• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    Nutraceuticals for Men: Muscle Health and Performance Nutrition

    Aging in Place: Healthy Lifestyles Supplement Science-Based Solutions

    Getting an Edge in Esports: Meeting the Health Needs of Competitive Gamers

    Beyond CBD: Cannabis Compounds Warrant Recognition and More Research

    Leveling Out the Energy Segment for Mainstream, and Rethinking Caffeine
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    Thorne Relaunches Gut Health Test with Microbiome Wipe

    Alkemist Labs Announces Alkemist Assured Seal and Next Generation Transparency Reports

    GC Rieber Foundations Expand Philanthropic Efforts

    Danone Celebrates 10th anniversary of Grant Program for Probiotics Research

    Stratum Nutrition’s Patent Portfolio Grows to Europe and Canada
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    GC Rieber Foundations Expand Philanthropic Efforts

    Danone Celebrates 10th anniversary of Grant Program for Probiotics Research

    Botanical Ingredient MorActive Evidenced to Relieve Back Discomfort

    Cargill’s Stevia Sustainability Program Benchmarked by FSA

    GOED Creates Infographic Highlighting Omega-3 Health Claims Approved in Europe
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    Thorne Relaunches Gut Health Test with Microbiome Wipe

    Alkemist Labs Announces Alkemist Assured Seal and Next Generation Transparency Reports

    GC Rieber Foundations Expand Philanthropic Efforts

    Danone Celebrates 10th anniversary of Grant Program for Probiotics Research

    Stratum Nutrition’s Patent Portfolio Grows to Europe and Canada
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    Thorne Relaunches Gut Health Test with Microbiome Wipe

    Danone Celebrates 10th anniversary of Grant Program for Probiotics Research

    Beyond Raw Launches Concept X Pre-Workout Line

    Botanical Ingredient MorActive Evidenced to Relieve Back Discomfort

    Kyowa Hakko Appoints Dr. Colin Hill to Immuse Scientific Advisory Board
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    Xsto Solutions

    ESHA Research

    Gencor

    Ecuadorian Rainforest

    Aiya America, Inc. (Aiya Matcha)
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    Xsto Solutions

    ESHA Research

    Gencor

    Ecuadorian Rainforest

    Aiya America, Inc. (Aiya Matcha)
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Online Exclusives

    GOED Publishes Fish Oil Oxidation Analysis

    The study analyzed changes in the chemical composition of fish oil exposed to over-oxidating conditions.

    GOED Publishes Fish Oil Oxidation Analysis
    The study identified additional oxidative products that formulators should be on the lookout for, despite the unlikelihood that they will be present.
    Related CONTENT
    • Alkemist Labs Announces Alkemist Assured Seal and Next Generation Transparency Reports
    • Danone Celebrates 10th anniversary of Grant Program for Probiotics Research
    • Botanical Ingredient MorActive Evidenced to Relieve Back Discomfort
    • Cargill’s Stevia Sustainability Program Benchmarked by FSA
    • FDA Issues Draft Guidance on NDI Enforcement Discretion
    By Mike Montemarano, Associate Editor10.30.20
    Formulators working with fish oil should have comprehensive knowledge of oxidation and its effects on the specific omega-3 product being produced. A recent study demonstrated that plenty of variables are at play that affect quality and safety.
     
    In a recent analysis published by the Global Organization for EPA and DHA Omega-3s (GOED) in the journal Foods, researchers analyzed the chemical composition of fish oil after exposure to varied oxidative conditions.
     
    Omega-3s of all kinds are prone to oxidative degradation. Without appropriate preventive measures, oxidation can cause fish oil products to exceed voluntary safety recommendations.
     
    Additionally, a number of academic publications have claimed that fish oil supplements were mostly oxidized, did not contain the claimed amount of EPA or DHA, and could be associated with negative health consequences.
     
    To reach an understanding about the changes to fish oil’s chemical composition over time, several collaborating GOED members teamed up with academic researcher from Belgium, France, and the University of California, Davis.
     
    The study is part of GOED’s Oxidation Plan, which involves a number of clinical trials intended to address oxidation-related complaints, such as that oxidation reduces EPA/DHA levels and could create a number of harmful compounds, among other complaints.
     
    Previous Research
    The GOED study was carried out in response to a previously-published study which appeared in the American Journal of Physiology in 2016 called “Oxidized fish oil in rat pregnancy causes high newborn mortality and increases maternal insulin resistance.”
     
    During that study, pregnant rats were administered 1 ml of either unoxidized or highly oxidized hoki liver oil, or a placebo until birth. Maternal intake of oxidized fish oil significantly increased insulin resistance at the time of weaning compared to control and placebo, and the oxidized fish oil group also had significantly higher rates of infant mortality at day 2. The oxidized fish oil in the study was treated for 30 days by bubbling oxygen under a fluorescent lamp at room temperature, causing it to be characterized by a high concentration of lipid peroxides, which the authors believed could have been associated with oxidative stress (which is known to have adverse effects on a number of conditions related to pregnancy). The fish oil was not treated with antioxidants, and no co-administration of antioxidants occurred during this trial.  
     
    A Second Look
    According to the more recent publication to which GOED contributed, the adverse effect on pregnant rats caused by highly rancid hoki liver oil used in the 2016 was attributed to lipid hydroperoxides which formed during the experimental conditions to which the oil was exposed to. Other chemical changes that the authors hypothesized could have been present in the oxidized hoki liver oil at the time were not discussed.
     
    The more recent trial replicated the conditions by which the hoki liver oil was oxidized in the previous study, and exposed anchovy oil to similar conditions, as anchovies are a common source of commercially available fish oil products.
     
    Additionally, the study analyzed the effects of a less extreme oxidation method, which involved exposing fish oil to air contact in the dark, which is an oxidation condition “more relevant to retail products,” the authors said. It was determined that anchovy oil had a different chemical oxidation signature to hoki liver oil, due primarily to the fact that each contained a different profile of antioxidants, and that the applied oxidative conditions caused significant differences.
     
    Study authors said the highly rancid hoki liver oil, which was intended to replicate the oil analyzed in the 2016 study, contained potentially harmful chemicals that may have been overlooked, and that the infant mortality and insulin resistance seen in pregnant rats may have been attributed to lipid hydroperoxides while isoprostanoids and oxysterols were overlooked.
     
    “Quality guidelines for edible oils set by regulatory authorities exist to avoid rancid products entering the market,” the authors of the study said. “Producers of oils and retailers have also set voluntary quality limits through organizations such as [GOED]. Industry guidelines assist in making sure products comply with the applicable quality limits set by regulatory agencies for the markets where products are sold […] Recent studies show that the large majority of ingredient oils as well as finished products found in retail stores is of acceptable quality, although further improvements in oxidative quality can be made for some retail products.”
     
    Further, the authors discussed other studies providing evidence that consuming mildly oxidized fish oils, rather than oils which are extremely rancid, does not significantly alter biochemical parameters in the body.
     
    “The temporal analysis of chemical compositional changes of minimally refined antioxidant-free hoki liver oil under harsh oxidative conditions has confirmed the marked over-oxidation of the oil,” the authors of the study concluded. “Extension of the study to a different type of oxidation condition, as well as including a more commonly used and antioxidant-stabilized refined anchovy oil, demonstrated that different oils contain and develop distinct patterns of oxidation products, and that the presence of added antioxidants markedly delays oxidation.”
     
    The authors also concluded that other oxidation products besides fatty acid peroxides should be considered to understand how oxidation effects any fish oil product, such as those derived from oil components including other fatty acids and lipids. A conclusion cannot be drawn for all fish oil ingredients based on the results of one oxidated fish oil or product, they said.
     
    Additionally, “fish oils and other EPA/DHA omega-3 products would never be exposed to the harshness of the employed experimental oxidation conditions in this study,” the authors said. Beyond refinement and added antioxidants, encapsulation and packaging provides another parameter of oxidation resistance in omega-3 products.
     
    Related Searches
    • Quality & Safety
    • Research
    • Omega-3s
    • Antioxidants
    Related Knowledge Center
    • Antioxidants
    • Delivery & Dosage Technologies
    • Research
    Suggested For You
    Alkemist Labs Announces Alkemist Assured Seal and Next Generation Transparency Reports Alkemist Labs Announces Alkemist Assured Seal and Next Generation Transparency Reports
    Danone Celebrates 10th anniversary of Grant Program for Probiotics Research Danone Celebrates 10th anniversary of Grant Program for Probiotics Research
    Botanical Ingredient MorActive Evidenced to Relieve Back Discomfort Botanical Ingredient MorActive Evidenced to Relieve Back Discomfort
    Cargill’s Stevia Sustainability Program Benchmarked by FSA Cargill’s Stevia Sustainability Program Benchmarked by FSA
    FDA Issues Draft Guidance on NDI Enforcement Discretion FDA Issues Draft Guidance on NDI Enforcement Discretion
    GOED Creates Infographic Highlighting Omega-3 Health Claims Approved in Europe GOED Creates Infographic Highlighting Omega-3 Health Claims Approved in Europe
    Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission Expert Consensus Statement: Diet is Best Primary Intervention to Achieve Diabetes Remission
    Choline Alone May Improve Maternal DHA Status During Pregnancy Choline Alone May Improve Maternal DHA Status During Pregnancy
    Consumer Conviction: Results of consumer satisfaction study on mental wellness and sleep. Consumer Conviction: Results of consumer satisfaction study on mental wellness and sleep.
    Jordan Process Receives Nutrasource ICAP Certification for CBD Jordan Process Receives Nutrasource ICAP Certification for CBD
    Draft Senate Bill to Reauthorize FDA User Fees Includes Dietary Supplement Listing Provision Draft Senate Bill to Reauthorize FDA User Fees Includes Dietary Supplement Listing Provision
    FDA Warns About Steroids or Steroid-Like Substances in Bodybuilding Products  FDA Warns About Steroids or Steroid-Like Substances in Bodybuilding Products
    Experts Debate Role of Supplements in Improving Public Health in EU Experts Debate Role of Supplements in Improving Public Health in EU
    Solvay Invests in Suanfarma’s Vanillin Production Solvay Invests in Suanfarma’s Vanillin Production
    GNC Adds Products from The Honest Company, Hers, and Womaness GNC Adds Products from The Honest Company, Hers, and Womaness

    Related Content

    • Breaking News | Consumer Trends | Industry & Market News | Quality & Safety | Testing
      Alkemist Labs Announces Alkemist Assured Seal and Next Generation Transparency Reports

      Alkemist Labs Announces Alkemist Assured Seal and Next Generation Transparency Reports

      The new transparency program can display testing accuracy to consumers and B2B customers.
      05.24.22

    • Digestive Health | Immune Function | Probiotics & Prebiotics | Research
      Danone Celebrates 10th anniversary of Grant Program for Probiotics Research

      Danone Celebrates 10th anniversary of Grant Program for Probiotics Research

      Two graduate students were awarded $50,000 in grants from the annual gut microbiome, yogurt, and probiotics-focused program.
      05.24.22

    • Antioxidants | Breaking News | Dietary Supplements | Herbs & Botanicals | Inflammation | Research News | Supplier News
      Botanical Ingredient MorActive Evidenced to Relieve Back Discomfort

      Botanical Ingredient MorActive Evidenced to Relieve Back Discomfort

      The novel combination of moringa seed extract and Sunfiber was tested in 40 healthy adults.
      05.23.22


    • Breaking News | Certifications, Approvals & Patents | Flavors & Colors | Functional Foods & Beverages | Herbs & Botanicals
      Cargill’s Stevia Sustainability Program Benchmarked by FSA

      Cargill’s Stevia Sustainability Program Benchmarked by FSA

      The company is the first stevia producer to have its entire network achieve this third-party approval.
      05.23.22

    • Dietary Supplements | Regulations
      FDA Issues Draft Guidance on NDI Enforcement Discretion

      FDA Issues Draft Guidance on NDI Enforcement Discretion

      Amnesty for late NDI notifications is intended to encourage manufacturers and distributors to correct past failures while collecting safety data, FDA said.
      By Sean Moloughney, Editor 05.20.22

      Trending
      • Leaven Essential To Launch Branded Botanical Extracts To Global Markets | Nutraceuticals World
      • Oregon Files Lawsuit Against GNC | Nutraceuticals World
      • Coca-Cola To Phase Out Honest Tea Brand By Year’s End, Citing Supply Chain Challenges | Nutraceuticals World
      Breaking News
      • Thorne Relaunches Gut Health Test with Microbiome Wipe
      • Alkemist Labs Announces Alkemist Assured Seal and Next Generation Transparency Reports
      • GC Rieber Foundations Expand Philanthropic Efforts
      • Danone Celebrates 10th anniversary of Grant Program for Probiotics Research
      • Stratum Nutrition’s Patent Portfolio Grows to Europe and Canada
      View Breaking News >
      CURRENT ISSUE

      May 2022

      • Aging in Place: Lifestyle Supplements Science-Based Solutions
      • Getting an Edge in Esports: Meeting Health & Nutrition Needs
      • Nutraceuticals for Men: Muscle Health and Performance Nutrition

      Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
      You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

      • About Us
      • Privacy Policy
      • Terms And Conditions
      • Contact Us

      follow us

      Subscribe
      Nutraceuticals World

      Latest Breaking News From Nutraceuticals World

      Thorne Relaunches Gut Health Test with Microbiome Wipe
      Alkemist Labs Announces Alkemist Assured Seal and Next Generation Transparency Reports
      GC Rieber Foundations Expand Philanthropic Efforts
      Coatings World

      Latest Breaking News From Coatings World

      What are You Reading this Week?
      Nippon Paint Automotive Americas Appoints Robert Angart CEO and President
      Sustainability, Economy are Focus of BCF’s Annual Conference
      Medical Product Outsourcing

      Latest Breaking News From Medical Product Outsourcing

      MPO's Most-Read Stories This Week—May 28
      New Breast Implant Surgery Guidelines to Enhance Patient Safety
      Rhythm Management Group Debuts RhythmSynergy Tech Platform
      Contract Pharma

      Latest Breaking News From Contract Pharma

      iECURE Enters Agreement with Center for Breakthrough Medicines
      CPDC Enters Clinical Manufacturing Deal with CellBion
      Olon to Build New R&D Center in Italy
      Beauty Packaging

      Latest Breaking News From Beauty Packaging

      K-Beauty Brand Siita Shares Plastic Decomposition Technology with the Beauty Industry
      Shellworks Raises $6.2 Million in Seed Funding
      Ulta Beauty Reports Record First Quarter 2022 Results
      Happi

      Latest Breaking News From Happi

      Global Skincare Treatment Devices Market Expected to Grow at Over 11.5% CAGR Rate Through 2028
      Technology Cuts Plastic Decomposition from 500 Years to Three Months
      Honeywell Addresses Critical Issues Such as Sustainability, Workforce Training and Digitalization
      Ink World

      Latest Breaking News From Ink World

      Weekly Recap: Flint Group, New Inks from Siegwerk and Zeller+Gmelin Lead This Week’s News
      Orion to Finish Gas Black Expansion in Germany by Early 2023
      Richard Childress Racing Shows Off New Wraps for 2022 NASCAR Season
      Label & Narrow Web

      Latest Breaking News From Label & Narrow Web

      UPM Raflatac accelerates label growth with acquisition
      Labelexpo Asia 2022 postponed
      Teklynx software helps Top Clean Injection validate labels
      Nonwovens Industry

      Latest Breaking News From Nonwovens Industry

      Rael Raises $35M in Series B Funding
      Schobertechnologies Offers Rotary Web-fed Converting Solutions
      Thorne Relaunches Gut Health Test with Microbiome Wipe
      Orthopedic Design & Technology

      Latest Breaking News From Orthopedic Design & Technology

      ODT's Most-Read Stories This Week—May 28
      Toetal Solutions Raises $1.02 Million in New Financing
      ManaMed's ManaSport Wearable Ultrasound Earns FDA Nod
      Printed Electronics Now

      Latest Breaking News From Printed Electronics Now

      Weekly Recap: OPV’s Future, Graphene Flagship and Japan Display Top This Week’s Stories
      SEMI Foundation Receives $1.5 Million Grant to Bolster Michigan’s Semiconductor Talent Pipeline
      onsemi Recognized by Fortune 500 for Its Transformation Journey

      Copyright © 2022 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

      AD BLOCKER DETECTED

      Our website is made possible by displaying online advertisements to our visitors.
      Please consider supporting us by disabling your ad blocker.


      FREE SUBSCRIPTION Already a subscriber? Login