05.01.07
Indication: Gastric cancer
Source: Am J Clin Nutr, February 2007;85(2):497-503.
Research: Vitamin A may influence gastric carcinogenesis through its essential role in controlling cell proliferation and differentiation. However, epidemiologic studies of vitamin A, retinol (preformed vitamin A), and provitamin A carotenoids in relation to the risk of gastric cancer have documented inconsistent results. So researchers set out to examine the associations between intakes of vitamin A, retinol, and specific carotenoids and the risk of gastric cancer in a prospective population-based cohort study of Swedish adults. The study cohort consisted of over 82,000 Swedish adults aged 45–83, who had completed a food-frequency questionnaire in 1997. The participants were followed through June 2005.
Results: During approximately 7 years of follow-up, 139 incident cases of gastric cancer were diagnosed. High intakes of vitamin A and retinol from foods only (dietary intake) and from foods and supplements combined (total intake) and of dietary alpha-carotene and beta-carotene were associated with a lower risk of gastric cancer. Researchers, however, found no significant associations for beta-cryptoxanthin, lutein and zeaxanthin, or lycopene intake.
Source: Am J Clin Nutr, February 2007;85(2):497-503.
Research: Vitamin A may influence gastric carcinogenesis through its essential role in controlling cell proliferation and differentiation. However, epidemiologic studies of vitamin A, retinol (preformed vitamin A), and provitamin A carotenoids in relation to the risk of gastric cancer have documented inconsistent results. So researchers set out to examine the associations between intakes of vitamin A, retinol, and specific carotenoids and the risk of gastric cancer in a prospective population-based cohort study of Swedish adults. The study cohort consisted of over 82,000 Swedish adults aged 45–83, who had completed a food-frequency questionnaire in 1997. The participants were followed through June 2005.
Results: During approximately 7 years of follow-up, 139 incident cases of gastric cancer were diagnosed. High intakes of vitamin A and retinol from foods only (dietary intake) and from foods and supplements combined (total intake) and of dietary alpha-carotene and beta-carotene were associated with a lower risk of gastric cancer. Researchers, however, found no significant associations for beta-cryptoxanthin, lutein and zeaxanthin, or lycopene intake.