01.18.21
Several observational studies have established mixed evidence that maternal intake of both fish and omega-3 fatty acids (EPA and DHA) during gestation is beneficial to a child’s psychomotor development in the years to come. A recent large-scale review, published in the Journal of Clinical Nutrition, furthered this claim after reporting significant differences between children whose mothers consumed high amounts of fish and omega-3s, versus those who were on the lower end of the spectrum.
The study specifically looked at maternal intake of fish and omega-3s, and observed childhood neurodevelopment at the age of 6 months and 1 year. 81,697 mother-child pairs at the age of 6 months were evaluated, in addition to 77,751 mother-child pairs at the age of 1 year.
Maternal fish intake during pregnancy was independently associated with a reduced risk of delay in problem-solving skills at the age of 6 months, as well as in fine motor skills and problem solving by the time the child reached one year of age. Looking at omega-3 fatty acids specifically, the authors concluded that an increased maternal intake was associated with a reduced risk of delay in fine motor skills ant 6 months, and in fine motor skills and problem solving at one year of age.
Maternal intake of omega-6 fatty acids was associated with a reduced risk of delay in communication and fine motor skills at 6 months old, and in gross motor skills, fine motor skills, and problem solving at one year old. However, it was shown that a high omega-6:omega-3 ratio was positively associated with an increased risk of delayed problem solving at one year old.
“Besides DHA, arachidonic acid (AA) is also an important PUFA,” the authors said. “It is abundant in the gray matter, and is a required precursor for eicosanoids such as PGs, thromboxane, and leukotriene, which are potent regulator and inflammatory substances […] Our results showed that the effects of omega-6 PUFAs on neurodevelopment were similar to those of omega-3 PUFAS. However, for the omega-6/omega-3 ratio, detrimental effects emerged for the problem-solving domain in the highest quintile group.”
The reason for this is unclear, the authors said, but limited evidence suggests that AA has a role in heightening a risk of preterm birth, which is tied deeply to neurological development. Further, they conclude that further research is needed to see if beneficial effects present at such an early age persist into areas such as mental health and behavior later in life.
“In terms of clinical implications, the evidence supporting the efficacy of omega-3 PUFAs in child neurodevelopment is still inconsistent,” the authors concluded. “However, because there is considerable evidence of the beneficial effects of fish consumption on neurodevelopment, we advocate that fish – especially fatty fish – be recommended to pregnant women, as long as the fish species are limited to those not containing methylmercury […] more follow-up is needed to explore other aspects of neurodevelopment such as mental health and behavior.”
The study specifically looked at maternal intake of fish and omega-3s, and observed childhood neurodevelopment at the age of 6 months and 1 year. 81,697 mother-child pairs at the age of 6 months were evaluated, in addition to 77,751 mother-child pairs at the age of 1 year.
Maternal fish intake during pregnancy was independently associated with a reduced risk of delay in problem-solving skills at the age of 6 months, as well as in fine motor skills and problem solving by the time the child reached one year of age. Looking at omega-3 fatty acids specifically, the authors concluded that an increased maternal intake was associated with a reduced risk of delay in fine motor skills ant 6 months, and in fine motor skills and problem solving at one year of age.
Maternal intake of omega-6 fatty acids was associated with a reduced risk of delay in communication and fine motor skills at 6 months old, and in gross motor skills, fine motor skills, and problem solving at one year old. However, it was shown that a high omega-6:omega-3 ratio was positively associated with an increased risk of delayed problem solving at one year old.
“Besides DHA, arachidonic acid (AA) is also an important PUFA,” the authors said. “It is abundant in the gray matter, and is a required precursor for eicosanoids such as PGs, thromboxane, and leukotriene, which are potent regulator and inflammatory substances […] Our results showed that the effects of omega-6 PUFAs on neurodevelopment were similar to those of omega-3 PUFAS. However, for the omega-6/omega-3 ratio, detrimental effects emerged for the problem-solving domain in the highest quintile group.”
The reason for this is unclear, the authors said, but limited evidence suggests that AA has a role in heightening a risk of preterm birth, which is tied deeply to neurological development. Further, they conclude that further research is needed to see if beneficial effects present at such an early age persist into areas such as mental health and behavior later in life.
“In terms of clinical implications, the evidence supporting the efficacy of omega-3 PUFAs in child neurodevelopment is still inconsistent,” the authors concluded. “However, because there is considerable evidence of the beneficial effects of fish consumption on neurodevelopment, we advocate that fish – especially fatty fish – be recommended to pregnant women, as long as the fish species are limited to those not containing methylmercury […] more follow-up is needed to explore other aspects of neurodevelopment such as mental health and behavior.”
