01.01.03
Indication: Bladder cancer
Source: Am J Epidemiol December, 2002;156(11):1002-10.
Research: The study authors examined the association between use of individual vitamin C and vitamin E supplements and bladder cancer mortality among 991,522 U.S. adults in the Cancer Prevention Study II (CPS-II) cohort. CPS-II participants completed a self-administered questionnaire at enrollment in 1982 and were followed regarding mortality through 1998.
Results: During follow-up, 1289 bladder cancer deaths occurred (962 in men and 327 in women). Rate ratios were adjusted for age, sex, cigarette smoking, education and consumption of citrus fruits and vegetables. Regular vitamin C supplement use was not associated with bladder cancer mortality, regardless of duration. Regular vitamin E supplement use for 10 years was associated with a reduced risk of bladder cancer mortality, but regular use of shorter duration was not. Results support the hypothesis that long-duration vitamin E supplement use may reduce the risk of bladder cancer mortality.
Source: Am J Epidemiol December, 2002;156(11):1002-10.
Research: The study authors examined the association between use of individual vitamin C and vitamin E supplements and bladder cancer mortality among 991,522 U.S. adults in the Cancer Prevention Study II (CPS-II) cohort. CPS-II participants completed a self-administered questionnaire at enrollment in 1982 and were followed regarding mortality through 1998.
Results: During follow-up, 1289 bladder cancer deaths occurred (962 in men and 327 in women). Rate ratios were adjusted for age, sex, cigarette smoking, education and consumption of citrus fruits and vegetables. Regular vitamin C supplement use was not associated with bladder cancer mortality, regardless of duration. Regular vitamin E supplement use for 10 years was associated with a reduced risk of bladder cancer mortality, but regular use of shorter duration was not. Results support the hypothesis that long-duration vitamin E supplement use may reduce the risk of bladder cancer mortality.