 (midlife visit). After an average follow-up of 21 years, 1409 individuals (71%) aged 65 to 79 completed the re-examination in 1998.
Results: A total of 61 cases were identified as demented (48 with AD). Coffee drinkers at midlife had lower risk of dementia and AD later in life compared with those drinking no or only little coffee adjusted for demographic, lifestyle and vascular factors, apolipoprotein E epsilon4 allele and depressive symptoms. The lowest risk (65% decreased) was found in people who drank 3-5 cups per day. Tea drinking was relatively uncommon and was not associated with dementia/AD. As a result of these findings, researchers believe coffee drinking at midlife is associated with a decreased risk of dementia/AD later in life.
Source: J Alzheimer’s Dis, January 2009;16(1):85-91.
Research: In this study, a team of Swedish and Danish researchers set out to investigate the association between coffee and/or tea consumption at midlife and dementia/ Alzheimer’s disease (AD) risk later in life. Participants of the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) study were randomly selected from the survivors of population-based cohorts previously surveyed within the North Karelia Project and the FINMONICA study in 1972, 1977, 1982 or 1987 (midlife visit). After an average follow-up of 21 years, 1409 individuals (71%) aged 65 to 79 completed the re-examination in 1998.
Results: A total of 61 cases were identified as demented (48 with AD). Coffee drinkers at midlife had lower risk of dementia and AD later in life compared with those drinking no or only little coffee adjusted for demographic, lifestyle and vascular factors, apolipoprotein E epsilon4 allele and depressive symptoms. The lowest risk (65% decreased) was found in people who drank 3-5 cups per day. Tea drinking was relatively uncommon and was not associated with dementia/AD. As a result of these findings, researchers believe coffee drinking at midlife is associated with a decreased risk of dementia/AD later in life.