By Julius Few, MD; Michael Lee, MD; Alec Semersky; Emily Mariscal, LE; and Ginny Vachon, PhD04.07.22
This article originally appeared in the Aesthetic Surgery Journal.
Retinol is known to reduce the appearance of fine lines and wrinkles, but is associated with irritating effects. Cannabidiol (CBD) acts to reduce oxidative stress and inflammation, mitigating irritation from retinol, and further improving the skin’s appearance through independent anti-aging mechanisms.
Skin aging is influenced by a number of factors, including extrinsic factors like exposure to UV light, poor diet, or pollutants, and intrinsic factors such as collagen and elastin loss over time.1 Within the skin, intrinsic aging is due, in part, to the decreased capacity of keratinocytes, fibroblasts, and melanocytes to proliferate, and the degeneration of the fibrous extracellular matrix, while 80% of extrinsic aging can be attributed to UV radiation.2-4 Interestingly, for both intrinsic and extrinsic aging, reactive oxygen species (ROS) and associated oxidative stress can accelerate these processes in the skin through multiple mechanisms and contribute to dyspigmentation, reduced barrier function, laxity, and uneven texture.1-5 In additi
Retinol is known to reduce the appearance of fine lines and wrinkles, but is associated with irritating effects. Cannabidiol (CBD) acts to reduce oxidative stress and inflammation, mitigating irritation from retinol, and further improving the skin’s appearance through independent anti-aging mechanisms.
Skin aging is influenced by a number of factors, including extrinsic factors like exposure to UV light, poor diet, or pollutants, and intrinsic factors such as collagen and elastin loss over time.1 Within the skin, intrinsic aging is due, in part, to the decreased capacity of keratinocytes, fibroblasts, and melanocytes to proliferate, and the degeneration of the fibrous extracellular matrix, while 80% of extrinsic aging can be attributed to UV radiation.2-4 Interestingly, for both intrinsic and extrinsic aging, reactive oxygen species (ROS) and associated oxidative stress can accelerate these processes in the skin through multiple mechanisms and contribute to dyspigmentation, reduced barrier function, laxity, and uneven texture.1-5 In additi
Continue reading this story and get 24/7 access to Nutraceuticals World for FREE
FREE SUBSCRIPTION
