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The review addresses clinical studies on the botanical formulas’ effects on gut motility, microbioal balance, inflammation, and overall digestive well-being.
September 18, 2024
By: Mike Montemarano
Associate Editor, Nutraceuticals World
A new review published in Cureus highlights evidence supporting the role of Freemen Nutra and NXT USA’s Digexin, a blend of ashwagandha and okra extracts, in supporting digestive health. The review covers studies on the ingredient’s safety profile and efficacy in supporting overall digestive wellness, gut motility, microbial balance, and inflammation reduction. Digexin is unique in that it addresses gut health while also increasing serotonin and decreasing cortisol levels, suggesting that the ingredient works upon the gut-brain axis (GBA) to alleviate gastrointestinal disorders that are impacted by mood and stress. “Until now, gut health products really have only referred to the gut-brain axis in terms of modulating the gut for some downstream benefit of the mind or various other systems,” said Eric Withee, director of ingredient innovation at Freemen Nutra. “Products that work through the mind to alleviate GI issues like constipation, indigestion, or reflux are effectively non-existent. Half of all GI disorders originate in the mind, and the mind arguably exerts the most influence over symptom presentation and intensity. Until Digexin, the number of brain-to-gut solutions has been zero.” Digexin has been featured in a variety of gastrointestinal health supplements, functional foods, and beverages. “We believe Digexin will be a transformative addition to the market, offering manufacturers an innovative ingredient backed by robust research,” said Eric Anderson, general manager of NXT USA. “Our commitment to advancing natural health solutions is reflected in the rigorous research and development that went into Digexin.”
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