06.20.11
A new study, conducted at the University of Indonesia, shows the olive leaf extract Benolea from Frutarom is as efficient as the widely used pharmaceutical Captopril in lowering elevated blood pressure levels. The company presented results during this year’s Vitafoods in Geneva, Switzerland. According to the study, Benolea significantly reduces total cholesterol and plasma triglyceride levels, an effect which was not observed with the conventional drug.
The randomized, double-blind, double-dummy, active controlled study involved 232 participants aged 25 to 60 years with stage-1 hypertension (systolic blood pressure 140-159 mmHg, and/or diastolic blood pressure 90-99 mmHg) who were not taking any medication or were asked to stop it upon consent. A four-week run-in period without treatment was followed by eight weeks of treatment with either one 500 mg Benolea caplet or one 12.5 mg Captopril tablet, each taken twice a day. After two weeks, if participants showed no response to Captopril, they received a double dose of the drug.
At the end of the study, both Benolea and Captopril had clearly lowered systolic and diastolic blood pressure compared to baseline. The reduction of blood pressure in the natural treatment group with Benolea was comparable to the pharmaceutical group with Captopril.
With regards to lipid profile, Benolea significantly reduced total cholesterol and triglyceride levels, particularly in participants with high baseline triglyceride levels (>200 mg/dl). Triglycerides diminished by 53.13 mg/dl. Such positive effects were not observed in the Captopril group. For further information: www.frutarom.com
The randomized, double-blind, double-dummy, active controlled study involved 232 participants aged 25 to 60 years with stage-1 hypertension (systolic blood pressure 140-159 mmHg, and/or diastolic blood pressure 90-99 mmHg) who were not taking any medication or were asked to stop it upon consent. A four-week run-in period without treatment was followed by eight weeks of treatment with either one 500 mg Benolea caplet or one 12.5 mg Captopril tablet, each taken twice a day. After two weeks, if participants showed no response to Captopril, they received a double dose of the drug.
At the end of the study, both Benolea and Captopril had clearly lowered systolic and diastolic blood pressure compared to baseline. The reduction of blood pressure in the natural treatment group with Benolea was comparable to the pharmaceutical group with Captopril.
With regards to lipid profile, Benolea significantly reduced total cholesterol and triglyceride levels, particularly in participants with high baseline triglyceride levels (>200 mg/dl). Triglycerides diminished by 53.13 mg/dl. Such positive effects were not observed in the Captopril group. For further information: www.frutarom.com