09.01.08
Indication: Age-related macular degeneration (AMD)
Source: Arch Ophthalmol, June 2008;126(6):826-33.
Research: Researchers systematically reviewed the evidence on dietary omega 3 fatty acid and fish intake in the primary prevention of age-related macular degeneration (AMD). Seven databases were systematically searched with no limits on publication year or language using standardized criteria. Randomized, controlled trials and prospective cohort, case-control, and cross-sectional studies were included. Of 2754 abstracts identified, 3 prospective cohort, 3 case-control, and 3 cross-sectional studies met the criteria.
Results: These 9 studies provided data on a total sample of 88,974 people, including 3203 AMD cases. A high dietary intake of omega 3 fatty acids was associated with a 38% reduction in the risk of late AMD. Fish intake at least twice a week was also associated with a reduced risk of both early AMD and late AMD. Although this meta-analysis suggests that consumption of fish and foods rich in omega 3s may be associated with a lower risk of AMD, researchers still believe there is insufficient evidence from the current literature—with few prospective studies and no randomized clinical trials—to support their routine consumption for AMD prevention.
Source: Arch Ophthalmol, June 2008;126(6):826-33.
Research: Researchers systematically reviewed the evidence on dietary omega 3 fatty acid and fish intake in the primary prevention of age-related macular degeneration (AMD). Seven databases were systematically searched with no limits on publication year or language using standardized criteria. Randomized, controlled trials and prospective cohort, case-control, and cross-sectional studies were included. Of 2754 abstracts identified, 3 prospective cohort, 3 case-control, and 3 cross-sectional studies met the criteria.
Results: These 9 studies provided data on a total sample of 88,974 people, including 3203 AMD cases. A high dietary intake of omega 3 fatty acids was associated with a 38% reduction in the risk of late AMD. Fish intake at least twice a week was also associated with a reduced risk of both early AMD and late AMD. Although this meta-analysis suggests that consumption of fish and foods rich in omega 3s may be associated with a lower risk of AMD, researchers still believe there is insufficient evidence from the current literature—with few prospective studies and no randomized clinical trials—to support their routine consumption for AMD prevention.