Mike Montemarano, Associate Editor 05.25.21
Ingredients supplier Lycored recently announced the results of a preclinical, in vitro study which evidenced that Lumenato, a blend of tomato nutrients and antioxidants, could improve collagen levels in the skin, with researchers concluding that this could potentially protect the skin from damage related to age and UV damage.
The study, published in PLoS One, specifically highlighted that the extract was able to prevent the loss of type III collagen, a collagen type which decreases in response to inflammatory cytokines, which are known to be induced by UV and other threats to skin health.
Lumenato was shown to potentially defend against collagen-3 damage due to a mechanism that involves balancing oxidative stress and reducing the free radicals secreted by neutrophils. These immune cells are found within the skin and have been shown in prior research to play a major role in collagen damage.
“Although Lumenato inhibited MMP-8, MMP-9, and elastase secreted from neutrophils, its main effect was in inhibiting both NADPH oxidase-producing superoxides and the MPO activity-producing halides in a dose-dependent manner that correlated with protection from collagen-3 damage,” the authors of the study concluded. “The results suggest that Lumenato induces low levels of collagen-3 that may contribute for skin health and is very effective in defending the co-cultures from collagen-3 damage by inhibiting free radicals secreted from neutrophils, thus, indicating Lumenato’s possible potential for skin protection.
“Our skin is impacted by both internal and environmental challenges that may accelerate skin aging,” Karin Hermoni, head of product and science at Lycored, said. “This can initiate a cascade of events that includes local damage such as inflammatory and oxidative damage and leads to collagen degradation and visible aging of the skin. This research shows that Lumenato could play an important role in balancing the skin’s response. With high concentrations of phytofluene and phytoene, Lumenato harnesses the natural power fo the tomato to support skin from the inside out and helps us age beautifully.”
Lumenato is designed to make phytonutrients available to the skin to boost the health and appearance of skin – as an ingestible skincare supplement ingredient, Lumenato is plant-based, vegetarian, allergen-free, gluten-free, Kosher, Halal, and Non-GMO Project verified.
Mike Montemarano has been the Associate Editor of Nutraceuticals World since February 2020. He can be reached at mmontemarano@rodmanmedia.com.
The study, published in PLoS One, specifically highlighted that the extract was able to prevent the loss of type III collagen, a collagen type which decreases in response to inflammatory cytokines, which are known to be induced by UV and other threats to skin health.
Lumenato was shown to potentially defend against collagen-3 damage due to a mechanism that involves balancing oxidative stress and reducing the free radicals secreted by neutrophils. These immune cells are found within the skin and have been shown in prior research to play a major role in collagen damage.
“Although Lumenato inhibited MMP-8, MMP-9, and elastase secreted from neutrophils, its main effect was in inhibiting both NADPH oxidase-producing superoxides and the MPO activity-producing halides in a dose-dependent manner that correlated with protection from collagen-3 damage,” the authors of the study concluded. “The results suggest that Lumenato induces low levels of collagen-3 that may contribute for skin health and is very effective in defending the co-cultures from collagen-3 damage by inhibiting free radicals secreted from neutrophils, thus, indicating Lumenato’s possible potential for skin protection.
“Our skin is impacted by both internal and environmental challenges that may accelerate skin aging,” Karin Hermoni, head of product and science at Lycored, said. “This can initiate a cascade of events that includes local damage such as inflammatory and oxidative damage and leads to collagen degradation and visible aging of the skin. This research shows that Lumenato could play an important role in balancing the skin’s response. With high concentrations of phytofluene and phytoene, Lumenato harnesses the natural power fo the tomato to support skin from the inside out and helps us age beautifully.”
Lumenato is designed to make phytonutrients available to the skin to boost the health and appearance of skin – as an ingestible skincare supplement ingredient, Lumenato is plant-based, vegetarian, allergen-free, gluten-free, Kosher, Halal, and Non-GMO Project verified.
Mike Montemarano has been the Associate Editor of Nutraceuticals World since February 2020. He can be reached at mmontemarano@rodmanmedia.com.
