The European Foods Safety Authority (EFSA) has issued a scientific opinion on health claims in relation to dietary consumption of hydroxytyrosol and related polyphenol compounds from olive fruit and oil and protection of blood lipids from oxidative damage, which is known to affect cardiovascular health adversely. On the basis of the data presented, EFSA concluded that a cause-and-effect relationship has been established between the consumption of hydroxytyrosol and related compounds from olives and olive oil and protection of blood lipids from oxidative damage. EFSA determined that a minimum 5 mg of Hydroxytyrosol and its derivatives in olive oil should be consumed daily to use a cardiovascular health claim. Hydroxytyrosol is the active ingredient in Hytolive, a proprietary extract of olive fruit manufactured by Genosa ID, S.A., Malaga, Spain and distributed by PL Thomas, Morristown, NJ. Hytolive has a high concentration of natural hydroxytyrosol, the active and most abundant ortho-diphenol found in the olive fruit.