• Login
    • Join
  • FOLLOW:
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Exclusives
    • Nutraceuticals
    • Markets
    • Health
    • Jobs
    • Events
    • Buyers' Guide
    • Showcases
    • More
  • Magazine
  • News
  • Exclusives
  • Nutraceuticals
  • Markets
  • Health
  • Jobs
  • Events
  • Buyers' Guide
  • Showcases
  • Current & Past Issues
    Features
    Columns
    Editorials
    Digital Edition
    Subscribe Now
    Advertise Now
    eNewsletter
    Editorial Guidelines
    Top Features
    Contract Manufacturing: Trials & Tribulations of Today’s Supply Chains

    Analytical Testing in Nutraceuticals: Methods and Mindsets to Uphold Quality

    Nutrition and Flavor: Formulating for Modern Product Preferences

    What Do Consumers Know About the Gut Microbiome?

    How Will the European Green Deal Impact Dietary Supplements?
    Breaking News
    Certifications, Approvals and Patents
    Exclusives
    Industry & Market News
    People
    Products
    Regulatory
    Research
    Supplier News
    Supplier Insights
    Live From Shows
    Top News
    Charlotte’s Web Sports Product Line to Undergo NSF Certification Process

    ADM and Benson Hill Partner to Scale High Protein Soy for U.S. Market

    Tazo Transitions to Regenerative Organic Agriculture

    Protein Ingredient Formulated for Chronic Kidney Disease Patients

    IADSA Calls for Addressing Discrepancies in Vitamin C Recommendations
    Exclusives
    Blogs & Guest Articles
    Health E-Insights
    Area Code 420
    eBook
    Antioxidants
    Dairy-Based Ingredients
    Enzymes
    Fatty Acids
    Fiber & Carbohydrates
    Green Foods
    Herbs & Botanicals
    Marine Nutraceuticals
    Minerals
    Omega 3s
    Probiotics & Prebiotics
    Proteins, Peptides, Amino Acids
    Sweeteners
    Vitamins

    Fact or Myth: Antioxidants Negatively Impact Iron Absorption

    Charlotte’s Web Sports Product Line to Undergo NSF Certification Process

    ADM and Benson Hill Partner to Scale High Protein Soy for U.S. Market

    Tazo Transitions to Regenerative Organic Agriculture

    Protein Ingredient Formulated for Chronic Kidney Disease Patients
    Consumer Trends
    Contract Manufacturing
    Cosmeceuticals / Nutricosmetics
    Delivery & Dosage Technologies
    Dietary Supplements
    Flavors & Colors
    Functional Foods & Beverages
    Healthcare Trends
    Medical Nutrition
    Mergers & Acquisitions
    Natural/Organic
    Nutrition Bars
    Packaging
    Pet Nutraceuticals
    Quality & Safety
    Regulations
    Research
    Testing
    World Markets

    Fact or Myth: Antioxidants Negatively Impact Iron Absorption

    Charlotte’s Web Sports Product Line to Undergo NSF Certification Process

    ADM and Benson Hill Partner to Scale High Protein Soy for U.S. Market

    Tazo Transitions to Regenerative Organic Agriculture

    Protein Ingredient Formulated for Chronic Kidney Disease Patients
    Bone & Joint Health
    Cancer Risk
    Cardiovascular Health
    Cognitive Function
    Diabetes & Blood Sugar Management
    Digestive Health
    Energy
    Eye Health
    Healthy Aging
    Immune Function
    Infant & Children's Health
    Inflammation
    Men's Health
    Mood Health & Sleep
    Oral Health
    Sexual & Reproductive Health
    Skin Health
    Sports Nutrition
    Weight Management/Weight Loss
    Women's Health

    Charlotte’s Web Sports Product Line to Undergo NSF Certification Process

    Caffeine-Free Energy Supplement Linked to Alertness, Fatigue Benefits

    Monk Fruit Sweetener May Have Prebiotic Activity, Study Finds

    People with Low-Fiber Diets Benefit the Most from Fiber Supplements, Study Finds

    Gut Microbiome May Be Part of Link Between Red Meat and Heart Disease Risk
    Industry Events
    Live From Show Events
    Webinars
    All Companies
    Categories
    Trade Associations
    Company Capabilities
    International Buyers Guide Companies
    Ecuadorian Rainforest

    Botanic Healthcare LLC

    JRS Pharma

    ESHA Research

    Bioenergy Life Science, Inc. (BLS)
    Companies
    Product Releases
    News Releases
    Literature / Brochures
    White Papers
    Jobs
    VIdeos
    Services
    Add New Company
    International Buyers Guide Companies
    Ecuadorian Rainforest

    Botanic Healthcare LLC

    JRS Pharma

    ESHA Research

    Bioenergy Life Science, Inc. (BLS)
    • Magazine
      • Current / Back Issue
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Editorial Guidelines
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Buyers' Guide
      • All Companies
      • Categories
      • Trade Associations
      • Company Capabilities
    • Nutraceuticals
      • Antioxidants
      • Dairy-Based Ingredients
      • Enzymes
      • Fatty Acids
      • Fiber & Carbohydrates
      • Green Foods
      • Herbs & Botanicals
      • Marine Nutraceuticals
      • Minerals
      • Omega 3s
      • Probiotics & Prebiotics
      • Proteins, Peptides, Amino Acids
      • Sweeteners
      • Vitamins
    • Markets
      • Consumer Trends
      • Contract Manufacturing
      • Cosmeceuticals / Nutricosmetics
      • Delivery & Dosage Technologies
      • Dietary Supplements
      • Flavors & Colors
      • Functional Foods & Beverages
      • Healthcare Trends
      • Medical Nutrition
      • Mergers & Acquisitions
      • Natural/Organic
      • Nutrition Bars
      • Packaging
      • Pet Nutraceuticals
      • Quality & Safety
      • Regulations
      • Research
      • Testing
      • World Markets
    • Health
      • Bone & Joint Health
      • Cancer Risk
      • Cardiovascular Health
      • Cognitive Function
      • Diabetes & Blood Sugar Management
      • Digestive Health
      • Energy
      • Eye Health
      • Healthy Aging
      • Immune Function
      • Infant & Children's Health
      • Inflammation
      • Men's Health
      • Mood Health & Sleep
      • Oral Health
      • Sexual & Reproductive Health
      • Skin Health
      • Sports Nutrition
      • Weight Management/Weight Loss
      • Women's Health
    • Online Exclusives
    • Webinars
    • Slideshows
    • Blogs & Guest Articles
    • Health E-Insights
    • Videos
    • Podcasts
    • Infographics
    • eBook
    • Whitepapers
    • Research
      • TrendSense
      • Monograph Center
      • White Papers
      • Research News
    • Jobs
    • Events
      • Industry Events
      • Live From Show Events
      • Webinars
    • Supplier Showcases
      • Companies
      • Product Releases
      • News Releases
      • Literature / Brochures
      • White Papers
      • Jobs
      • VIdeos
      • Services
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Breaking News

    Vitamin K2 RDI Program Spearheaded by NattoPharma

    K2 leader joins with researchers to establish basis for an RDI.

    Related CONTENT
    • Balchem Agrees to Acquire Kappa Bioscience AS
    • Vitamin K Status Associated with Cognitive Test Performance in Elderly Adults
    • Gnosis by Lesaffre: The Preeminent Vitamin K2 Supplier
    • Frezzor New Zealand Launches Vitamin D3 Sourced from Sheep’s Wool
    • Blue California: Delivering Sustainable, Evidence-Based Solutions for a Healthy Mind and Body
    05.31.18
    Global cardiovascular and bone health has been negatively impacted by widespread vitamin K2 deficiency. Yet there is no established RDI (Recommended Daily Intake) for vitamin K2. To that end, as a leader in vitamin K2, NattoPharma has enlisted its research partners to start a program to establish a much-needed RDI for vitamin K2. 
     
    The program will begin with a team of researchers at Maastricht University, the Netherlands, the group that has led the way discovering and validating the health benefits of vitamin K2, guided by Dr. Leon Schurgers, professor of biochemistry of vascular calcification at Cardiovascular Research Institute at Maastricht University(CARIM). NattoPharma has worked closely with the Maastricht University in documenting benefits of the company’s exclusive branded MenaQ7 vitamin K2 as MK-7, since 2004—work that has been recognized with many peer-reviewed scientific papers and with recently awarded research grants. 
     
    “The RDI for vitamin K is established based on coagulation factors only, but research continues to emerge that vitamin K and vitamin K-dependent proteins have physiological roles beyond coagulation,” said Dr. Schurgers, noting that the AI (Adequate Intake) for vitamin K was established at 90 μg/d for women and 120 μg/d for men for the U.S. and Canada, and in Europe it is 1 μg/Kg/d. This was based on median phylloquinone (vitamin K1) intakes estimated from national surveys back in 2001. Next to vitamin K1 our food also provides us with vitamin K2. “More recent research has confirmed different bioavailability / activity between K1 and K2, and additional biological functions of K2 due to different side chains. Further, all epidemiological and interventional studies showed that only K2 was cardio-protective or has a beneficial effect on the arteries. This has not been considered in the forming of dietary recommendations.”
     
    Dr. Schurgers’ team will be joined by the International Science and Health Foundation (ISHF), a research consortium responsible for the educational portal VitaminK2.org.  According to Dr. Katarzyna Maresz, ISHF president, VitaminK2.org was specifically created to educate consumers and practitioners about the proven benefits of vitamin K2, recognizing the impact of widespread K2 deficiency. 
     
    “We have seen in comprehensive studies—in adults as well as children – that correcting Vitamin K2 deficiency can greatly improve bone health, and studies in adults have delivered unprecedented improvement in cardiovascular health,” she saod. “Yet studies also show that 97% of the Western population remains deficient. Establishing an RDI is an important step in educating the public about their absolute dietary need, providing them much-needed direction.”  
     
    According to Dr. Maresz, one of the first hurdles to overcome establishing an RDI is to have a biomarker or clinical endpoint that reflects the consequences of inadequate K2 consumption. 
     
    “Scientific knowledge has changed a lot recently, yet there is still a lack of suitable biomarkers or clinical endpoints that can be used to determine vitamin K2 requirements among adults,” she explained, offering that inactive Matrix Gla Protein (dpucMGP) or the ratio of inactive to inactive Osteocalcin (ucOC/cOC) could be used as markers of vitamin K status. “Given that some vitamin K deficiency or insufficiency has been seen in 97% of older subjects in a mixed population as reflected by their measures of dpucMGP, this could be a good starting marker. However, the ‘normal’ range should be established. Further, K1 influences these markers, too, and we have to consider the metabolic events such the inter-conversion of phylloquinone to MK-4.” 
     
    Both NattoPharma and the researchers recognize the scope of this undertaking, but also that it is time to begin. 
     
    “Convincing the government to recognize how essential specific nutrients are is an arduous process,” said Eric Anderson, senior vice president of global marketing and business development with NattoPharma. “We have been working with Maastricht University for almost two decades validating the health benefits of vitamin K2, creating this category. Our work, in addition to others’, is building that body of evidence. Now it is time to lead the way ensuring that a global recommendation exists so we can ensure vitamin K2 is adequately attained for the betterment of the world population—men and women, adults and children.”
     
    To that end, through the Horizon 2020 grants awarded in which the CARIM is the beneficiary, in partnership with NattoPharma, the company will host PhD students (ESRs) to teach them about the food and supplement industry and foster a further understanding of the RDI values set by FDA/EFSA. These ESRs will utilize this knowledge as they conduct a comprehensive literature review elucidating the data for K2’s bone and cardiovascular benefits. This cogent argument will work towards the efforts of petitioning for RDIs. 
    Related Searches
    • nattopharma
    • Research
    • Nutrients
    • fda
    Related Knowledge Center
    • Bone & Joint Health
    • Vitamins
    • Cardiovascular Health
    Suggested For You
    Balchem Agrees to Acquire Kappa Bioscience AS Balchem Agrees to Acquire Kappa Bioscience AS
    Vitamin K Status Associated with Cognitive Test Performance in Elderly Adults Vitamin K Status Associated with Cognitive Test Performance in Elderly Adults
    Gnosis by Lesaffre: The Preeminent Vitamin K2 Supplier Gnosis by Lesaffre: The Preeminent Vitamin K2 Supplier
    Frezzor New Zealand Launches Vitamin D3 Sourced from Sheep’s Wool Frezzor New Zealand Launches Vitamin D3 Sourced from Sheep’s Wool
    Blue California: Delivering Sustainable, Evidence-Based Solutions for a Healthy Mind and Body Blue California: Delivering Sustainable, Evidence-Based Solutions for a Healthy Mind and Body
    Vitamin K2 Reduces Oxidative Stress, Increases ATP Production, Study Finds Vitamin K2 Reduces Oxidative Stress, Increases ATP Production, Study Finds
    Why Vegans Should Consider Supplementing with Vitamin K2 (MK-7) Why Vegans Should Consider Supplementing with Vitamin K2 (MK-7)
    Active Nutrition Market Expands to Meet Modern Health Challenges Active Nutrition Market Expands to Meet Modern Health Challenges
    Kappa BioScience Forms Scientific and Medical Advisory Board Kappa BioScience Forms Scientific and Medical Advisory Board
    ICYMI: What People Were Reading on NutraceuticalsWorld.com in January 2022 ICYMI: What People Were Reading on NutraceuticalsWorld.com in January 2022
    Vitamin and Mineral Supplements Offer A Sturdy Industry Foundation Vitamin and Mineral Supplements Offer A Sturdy Industry Foundation
    Vitamin K Status May Have Stronger Impact on COVID-19 Than Vitamin D Deficiency Vitamin K Status May Have Stronger Impact on COVID-19 Than Vitamin D Deficiency
    Gnosis by Lesaffre Launches Vitamin K2 Protective Matrix Gnosis by Lesaffre Launches Vitamin K2 Protective Matrix
    An Interview with Hikaru Asari, Senior Executive, J-Oil Mills, Inc. An Interview with Hikaru Asari, Senior Executive, J-Oil Mills, Inc.
    Heart Health Dietary Supplement Market Influences & Opportunities Heart Health Dietary Supplement Market Influences & Opportunities

    Related Breaking News

    • Breaking News | Mergers & Acquisitions | Supplier News | Vitamins | World Markets
      Balchem Agrees to Acquire Kappa Bioscience AS

      Balchem Agrees to Acquire Kappa Bioscience AS

      The vitamin K2 supplier was purchased from majority owner Verdane Edda for approximately $338 million.
      06.14.22

    • Breaking News | Cognitive Function | Medical Nutrition | Research News | Vitamins
      Vitamin K Status Associated with Cognitive Test Performance in Elderly Adults

      Vitamin K Status Associated with Cognitive Test Performance in Elderly Adults

      A study on 800 older adults found a link between cognitive function and osteocalcin, a biomarker for low vitamin K status.
      04.26.22

    • Delivery & Dosage Technologies | Dietary Supplements | Video Bites | Vitamins
      Gnosis by Lesaffre: The Preeminent Vitamin K2 Supplier

      Gnosis by Lesaffre: The Preeminent Vitamin K2 Supplier

      Global Market Manager Xavier Berger discusses the company’s new technology that will allow for the creation of more complex K2 formulations.


    • Breaking News | Delivery & Dosage Technologies | Natural/Organic | Supplier News | Vitamins
      Frezzor New Zealand Launches Vitamin D3 Sourced from Sheep’s Wool

      Frezzor New Zealand Launches Vitamin D3 Sourced from Sheep’s Wool

      The company exclusively uses wool from 100% grass-fed, free-range sheep for traceability.
      04.08.22

    • Antioxidants | Dietary Supplements | Healthy Aging | Supplier Insights
      Blue California: Delivering Sustainable, Evidence-Based Solutions for a Healthy Mind and Body

      Blue California: Delivering Sustainable, Evidence-Based Solutions for a Healthy Mind and Body

      Company’s expanded portfolio includes ingredients produced via fermentation and enzymatic conversion to target key areas of health.

    Loading, Please Wait..
    Trending
    • Study Examines Vitamin K2 Content In Cheese
    • Chenland Nutritionals Self-Affirms GRAS For Cumin UP60 Ingredient
    • Pycnogenol Evidenced To Have Skin Benefits In Dermatology Study
    • ADM And Benson Hill Partner To Scale High Protein Soy For U.S. Market
    Breaking News
    • Charlotte’s Web Sports Product Line to Undergo NSF Certification Process
    • ADM and Benson Hill Partner to Scale High Protein Soy for U.S. Market
    • Tazo Transitions to Regenerative Organic Agriculture
    • Protein Ingredient Formulated for Chronic Kidney Disease Patients
    • IADSA Calls for Addressing Discrepancies in Vitamin C Recommendations
    View Breaking News >
    CURRENT ISSUE

    July/August 2022

    • A Growing Herbal Products Market Still Faces Formidable Threats, Challenges
    • Analytical Testing in Nutraceuticals: Methods and Mindsets to Uphold Quality
    • Nutrition and Flavor: Formulating for Modern Product Preferences
    • Contract Manufacturing: Trials & Tribulations of Today’s Supply Chains
    • How Will the European Green Deal Impact Dietary Supplements?
    • What Do Consumers Know About the Gut Microbiome?
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    Charlotte’s Web Sports Product Line to Undergo NSF Certification Process
    ADM and Benson Hill Partner to Scale High Protein Soy for U.S. Market
    Tazo Transitions to Regenerative Organic Agriculture
    Coatings World

    Latest Breaking News From Coatings World

    What are you Reading this Week?
    SONGWON Industrial Group Reports Strong Q2 Financial Results
    PPG Completes COLORFUL COMMUNITIES Project for Boys & Girls Clubs of Greater Houston
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    MPO's Most-Read Stories This Week—Aug. 13
    'Graft-on-a-Chip' Built to Improve Vascular Graft Success
    Abbott Invests €440 in New Irish Facility
    Contract Pharma

    Latest Breaking News From Contract Pharma

    AskBio Appoints Clinical Ops Executives
    SpectrumX Partners With UK Contract Manufacturer
    GL Chemtec Partners with Edgewater Capital to Accelerate Growth
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Arkay Chairman Emeritus Howard Kaneff Has Died
    Nutricosmetics Market to Hit $13.7 Billion by 2030
    Estée Lauder Pledges 100% Electric Fleet of Vehicles by 2030
    Happi

    Latest Breaking News From Happi

    Kayali’s Lovefest Fragrance, Newell’s New Candle and HydraFacial’s Record Financial Results
    Self Care Trumps Home Care Post-Covid
    Sephora’s Virtual House of Beauty Returns with Exclusive Offerings
    Ink World

    Latest Breaking News From Ink World

    Weekly Recap: Printing Ink Primer, Zeller+Gmelin Lead This Week’s News Stories
    Heidelberg Enjoys Successful Start to 2022-23 Fiscal Year
    Mimaki Announces New LATAM Website
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Esko, Constantia Flexibles announce acquisitions and more
    Hybrid Software joins The Flexo Xperience Center
    Flexo Wash LLC and Mike Potter celebrate 20 years
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Focke & Co. to Host Destination: Your Hygiene Hub on August 31
    Exports Dominate Chinese Trade of Tissues, Hygiene Products and Wipes
    Freudenberg to Present Friction Inserts for Wind Energy
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    ODT's Most-Read Stories This Week—Aug. 13
    Dental 3D Printing Market is Expanding 20% Annually
    Study Results Released for Abbott's Concussion Blood Test
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Weekly Recap: ALTANA, Universal Display and Emerson Top This Week’s Stories
    eMagin Corporation Announces 2Q 2022 Results
    Zebra Technologies’ Emission Reduction Targets Validated by SBTi

    Copyright © 2022 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login