03.01.06
A study published in the February 1st edition of Obstetrics & Gynecology found a specific combination of black cohosh and St. John’s Wort to be effective in relieving certain symptoms of menopause. This fixed combination was studied in women with menopausal complaints with a pronounced psychological component. In the double-blind, randomized placebo-control study, 301 women experiencing menopausal complaints with psychological symptoms were treated with ethanolic St. John’s Wort extract and isopropanolic black cohosh extract or a matched placebo for 16 weeks. Menopausal complaints were evaluated by means of the Menopause Rating Scale mean score, and psychological complaints were evaluated using the Hamilton Depression Rating Scale sum score. Results proved that the mean Menopause Rating Scale score decreased 50% in the treatment group and almost 20% in the placebo group. The Hamilton Depression Rating Scale total score decreased 42% in the treatment group and 13% in the placebo group. According to researchers, the treatment was significantly superior to placebo in both measures. Further, there were no relevant group differences regarding adverse events, laboratory values or tolerability.