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The electrolyte mix is the first sugar-free option to be evaluated in a clinical study, the company reported.
May 28, 2026
By: Mike Montemarano
Associate Editor, Nutraceuticals World
Trace Minerals’ Zerolyte was shown to hydrate people twice as quickly as water following exercise-induced dehydration, according to a clinical trial conducted by the Hydration Science Lab at Arizona State University. The findings of the study will be presented at the American College of Sports Medicine (ACSM).
The study was led by Stavros Kavouras, PhD, a professor and director of the Hydration Science Lab. The randomized, crossover study enrolled men and women who underwent an exercise dehydration protocol before rehydrating with ZeroLyte or plain water. Researchers measured body weight restoration, urine output, skin hydration, blood markers, and perceptual responses at multiple intervals over four hours.
ZeroLyte outperformed water at every post-rehydration time point, with treated participants producing roughly half the urine volume compared to the plain water condition, indicating improved fluid retention.
“In this study, we observed that electrolyte composition plays a critical role in post-exercise rehydration,” said Kavouras. “The ZeroLyte formulation demonstrated improved fluid retention compared to water alone, which is an important factor in effective hydration.”
Notably, ZeroLyte contains no sugar of any kind. Some products marketed as sugar-free actually contain allulose, the company noted.
“This research confirms that the right electrolyte blend is the key to superior hydration,” said Darrin Starkey, ND, manager of education and training at Trace Minerals. “ZeroLyte was designed to replenish what the body loses during exercise, and now we have evidence that the first clinically studied, truly sugar-free electrolyte drink can restore body fluids two times faster than water.”
ZeroLyte contains ancient sea salt, coconut water, potassium, magnesium, and Trace Minerals’ signature full-spectrum ionic trace mineral complex sourced from Utah’s Great Salt Lake. It is formulated to support hydration and body fluid regulation, nerve and muscle function, and replenishment of electrolytes lost through exercise and daily activity.
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