Everwell Health, the parent company of ingredient supplier Nutrition21, has announced that it has acquired American River Nutrition (ARN) from Designs for Health. The ingredient supplier specializes in extracts of annatto. The acquisition includes ARN’s patented, branded ingredients DeltaGold and GG-Gold, along with other functional ingredients and international property.

The brand will continue its operations in Hadley, Massachusetts at its manufacturing site, which will also continue to serve as its primary innovation center. The ingredient DuoQuinol is not part of the transaction, and Designs for Health will continue to own it.

ARN was founded in 1998 by Barrie Tan, PhD, with a focus on scientific advancement on the health benefits of Bixa Orellana, a tropical plant commonly known as annatto. Its ingredient portfolio includes DeltaGold, a tocopherol-free source of tocotrienols offering a range of antioxidant benefits, and GG-Gold Geranylgeraniol, an endogenous nutrient that declines with age and is associated with protein synthesis and production of testosterone, progesterone, CoQ10, and MK4.

ARN uses proprietary processes and technologies to produce its ingredients, which involve a specialized distillation process to isolate and concentrate bioactive compounds without the use of solvents or harsh chemicals. The facility has an in-house lab for analytical analysis, quality control, and research and development.

“Our acquisition of American River Nutrition reinforces our commitment to providing scientifically substantiated ingredients which support consumers in living life to their fullest potential,” said Steve Rosenman, CEO of Everwell Health. “These unique and powerful plant-based ingredients further build upon our vision to deliver ingredients that empower all to look, feel, and perform their best. Our customers will benefit from new opportunities that our expanded ingredient portfolio delivers to innovate new products in key health areas including metabolic, cardiovascular, mitochondrial, men’s health, muscle, and bone health. Beyond the ingredient portfolio, the vertical integration of ARN’s highly specialized manufacturing facility adds value and strengthens our capabilities as we will continue investing in nature-based bioactive ingredients.”

“Everwell Health shares our commitment to science, quality, and innovation, and we know ARN will thrive under Everwell’s leadership,” said Amardeep Kahlon, CEO of Designs for Health. “This move positions Designs for Health to further deliver on our core mission of advancing clinical nutrition and integrative health solutions through healthcare practitioners with our core Designs for Health products.”

All of ARN’s commercial and manufacturing operations will continue without interruption, and the brand will operate as American River Nutrition, an Everwell Health Company for the remainder of 2025, before integrating into Everwell’s portfolio of brands. During this process, ARN’s customers and supply chain partners will gain access to the capabilities and expertise of Everwell Health.