• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    Researchers Develop New Global Estimate of Medicinal Plant Species and Conservation Status

    All Eyes on Vision Health

    Health Benefits of Vitamin K: A Contemporary Cornerstone of Heart and Bone Health

    Vitamin D: A Fixture of Supplementation and Fortification

    Magnesium: An Essential Mineral with Many Forms and Functions
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Glossary
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    Nutrasource Rebrands Clinical Trial Site to Apex Trials

    Kerry Sponsors Upcycled Food Foundation Research Fellowship

    Probiotics Supplementation Reduces Complications in Colorectal Cancer Patients

    Vitamin D Supplementation Reduces Risk of Dynapenia

    Sustained-Release Caffeine Ingredient Offers Mood, Performance Benefits
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    Natural Products Association Blasts FDA for Punting CBD Issues to Congress

    Probiotics Supplementation Reduces Complications in Colorectal Cancer Patients

    FDA Denies CBD Petitions, Cites Safety Concerns, Looks to Congress for New Regulatory Pathway

    Vitamin D Supplementation Reduces Risk of Dynapenia

    Sustained-Release Caffeine Ingredient Offers Mood, Performance Benefits
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    Nutrasource Rebrands Clinical Trial Site to Apex Trials

    Natural Products Association Blasts FDA for Punting CBD Issues to Congress

    Kerry Sponsors Upcycled Food Foundation Research Fellowship

    Probiotics Supplementation Reduces Complications in Colorectal Cancer Patients

    FDA Denies CBD Petitions, Cites Safety Concerns, Looks to Congress for New Regulatory Pathway
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    Probiotics Supplementation Reduces Complications in Colorectal Cancer Patients

    Vitamin D Supplementation Reduces Risk of Dynapenia

    Sustained-Release Caffeine Ingredient Offers Mood, Performance Benefits

    Multi-Strain Probiotic Improves Self-Reported Mood, Sleep, Serotonin Levels

    CRN Highlights 'Supplement to Savings' Report for National Heart Month
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    Botanic Healthcare LLC

    PhytoGaia Inc

    Verdure Sciences

    JRS Pharma

    Gencor
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    Botanic Healthcare LLC

    PhytoGaia Inc

    Verdure Sciences

    JRS Pharma

    Gencor
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Breaking News

    Pre-Clinical Studies Reveal Weight Loss Mechanism of Herbal Formula

    Two pre-clinical studies and a human clinical trial shed light on the herbal combination’s ability to curb adipogenesis and increase resting energy expenditure.

    Pre-Clinical Studies Reveal Weight Loss Mechanism of Herbal Formula
    Related CONTENT
    • Probiotics Supplementation Reduces Complications in Colorectal Cancer Patients
    • Vitamin D: A Fixture of Supplementation and Fortification
    • Healthy, Clean Label Snacks and Nutrition Bars Help Fill Nutrient Gap Cleaved By Modern Lifestyles
    • Black Seed Oil and Astaxanthin Formula Linked to Fewer Respiratory Complaints, Better Mood
    • NGS Begins Pilot Trial of Sports Supplement for Children
    03.02.22
    A series of two pre-clinical studies on an herbal formulation marketed as Slendacor by PLT Health Solutions provided insights into the mechanism of action behind the ingredient’s associations with weight loss and improved body composition. Slendacor is a patented combination of the extracts of turmeric, drumstick leaves, and curry leaves.
     
    The studies, focused on energy expenditure, revealed a dual mode of action for the ingredient. It can control fat reserves through the modulation of adipogenesis and lipolysis, while also increasing energy expenditure through thermogenesis.
     
    “Our new data on lipolysis shows that Slendacor is not just breaking fat down but increasing the metabolism of that fat and changing the metabolic activity of those fat cells,” Dr. Jeremy Appleton, ND, director of medical and scientific affairs for PLT, said. “It is burning fat rather than sending it to energy reserves. Healthy weight management has never been solely about shedding pounds. As important as weight loss is to many consumers, we know that healthy and sustainable changes to body weight must involve supporting other related systems, like cardiovascular and metabolic health. These new studies help us understand Slendacor as an integral part of holistic health management program, one that includes body weight, but in the greater context of cardiometabolic health.”
     
    A human clinical study focused on a single daily dose of Slendacor and its effects on resting metabolic rate. Participants using Slendacor showed up to a 15.2% increase in resting energy expenditure (REE) on day seven. REE and calorie burning increased significantly from baseline on day one of the study. The study also measured heart rate, blood pressure, and mood. At no point during the study were there significant increases in heart rate or blood pressure in the Slendacor group, suggesting there was no stimulant activity, according to PLT Health Solutions.
     
    One of the two pre-clinical studies, appearing in Lipids in Health and Disease, relied on high-fat diet-fed animals. Observations indicated that Slendacor was able to increase resting energy expenditure through increasing carbohydrate and fat oxidation via upregulation of UCP-1, a type of protein found in brown adipose tissue which is considered thermogenic. Additionally, the ingredient also “improves the metabolic markers in serum and liver, indicative of possible protection from high-fat diet-induced fatty liver and clinical symptoms of metabolic dysfunction,” the authors concluded.
     
    The second of the two studies, also appearing in Lipids in Health and Disease, reached a similar conclusion regarding the up-regulation of UCP-1 in high-fat diet-fed rats. Further, it broke down the observed changes in adipogenic proteins seen throughout the trial, indicating that the ingredient also targets the processes of fat cell growth.
     
    These mechanism of action studies follow a human clinical study published in Diabetes, Obesity, and Metabolism which lasted for 16 weeks. During the 16-week trial, healthy overweight adults experienced consistent body weight reductions compared to a placebo group, and by the end of the experimental period, averaged a total weight loss of nearly 12 pounds, compared to no significant changes in the placebo group. Further, the Slendacor group lost two inches of waist circumference on average and had experienced no reductions in lean body mass.
     
    “Slendacor was introduced in 2017, and its fast-acting benefits, clean label formulation, and robust portfolio of scientific support helped it quickly become a market leading dietary supplement weight management ingredient around the world – powering top brands in the United States, Australia, Europe, and Brazil,” Seth Flowerman, president and CEO of PLT Health Solutions, said. “These new studies further enhance the range of claims that our customers will be able to communicate and demonstrate how Slendacor promotes overall human health while helping people manage their weight.”
    Related Searches
    • Dietary Supplements
    • Herbs & Botanicals
    • Research
    • Weight Management/Weight Loss
    Related Knowledge Center
    • Weight Management/Weight Loss
    • Research
    • Herbs & Botanicals
    Suggested For You
    Probiotics Supplementation Reduces Complications in Colorectal Cancer Patients Probiotics Supplementation Reduces Complications in Colorectal Cancer Patients
    Healthy, Clean Label Snacks and Nutrition Bars Help Fill Nutrient Gap Cleaved By Modern Lifestyles Healthy, Clean Label Snacks and Nutrition Bars Help Fill Nutrient Gap Cleaved By Modern Lifestyles
    Vitamin D: A Fixture of Supplementation and Fortification Vitamin D: A Fixture of Supplementation and Fortification
    Black Seed Oil and Astaxanthin Formula Linked to Fewer Respiratory Complaints, Better Mood Black Seed Oil and Astaxanthin Formula Linked to Fewer Respiratory Complaints, Better Mood
    NGS Begins Pilot Trial of Sports Supplement for Children NGS Begins Pilot Trial of Sports Supplement for Children
    Sirio Pharma Acquires Best Formulations Sirio Pharma Acquires Best Formulations
    Open Book Extracts and Purissima Announce Study on Cannabinoids and Menstrual Pain Open Book Extracts and Purissima Announce Study on Cannabinoids and Menstrual Pain
    Alpha-Carotene Shown to Improve Muscle Strength in Older Adults Alpha-Carotene Shown to Improve Muscle Strength in Older Adults
    Personalized Nutrition: A Steep Learning Curve for the Dietary Supplement Market Personalized Nutrition: A Steep Learning Curve for the Dietary Supplement Market
    Novozymes and Chr. Hansen Enter Merger Agreement Novozymes and Chr. Hansen Enter Merger Agreement
    Novozymes OneHealth Debuts in U.S. to Target ‘Profound’ Consumer Health Challenges Novozymes OneHealth Debuts in U.S. to Target ‘Profound’ Consumer Health Challenges
    Ethical Naturals Inc. and Nammex Launch New Mushroom-Plus Ingredient Line Ethical Naturals Inc. and Nammex Launch New Mushroom-Plus Ingredient Line
    DSM Launches Complete, Soy-Free, Gluten-Free Vegetable Protein DSM Launches Complete, Soy-Free, Gluten-Free Vegetable Protein
    Weight Loss, Muscle Building In the Crosshairs Weight Loss, Muscle Building In the Crosshairs
    PLT Launches Water-Soluble Form of Rhodiola Extract PLT Launches Water-Soluble Form of Rhodiola Extract

    Related Breaking News

    • Breaking News | Cancer Risk | Digestive Health | Medical Nutrition | Probiotics & Prebiotics | Research | Research News
      Probiotics Supplementation Reduces Complications in Colorectal Cancer Patients

      Probiotics Supplementation Reduces Complications in Colorectal Cancer Patients

      The patients, who underwent radical surgery and chemotherapy, saw significant improvements in GI complications and gut dysbiosis.
      01.26.23

    • Bone & Joint Health | Delivery & Dosage Technologies | Dietary Supplements | Immune Function | Research | Vitamins
      Vitamin D: A Fixture of Supplementation and Fortification

      Vitamin D: A Fixture of Supplementation and Fortification

      The most widely-supplemented nutrient continues to prevail in large-scale studies on immunity, healthy aging, and more.
      By Mike Montemarano, Associate Editor 01.20.23

    • Cognitive Function | Nutrition Bars & Snacks | Proteins, Peptides, Amino Acids
      Healthy, Clean Label Snacks and Nutrition Bars Help Fill Nutrient Gap Cleaved By Modern Lifestyles

      Healthy, Clean Label Snacks and Nutrition Bars Help Fill Nutrient Gap Cleaved By Modern Lifestyles

      Many consumers reach for snacks to help meet their health goals, but they want value and great flavor too.
      By Sean Moloughney, Editor 01.20.23


    • Breaking News | Herbs & Botanicals | Immune Function | Mood Health & Sleep | Research News | Sports Nutrition
      Black Seed Oil and Astaxanthin Formula Linked to Fewer Respiratory Complaints, Better Mood

      Black Seed Oil and Astaxanthin Formula Linked to Fewer Respiratory Complaints, Better Mood

      TriNutra’s Thymoquin in combination with astaxanthin oil improved these markers and microbiome balance in marathon and half-marathon runners.
      01.11.23

    • Breaking News | Dietary Supplements | Infant & Children's Health | Minerals | Proteins, Peptides, Amino Acids | Research News | Sports Nutrition | Vitamins
      NGS Begins Pilot Trial of Sports Supplement for Children

      NGS Begins Pilot Trial of Sports Supplement for Children

      The blend of essential nutrients, proteins, and amino acids will be tested in children who play soccer for effect on athletic performance.
      01.11.23

    Loading, Please Wait..
    Trending
    • NOW Switches To Bottles Made From 100% Post-Consumer Recycled Resin
    • Shiitake Mushroom Extract Appears Helpful In HPV Infections
    • The Functional Chocolate Company Launches Painfree Chocolate
    Breaking News
    • Nutrasource Rebrands Clinical Trial Site to Apex Trials
    • Kerry Sponsors Upcycled Food Foundation Research Fellowship
    • Probiotics Supplementation Reduces Complications in Colorectal Cancer Patients
    • Vitamin D Supplementation Reduces Risk of Dynapenia
    • Sustained-Release Caffeine Ingredient Offers Mood, Performance Benefits
    View Breaking News >
    CURRENT ISSUE

    Jan/Feb 2023

    • Healthy, Clean Label Snacks and Nutrition Bars Help Fill Nutrient Gap Cleaved By Modern Lifestyles
    • Magnesium: An Essential Mineral with Many Forms and Functions
    • Vitamin D: A Fixture of Supplementation and Fortification
    • Health Benefits of Vitamin K: A Contemporary Cornerstone of Heart and Bone Health
    • All Eyes on Vision Health
    • Researchers Develop New Global Estimate of Medicinal Plant Species and Conservation Status
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    Nutrasource Rebrands Clinical Trial Site to Apex Trials
    Kerry Sponsors Upcycled Food Foundation Research Fellowship
    Probiotics Supplementation Reduces Complications in Colorectal Cancer Patients
    Coatings World

    Latest Breaking News From Coatings World

    Epoxytec Announces New Website Launch
    Paints and Coatings Market Worth $212B by 2026: MarketsandMarkets
    Axalta Releases Fourth Quarter and Full Year 2022 Results
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    FDA OKs Tidepool Loop App Connecting CGMs, Insulin Pumps
    GE HealthCare, Imricor Team Up for Interventional Cardiac MRI
    Promising Study Results Released for Uncontrolled Hypertension Treatment
    Contract Pharma

    Latest Breaking News From Contract Pharma

    SK bioscience Introduces New Global Partnership Model for Vaccines
    Merck's KEYTRUDA Wins Expanded Approval in Non-Small Cell Lung Cancer
    Bone Biologics Engages Avania for NB1 Clinical Trial
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    LVMH Reports Record 2022
    Haircare Brand Uncle Funky’s Daughter Announces Retail Expansion
    TRESemmé Introduces New Pro Infusion Collection
    Happi

    Latest Breaking News From Happi

    Scott’s Liquid Gold Sells Wood and Floor Care Brands
    Ingredient Platform ClearForMe Expands into Baby Care
    Existing Regulatory Framework for Foods & Supplements Not Appropriate for CBD: FDA
    Ink World

    Latest Breaking News From Ink World

    Roland DGA Announces Major Expansion of TrueVIS Printer Family
    Neos Expands Production Capacity, European Market Presence
    Celanese Launches Nine New Conductive Inks for Consumer Applications
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Channeled Resources launches blank labels with PET liner
    Infigo partners with Four Pees in Benelux region
    EFI appoints Frank Pennisi CEO, Fiery now an independent business
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Essity’s Sales Grow
    Thinx to Pay up to $5 million to Settle Class Action Suit
    Typar Highlighting New Building Innovations
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    Roche, Sysnav Partner on Movement Tracking Tech for Neuromuscular Disorders
    Orthopedic Braces/Support, Casting/Splints Market to Top $12B by 2030
    Orthofix Launches the Mariner Deformity System
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Celanese Launches Nine New Conductive Inks
    NREL Develops Thin, Lightweight Layer for Radiation Barrier for Perovskites in Space
    LG Display Reports Fourth Quarter 2022 Results

    Copyright © 2023 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login