10.01.07
Researchers utilizing one of the world’s largest ethnomedicinal plant libraries recently developed two highly potent flavonoid formulas proven to convey topical anti-inflammatory effects. The botanicals, a catechin derived from the catechu tree and baicalin extracted from Chinese skullcap, were combined in two different formula ratios and then evaluated for anti-inflammatory and antioxidant effects. The formulas are the final result of screening through the PhytoLogix library at Unigen USA, Lacey, WA.
Utilizing PhytoLogix, researchers screened over 1230 organic plant extracts for potential COX-2 inhibition. The final catechin and baicalin formulas, UP566S and UP566U, demonstrated significant COX-1 and COX-2 inhibitory effects. In an in vitro test using human cells, UP566U was far more effective than Ibuprofen in acting as a LOX (5-lipoxygenase) pathway inhibitor. UP566 compounds also demonstrated an ability to suppress the gene expression of key pro-inflammatory cytokines—UP566S, in particular, exhibited antioxidant activity almost four times more powerful than vitamin C, based on ORAC test results.
Utilizing PhytoLogix, researchers screened over 1230 organic plant extracts for potential COX-2 inhibition. The final catechin and baicalin formulas, UP566S and UP566U, demonstrated significant COX-1 and COX-2 inhibitory effects. In an in vitro test using human cells, UP566U was far more effective than Ibuprofen in acting as a LOX (5-lipoxygenase) pathway inhibitor. UP566 compounds also demonstrated an ability to suppress the gene expression of key pro-inflammatory cytokines—UP566S, in particular, exhibited antioxidant activity almost four times more powerful than vitamin C, based on ORAC test results.