01.16.12
A safety manuscript for ESM Technologies’ flagship ingredient NEM (Natural Eggshell Membrane), titled “Safety evaluation of a natural eggshell membrane-derived product,” has been published in the journal Food and Chemical Toxicology. This research evaluated NEM’s safety via multiple in vitro and in vivo toxicological studies.
Studies were conducted by a variety of independent research labs. NEM was evaluated for cytotoxicity, genotoxicity and oral toxicity (both single acute dose and 90-day repeated-dose) at doses up to 50 times the clinically tested human equivalent dose. NEM did not show any signs of toxicity in any of the areas evaluated. These results demonstrate that NEM is safe for human consumption at the standard daily dose of 500 mg per day.
This safety evaluation formed the basis for an independent expert panel to deem NEM Generally Recognized As Safe (GRAS), allowing NEM to expand into the food and beverage industry. There are numerous food and beverage categories for which NEM is approved for use; a few include beverages and beverage bases, fruit and vegetable juices, baked goods, soft candy and snack foods. The Allowable Daily Intake (ADI) for NEM is up to 14 grams per day for food use and intake. For further information: www.esmingredients.com
Studies were conducted by a variety of independent research labs. NEM was evaluated for cytotoxicity, genotoxicity and oral toxicity (both single acute dose and 90-day repeated-dose) at doses up to 50 times the clinically tested human equivalent dose. NEM did not show any signs of toxicity in any of the areas evaluated. These results demonstrate that NEM is safe for human consumption at the standard daily dose of 500 mg per day.
This safety evaluation formed the basis for an independent expert panel to deem NEM Generally Recognized As Safe (GRAS), allowing NEM to expand into the food and beverage industry. There are numerous food and beverage categories for which NEM is approved for use; a few include beverages and beverage bases, fruit and vegetable juices, baked goods, soft candy and snack foods. The Allowable Daily Intake (ADI) for NEM is up to 14 grams per day for food use and intake. For further information: www.esmingredients.com